Non-Hodgkin's lymphoma (NHL) constitutes a group of malignancies those arises from cellular components of lymphoid or extranodal tissues. The head and neck is the most common area for the presentation of these lymphoproliferative disorders. Primary involvement of salivary glands is uncommon. This report described a case of a 73-year-old female patient who presented with involvement of both nodal and extranodal sites, with predominant involvement of salivary glands. The tumor staging worked up along with imaging, histopathological, and immunohistochemical findings were discussed. Computed tomographic images showed the involvement of Waldeyer's ring, larynx, orbit, and spleen. This report described imaging and prognostic tumor markers in diagnosing, treatment planning, and prognosis.
Biomarkers, Tumor ; Female ; Head ; Humans ; Larynx ; Lymphoma, Large B-Cell, Diffuse ; Lymphoma, Non-Hodgkin ; Lymphoproliferative Disorders ; Neck ; Neoplasm Staging ; Orbit ; Prognosis ; Salivary Glands ; Spleen