Objective To study the adsorption function of macroporous resin for purifying the extract of Dayuan Dropping Pills and to investigate the purification process of Dayuan Dropping Pills by macro-porous adsorption resin. Methods Taking the content and the extraction rate of baicalin as the main standard index, and the adsorption characters as well as the purification capacities of eight types of macroporous adsorption resins,such as NKA-12, HPD-600, HPD-500, HPD-300, HPD-100, D101, AB-8,and NKA-9, used to treat baicalin of Dayuan Dropping Pills were investigated preliminarily. Results The appropriate adsorption conditions were: the concentration of baicalin was 2.65 mg/mL, flow rate was 3 BV/h, the effect of desorption was satisfactory when 50% alcohol (5 BV) and water (4 BV) were used as eluant. Conclusion HPD-300 resin can be applied to refine the Dayuan Droppingp Pills.

Objective To study the technology for purification of total alkaloids from Rhizoma Coptidis by maeroreticular adsorbent resin.Methods LD605,D101,DA201,NKA-9,and AB-8 types of macroreticular adsorbent resins werre used to separate and purify the total alkaloid from Rhizoma Coptidis.The yields and purities of the products were compared as indexes.Results AB-8 Type macroreticular adsorbent resin had optimum adsorption and elution parameters with its dynamic saturated adsorption ratio up to 1.23 mg/g.After eluted with 2 BV of distilled water and 2 BV 40% ethanol,the yields of total alkaloid was 85%,and content was 80%.Conclusion The AB-8 type macroreticular resin showsa better comprehensive adsorption property and can be used to separate and purify the total alkaloids from Rhizoma Coptidis.