ObjectiveTo evaluate the value of Token Test in testing Chinese aphasia and study the mechanism of bilateral hemispheric asymmetry.Methods33 patients with left hemispheric cerebral vascular diseases and 30 patients with right hemispheric cerebral vascular diseases were studied by Token Test and Aphasia Battery of Chinese(ABC). ResultsThe statistical analysis shows that the score of Token Test was significantly correlated with all tests of ABC in both left and right hemispheric damages groups(P<0.01), and that the score of Token Test was significantly negative correlated with infarction areas in left hemispheric damages groups (P<0.01),but incorrelated with infarction areas in right hemispheric damages groups(P>0.05). There is a significant correlation between the score of Token Test and the severity of the aphasia(P<0.01). Conclusions Token Test was closely related with ABC. It can be effective to detect some higher neuropsychological function disorder.

Objective To investigate the effect of high definition transcranial direct current stimulation(HD-tDCS)at different stim-ulation timings(online and offline)on finger motor skill learning in healthy adults. Methods From March to November,2022,31 right-handed male participants were recruited from Shenyang Sport Uni-versity and randomly assigned to three groups,who received online,offline or sham HD-tDCS respectively dur-ing the three-day sequential visual isometric pinch task learning process.The daily motor skill learning gains,to-tal motor skill learning gains and speed-accuracy function(SAF)were observed. Results The daily motor skill learning gains increased in all the groups,and it was the best in the online group(F=24.692,P<0.001);the learning gains were better in the online group than in the offline group(t=4.732,P<0.001)and the sham group(t=3.839,P=0.004)on the third day.The total motor skill learning gains were ranked as the online group=the offline group>the sham group.SAF data indicated that the online group outper-formed both the offline and sham groups. Conclusion HD-tDCS can promote the finger motor skill learning in healthy adults,and online HD-tDCS is more effec-tive.

OBJECTIVETo understand the association between the blood glucose levels of pregnant women in second trimester detected by 75 gram oral glucose tolerance test (OGTT) and the birth weight of neonates.

METHODSDemographic information collection and OGTT were conducted for 3 081 pregnant women at ≤14 gestational weeks and 24-28 gestational weeks respectively. Multiple logistic regression analysis was done to identify the factors associated with the birth weight and the risks of large for gestational age (LGA) in three levels (FPG, OGTT-1 h and OGTT-2 h) of OGTT percentile group, multiple linear regression analysis was used to evaluate the relationships between maternal glucose levels and neonate birth weight.

RESULTSPre-pregnancy obesity (24.0 kg/m2≤BMI<28.0 kg/m2) (OR=1.4, 95%CI:1.0-2.0, P=0.029) and gestational diabetes mellitus (OR=2.4,95% CI: 1.8-3.2, P<0.001) were the risk factors. Pre-pregnancy underweight (BMI<18.5 kg/m2) (OR=1.6, 95%CI: 1.2-2.2, P=0.003), preeclampsia (OR=4.0, 95%CI: 1.9-8.4, P<0.001) increased the risk for small for gestational age (SGA). Multiple linear regression analysis showed neonate birth weight was positive correlated with maternal glucose levels (β were 91.99, 33.60, 32.00, respectively, P<0.001). Percentile groups of each OGTT level was linearly positive associated with increased mean value of neonate birth weight, and so with the risk of LGA.

CONCLUSIONSThere were positive correlations between maternal glucose levels and neonate birth weight. The risk of LGA increased with the maternal glucose levels, but there was no statistical association between SGA and maternal glucose levels. FPG level is one of the predictors of LGA. Active surveillance and control of maternal glucose level can effectively reduce the risk of LGA.

Birth Weight ; Blood Glucose ; analysis ; Cohort Studies ; Diabetes, Gestational ; Female ; Glucose Tolerance Test ; Humans ; Infant, Newborn ; Infant, Small for Gestational Age ; Logistic Models ; Obesity ; Pre-Eclampsia ; Pregnancy ; Pregnancy Trimester, Second ; blood ; Risk Factors ; Thinness