Objective To investigate the clinical effects of two different partial splenic embolization (PSE) methods in treating portal hypertension due to cirrhosis, and to statistically analyze the difference between the two PSE methods. Methods Sixty-two patients with cirrhotic portal hypertension complicated by hypersplenism were divided into group A (peripheral embolization group) and Group B (lower- pole embolization group). Partial splenic embolization with sponge was carried out in all patients of both groups. Before and after PSE color Doppler ultrasoundgraphy was performed to determine the inner diameter of the portal vein and splenic vein, the velocity and rate of flow, the length and thickness of spleen, etc. The results were compared between the two groups. Results The splenic embolization area within 60% - 80%was obtained in 42 patients, and the embolization area>80%was seen in 20 patients. After PSE, decreased flow velocity as well as flow rate was detected in all patients, and both the length and thickness of the spleen were also significantly reduced when compared with the data determined before PSE. The differences between the two groups were statistically significantly (P < 0.05). Conclusion Partial splenic embolization can effectively relieve the portal hypertension caused by cirrhosis, and selective peripheral arterial embolization is superior to splenic lower-pole embolization in decreasing the portal pressure.

Objective:To analyze the clinical characteristics and treatment effect between bilateral(bi-)and unilateral(uni-) sudden sensorineural hearing loss(SSNHL).Method:Four hundred and eighty cases of SSNHL were retrospective study,which were divided into two groups of bi-SSNHL(n=40) and uni-SSNHL(n=440).Clinical characteristics and treatment effects were compared of the two groups.Result:The incidence rate of bi-SSNHL was 8.3 percent and uni-SSNHL was 91.7 percent of all patients with SSNHL. Bi-SSNHL occurs more commonly in patients of old age, diabetes mellitus, and lipid panes abnormalities compared to uni-SSNHL. Twenty-eight ears in the bi-SSNHL group showed hearing recovery (35%),compared with 56.4 percent of patients with uni-SSNHL.Conclusion:Bi-SSNHL and uni-SSNHL may have a completely different clinical characteristics and treatment effect,that implies a different pathophysiology and prognosis. Recognition their different clinical characteristics and treatment effect between bilateral and unilateral SSNHL can help in counseling and managing the patients and correctly evaluate the prognosis.

Objective To explore effect of family-centered discharge guidance on family care of premature infants in NICU.Methods A total of 174 premature infants with extremely low birth weight in NICU were studied and were randomly divided into study group and control group,with 87 cases per group.Control group received conventional discharge guidance while the study group received family-centered discharge planning.Height and weight changes of neonates at discharge,and at correct gestational age of 2,4,6 months were observed.Nursing knowledge and nursing skills,Self-rating Anxiety Scale (SAS) and Self-rating Depression Scale (SDS) scores of puerperae were observed in two groups on admission and at discharge.Breastfeeding rate,re-hospitalization rate,morbidity and mortality within 6 months were compared.Results The body weight,body length and head circumference were not statistically significant of two groups at birth and at corrected gestational age of 40 weeks (P ＞ 0.05),and they were heavier,and larger than those of the control group at corrected gestational age of 2,4 and 6 months (P ＜ 0.05).Breastfeeding rate in the study group was higher,morbidity rate and readmission rate were lower than that of the control group (P ＜ 0.05),but there was no significant difference in mortality of two groups (P ＞ 0.05).At discharge of NICU,mothers of premature infants had no statistically significant difference in nursing knowledge and skills (P ＞ 0.05),but they commanded more after 2 monthsof discharge (P ＜ 0.05),and study group improved more significantly (P ＜ 0.05).At discharge of NICU,SAS and SDS scores of infants'mothers were not statistically significant (P ＞ 0.0 5),but it was significantly decreased at 2 months of discharge (P ＜ 0.0 5),and study group decreased more (P ＜ 0.0 5).Conclusion Family-centered discharge guidance can increase the physical development of children,reduce the morbidity rate,and improve the family's bad mood,so it is worthy of clinical promotion.

Objective To explore effect of family-centered discharge guidance on family care of premature infants in NICU.Methods A total of 174 premature infants with extremely low birth weight in NICU were studied and were randomly divided into study group and control group,with 87 cases per group.Control group received conventional discharge guidance while the study group received family-centered discharge planning.Height and weight changes of neonates at discharge,and at correct gestational age of 2,4,6 months were observed.Nursing knowledge and nursing skills,Self-rating Anxiety Scale (SAS) and Self-rating Depression Scale (SDS) scores of puerperae were observed in two groups on admission and at discharge.Breastfeeding rate,re-hospitalization rate,morbidity and mortality within 6 months were compared.Results The body weight,body length and head circumference were not statistically significant of two groups at birth and at corrected gestational age of 40 weeks (P ＞ 0.05),and they were heavier,and larger than those of the control group at corrected gestational age of 2,4 and 6 months (P ＜ 0.05).Breastfeeding rate in the study group was higher,morbidity rate and readmission rate were lower than that of the control group (P ＜ 0.05),but there was no significant difference in mortality of two groups (P ＞ 0.05).At discharge of NICU,mothers of premature infants had no statistically significant difference in nursing knowledge and skills (P ＞ 0.05),but they commanded more after 2 monthsof discharge (P ＜ 0.05),and study group improved more significantly (P ＜ 0.05).At discharge of NICU,SAS and SDS scores of infants'mothers were not statistically significant (P ＞ 0.0 5),but it was significantly decreased at 2 months of discharge (P ＜ 0.0 5),and study group decreased more (P ＜ 0.0 5).Conclusion Family-centered discharge guidance can increase the physical development of children,reduce the morbidity rate,and improve the family's bad mood,so it is worthy of clinical promotion.

OBJECTIVE: To analyze the clinical characteristics and treatment effect between bilateral (bi-) and unilateral (uni-) sudden sensorineural hearing loss (SSNHL). METHOD: Four hundred and eighty cases of SSNHL were retrospective study, which were divided into two groups of bi-SSNHL (n = 40) and uni-SSNHL (n = 440). Clinical characteristics and treatment effects were compared of the two groups. RESULT: The incidence rate of bi-SSNHL was 8.3 percent and uni-SSNHL was 91.7 percent of all patients with SSNHL. Bi-SSNHL occurs more commonly in patients of old age, diabetes mellitus, and lipid panes abnormalities compared to uni-SSNHL. Twenty-eight ears in the bi-SSNHL group showed hearing recovery (35%), compared with 56.4 percent of patients with uni-SSNHL. CONCLUSION Bi-SSNHL and uni-SSNHL may have a completely different clinical characteristics and treatment effect, that implies a different pathophysiology and prognosis. Recognition their different clinical characteristics and treatment effect between bilateral and unilateral SSNHL can help in counseling and managing the patients and correctly evaluate the prognosis.
Adult ; Female ; Hearing Loss, Bilateral ; diagnosis ; therapy ; Hearing Loss, Sudden ; diagnosis ; therapy ; Hearing Loss, Unilateral ; diagnosis ; therapy ; Humans ; Male ; Middle Aged ; Prognosis ; Retrospective Studies ; Treatment Outcome

In addition to visual field defects, occipital lobe injury can also cause fundus changes, such as retinal nerve fiber layer atrophy, ganglion cell complex atrophy and even optic nerve atrophy, and these fundus changes have a good correlation with the visual field defect site. It is considered to be caused by transneuronal retrograde degeneration (TRD) of retinal ganglion cells secondary to occipital lobe injury. These changes can be detected by means of optical coherence tomography, fundus examination, magnetic resonance imaging, etc. Among them, optical coherence tomography is more sensitive than other examinations. Here, the anatomical basis of TRD, case reports, pathogenesis, auxiliary examination, treatment and prognosis of TRD secondary to occipital lobe injury are reviewd.

Objective To explore the effect of PRECEDE nursing model in elderly patients with chronic hepatitis B.Methods Eighty-six elderly patients with chronic hepatitis B in 302 military hospital from June 2015 to June 2016 were selected. The participants were divided into two groups according to the random number table. The intervention group received PRECEDE model nursing while the control group received routine nursing care. The therapeutic effect, compliance, and quality of life were compared between the two groups. Results The intervention group had significantly higher total effective rate compared with the control group (97.67% vs. 88.37%; χ2=6.604,P<0.05). The intervention group had better diet, exercise, compliance, smoking and drinking control, and regular review compared with the control group (P<0.05). There was no significant difference in the quality of life between two groups before the intervention (P>0.05). However, after the intervention, the body function, social function, psychological function, substance function and the total score of the quality of life were significantly higher in the intervention group compared with the control group (P<0.05).Conclusions PRECEDE model can significantly improve the liver function of elderly patients with chronic hepatitis B. It can promote patients' compliance and quality of life, which should be further developed in clinical practice.

Safety is the core of the quality of Chinese materia medica products， and microbial pollution caused by medicinal materials， decoction pieces， intermediate products and others can bring certain impact on the quality and safety of Chinese materia medica products. The reasons for this are not only the problems of medicinal materials themselves， but also the exogenous pollution introduced in the production process. How to effectively use microbial detection technology and establish an appropriate microbial quality control strategy in the whole process of Chinese materia medica production is of great significance to improve the quality of Chinese materia medica products. Therefore， the authors put forward a microbial quality control strategy in the whole process of Chinese materia medica production based on the guidance of quality by design （QbD） concept， emphasizing the scientific linkage between the internal and external microbial quality control systems to jointly ensure the quality of products in all aspects. Among them， the internal microbial quality control system includes the control of the whole chain of Chinese materia medica-decoction pieces-intermediate products-excipitents-packaging materials-final products， which should be carried out by stages and characteristics， while the external microbial quality control system includes the control of personnel-equipment and facilities-pharmaceutical water-environment， emphasizing the principle of quality risk management and the development of monitoring programs， aiming to closely integrate microbial quality risk management with the production process of Chinese materia medica products， and to classify and develop microbial control strategies in order to minimize the impact of contaminating microorganisms and effectively guarantee the quality of Chinese materia medica products.