1.Experience of financial toxicity in cancer patients: a Meta-synthesis of qualitative researches
Jihua TAO ; Mingying YANG ; Manyu XIAO ; Yuqin LIU ; Danna LI ; Tingrui MENG ; Siya XIA
Chinese Journal of Modern Nursing 2024;30(17):2288-2295
Objective:To systematically integrate qualitative researches on the financial toxicity experience of cancer patients, so as to provide reference for formulating intervention strategies for financial toxicity in cancer patients.Methods:Qualitative studies on financial toxicity experience of cancer patients were searched in Web of Science, PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure, VIP, Wanfang data, and China Biology Medicine disc, with a search period from database establishment to August 31, 2023. The quality of the included literature was evaluated using the quality evaluation criteria for qualitative research of the Joanna Briggs Institute Evidence Based Health Care Center in Australia. The aggregation integration method was used to integrate the results.Results:A total of 12 articles were included, and 68 research results were extracted and categorized into 15 new categories. Four integrated results were obtained, including anxiety and stress under financial difficulties, relying on family members to start a new in adversity, and dancing together with treatment and life to write a new article, and great expectations for the future.Conclusions:Pay attention to the financial toxicity of cancer patients, actively seek response strategies, and bring benefits to cancer patients.
2.Comparative study of left atrial matrix ablation and posterior wall linear isolation ablation strategies in elderly patients with atrial fibrillation
Hui Xiao ; Haoyang Lu ; Manyu Dai ; Yangcheng Xue ; Zhuoran Jia ; Zhuoran Jia ; Jie Guo ; Ren Zhao
Acta Universitatis Medicinalis Anhui 2022;57(11):1844-1848
Objective :
In the present study,the changes of left atrial matrix characteristics and the effect of cathe- ter ablation on cardiac function in elderly patients with persistent atrial fibrillation were observed.Furthermore,the application of two catheter ablation methods including circular pulmonary vein isolation combined with left atrial ma- trix modification or left atrial posterior wall isolation were compared by researchers in order to explore effectiveness and safety of the two methods in elderly persistent atrial fibrillation patients.
Methods :
A total of 86 elderly pa- tients with persistent atrial fibrillation were selected and divided into two groups using randomization principle ; the pulmonary vein isolation combined with left atrial matrix modified catheter ablation method was named matrix modi- fied group (43 cases) ; the pulmonary vein isolation combined with left atrial posterior wall isolation catheter abla- tion method was named posterior wall isolation group (43 cases) .During ablation left atrial electro matrix mapping were analyzed by multipole catheter for all patients.After ablation all patients were follow-up in 12 months by car- diac color doppler ultrasound examination,ECG and Holter.The incidence of arrhythmia ,serious adverse event and complications were compared between two groups. Successful rate of single ablation and blank period recur- rence after ablation were observed in 12 months follow-up time.
Results :
Through electrogram mapping of left atri- um low-voltage areas or scar areas were founded in 72 cases among the 86 cases after ablation,After a 12-month follow-up,the incidence of arrhythmia in the blank period between the two groups was 41.9% ( matrix modified group) and 23. 3% (posterior wall isolation group) ,independently,P<0. 01,successful rates of single ablation in the two groups were 83. 7% (matrix modified group) ,60. 5% (posterior wall isolation group) ,independently, P <0. 01 .No adverse event occurred in the two groups.After AF ablation LVEF increased,LVEDD and LVAD significantly decreased in all of the cases.There was no significant difference between the two groups in patients ’ characters ablation time and complications rate.
Conclusion
Circular pulmonary vein isolation combined with left atrial matrix modification is as safe as left atrial posterior wall isolation,and it is a simplified,personalized,and more effective ablation strategy in elderly patients with persistent atrial fibrillation.