ObjectiveTo explore the diagnosis value of color Doppler ultrasound of the carotid atherosclerosis plaques in diabetic patients. MethodsColor Doppler ultrasonic assessment of carotid was performed in 124 diabetic patients(test group)and 100 normal controls(control group).The intima-media thickness(IMT)and the carotid atherosclerosis plaques parameters were measured.The results were compared and analyzed between two groups. ResultsThe IMT and the incidence rate of carotid atherosclerosis plaques in the test group were higher than those in the control group(all P＜0.05).There was no statistical difference in the site of the plaques between test and control group(P＞0.05). ConclusionThe incidence rate of the carotid atherosclerosis of type 2 diabetes was higher.Carotid color Doppler ultrasonography was an optimal technique for screening and diagnosing atherosclerosis.

Objective To explore the clinical efficacy of percutaneous vertebroplasty technique(PVP) in the patients with senile osteoporotic thoracolumbar compression fractures (OVCFs) and to explore the main factors of PVP.Methods PVP treatment of OVCFs 46 cases,in the perspective of C-arm X-ray,bone cement as a filling material,transpedicular puncture and injection of 59 vertebrae.Results The pain in 35 cases(76.09％) OVCFs patients apparent ease or disappear,the remaining 11 cases of moderate relief;follow-up period(3 to 15)months(mean 8.6months).After X-ray review,the patient' s bone cement dispersion was good and has improved vertebral height has not been lost,activity and quality of life significantly inproved.Conclusion PVP is simple,less invasive,etc.,which can quickly reduce pain and improve their quality of life.

Liver transplantation rapidly has become the best choice for pediatric patients with end-stage and metabolic liver disease, since the first liver transplantation succeeded in 1989. In pediatric liver transplantation, significantly improved short-term and long-term survival is attributed to advances in surgical techniques and reasonable immunosuppression regimens in the last 20 years. However, postoperative infections, which remain the most common complication following pediatric liver transplantation, severely affect posttransplantation morbidity and mortality. This paper summarizes the infections after liver transplantation in children and rational drug use.

Objective To analyse subclavian steal syndrome(SSS)by transcrinial Doppler ultrasound (TCD)and to explore the rdationship between the different degrees of subelavian artery(SUBA)and the degree of steal blood vertebral artery and clinieal value of TCD.Methods Thirty seven patients of SSS were divided into three groups according to vdoeity of SUBA and direction of vertebral artery.The stenosis of SUBA and steal degree were compared.Results Mild and moderate stenosis of SUBA were found in 15 cases with no steal and stage Ⅰ steal in 12 cases(80%);Severe stenosis of SIJBA was found in 14 cases with no steal and stage Ⅰ steal in 3 cases(21%),with significant difference between the two groups(P＜0.05).In mild and moderate stenosis group,there were 3 cases of stage Ⅱ and Ⅲ steal(20%)while in severe stenosis group there were 11 cases of stage Ⅱ and Ⅲ steal (78%),among which,the signifieant difference(P＜0.05)was observed.Stage Ⅲ steal was found in 2 cases of severe stenosis group(14%)and 7 cases of occlusion group(87%),with significant difference(P＜0.05).10 cases were found to have bilateral SUBA stenoeis,including 1 case of bilateral steal.4 cases underwent digital subtraction angiography(DSA)which results were in accordance with the results of TCD.5 cases underwent CT angiography,the results of 3 of which were similar with TCD but 2 cases did not show any abnormality.Steal happened from vertebral artery(VA)-VA in 28 cases(75.6%)and basal artery(BA)-VA in 9 cases(24.4%).Conclusion TCD could be used to diagnose SSS and the degree of steal blood.The degreo of SUBA stenosis is related to degree of vertwbral artery steal.

The American College of Gastroenterology( ACG)released the first clinical guideline for drug-induced liver injury( DILI)in June,2014:the diagnosis and management of idiosyncratic drug-induced liver injury( IDILI), which includes all aspects of IDILI,such as risk factors,diagnosis,differential diagnosis and treatment. The guideline discusses especially the issues on herbal and dietary supplements( HDS)induced liver injury and DILI in patients with chronic liver disease. The guideline is of great value for standardizing the clinical diagnosis and treatment,providing the best recommendations for management of the patients with DILI. Since the evidence of research in the field of DILI is relatively weak at this moment,the clinicians should consider the possible individual difference of the patients under the frame of guideline for making the best clinical decision.

BACKGROUND:Bone grafting is often needed in posterolateral lumbar spinal fusion, but bone mass is often not enough to finish this operation. Part of the autologous iliac bones from patients are needed to take as supplement. OBJECTIVE:To investigate the safety and effectiveness of application of nano-hydroxyapatite/colagen/ poly(L-lactide) for posterolateral lumbar spine fusion. METHODS:The clinical data of 52 patients with lumbar degenerative disease who had received the treatment in Meishan Orthopedics Hospital of Sichuan Province, China during February 2013 to February 2014 were retrospectively analyzed. The patients al received posterolateral lumbar spine fusion with bone grafts made of autologous iliac bone particles and nano-hydroxyapatite/colagen/poly(L-lactide). RESULTS AND CONCLUSION:Among the 52 patients, wound healing by primary intention occurred in 51 patients, increased skin temperature, skin sweling, pains and fluid leaking were not observed. The lumbar spine function and pain symptoms of patients al improved to different degrees after internal fixation, The posterolateral lumbar spine fusion rate was 13%, 54% and 84% at 3, 6 and 12 months after internal fixation respectively, and there was no pseudarthrosis. During the 12 months of folow-up period, no screw loose or displacement , adjacent segment slippage or displacement were observed in any patient. These results suggest that the application of nano-hydroxyapatite/colagen/poly(L-lactide) for posterolateral lumbar spine fusion can achieve good results. The nano-hydroxyapatite/colagen/poly(L-lactide) bone graft material is highly biocompatible and safe.

ObjectiveTo investigate the clinical efficacy of primary and connecting point combination acupuncture in treating mild and moderate depression.MethodPatients meeting the inclusion criteria were randomly allocated to observation and control groups. Both groups of enrolled patients took fluoxetine hydrochloride (Prozac). The observation group received meridian-unblocking acupuncture at yuan-primary points and luo-connecting points and the control group, acupuncture at routinely selected points in the eleventh-five textbook. Treatment was given for four consecutive weeks. The Hamilton Depression Scale (HAMD) 24-item score was recorded in the patients before and after one month of treatment. The therapeutic effects were evaluated according to the score reduction rate in the two groups.ResultThere wasa statistically significant post-treatment difference in the HAMD 24-item score between the two groups (P<0.05). The total efficacy rate was83.3% in the treatment group and70.0% in the control group. There was a statistically significant post-treatment difference in therapeutic effect between the two groups (P<0.05). ConclusionMeridian-unblocking acupuncture at yuan-primary points and luo-connecting points is more effective than conventional acupuncture in proving the symptoms in patients with mild or moderate depression.

Objective:To explore therapeutic effect of rosuvastatin and atorvastatin treatment on levels of lipoprotein and inflammatory factors in patients with acute coronary syndrome (ACS) .Methods :A total of 74 ACS patients , who were treated in our department of cardiology from Mar 2008 to Feb 2014 ,were selected .According to random number table ,they were randomly and equally divided into rosuvastatin group and atorvastatin group .Therapeutic effect on 24d after administration ,levels of low density lipoprotein cholesterol (LDL‐C) ,high density lipoprotein cholesterol (HDL‐C) ,interleukin (IL)‐18 and C reactive protein (CRP) before and four weeks after treatment were compared between two groups .Results:On 24d after treatment ,total effective rat of rosuvastatin group was significantly higher than that of atorvastatin group (83.8% vs .75.7% , P< 0.05);after four‐week treatment , compared with atorvastatin group ,there were significant reductions in levels of LDL‐C [ (1. 8 ± 0. 2 ) mmol/L vs . (1.4 ± 0.1) mmol/L] ,IL‐18 [ (1.8 ± 0.2) vs .(1.4 ± 0.1)] and CRP [ (1.9 ± 0.3) pg/ml vs .(1.4 ± 0.2) pg/ml],andsignificantriseinHDL‐Clevel[(1.4±0.2)mmol/Lvs.(1.9±0.3)mmol/L]inrosuvastatingroup,P<0.05 all .Conclusion:Rosuvastatin therapy can achieve better adjusting lipid and anti‐inflammation effect than those of atorvastatin in patients with acute coronary syndrome ,which is worth clinical extending .

Current definition of apnea of prematurity (AOP) with the time of breathing cease equal or more than 20 seconds,or less than 20 seconds accompanying with bradycardia and(or) cyanosis was absence of strong clinical evidence and arbitrary.We have no consensus on the treatment of AOP,but severe AOP will lead to the intermittent hypoxic episodes(IHE) and severe fluctuation of oxygen saturation associated with severe retinopathy of prematurity and bad neurodevelopmental outcome.IHE occurred not only due to AOP,but also in the processes of continuous positive airway pressure and invasive ventilation.Decreasing the IHE is one of key problems of preterm respiratory support.Optimal target oxygen saturation should be regulated dynamically,the target oxygen saturation of 90％ ～ 95％ lowers IHE and mortality,but likely increases retinopathy of prematurity.Caffeine,the first choice of AOP,may be no of effect in the mixed or obstructive AOP which may need more respiratory support to reduce the lung volume loss and airway resistance.

Objective To explore the clinical value of Thinprep cytology test (TCT)combined with h -TERC and c -myc in the diagnosis of cervical cancer.Methods hTERC amplification was detected by dual -color interphase fluorescence in situ hybridization (FISH),and the results were compared with TCT and histological examination.Examination the positive which TCT,h -TERC and c -myc by pathological examination.The final diag-nosis was determined by the pathological examination.Results TCT was abnormal in 26.4% of 500 case,18.0%abnormal h -TERC gene,16.0% abnormal c -myc gene.In 270 cases according to the cervical biopsy,the positive rate of chronic inflammation,cervical intraepithelial neoplasia (CIN)Ⅰ,CINⅡ,CINⅢ and cervical cancer:44.4%, 38.2%,36.4%,18.2%,and 7.3% respectively.The positive rates of h -TERC were 18.1%,45.4%,52.5%, 65.9% and 100.0%,respectively.The positive rates of c -myc were 21.4%,48.9%,56.7%,59.9% and 100.0%.With increased pathological grade,the expressions of h -TERC and c -myc were high.Conclusion TCT combined with h -TERC and c -myc can test cervical cancer more effective.