1.A Case of Ruptured Thoracoabdominal Aortic Aneurysm Repair under Profound Hypothermia Using Subclavian Arterial Perfusion through Right Axillo-Bifemoral Bypass Graft Implanted Ten Years Previously
Kenji Mogi ; Yoshiharu Takahara ; Shigeyasu Takeuchi ; Manabu Sakurai
Japanese Journal of Cardiovascular Surgery 2004;33(4):263-265
A 74-year-old woman had undergone right axillo-bifemoral bypass for infrarenal aortic stenosis due to aortitis syndrome in another hospital. She was admitted as an emergency case to our hospital with a ruptured thoracoabdominal aortic aneurysm, and an emergency operation was performed. We used arterial cannulation to the artificial vascular graft implanted for axillo-bifemoral bypass and first cooled the body temperature to below 25°C, then dissected the aorta. In the case of ruptured descending and thoracoabdominal aortic aneurysm, profound hypothermia is a valuable adjunct for unexpected blowout rupture during the preparation of the aneurysm and spinal cord and visceral protection.
2.Endoscopic Findings and Treatment of Gastric Neoplasms in Familial Adenomatous Polyposis
Chihiro SATO ; Kazuya TAKAHASHI ; Hiroki SATO ; Takumi NARUSE ; Nao NAKAJIMA ; Masafumi TAKATSUNA ; Ken-ichi MIZUNO ; Satoru HASHIMOTO ; Manabu TAKEUCHI ; Junji YOKOYAMA ; Masaaki KOBAYASHI ; Shuji TERAI
Journal of Gastric Cancer 2022;22(4):381-394
Purpose:
Gastric neoplasia is a common manifestation of familial adenomatous polyposis (FAP). This study aimed to elucidate the clinical characteristics, endoscopic features including fundic gland polyposis (FGPsis), and treatment outcomes of gastric neoplasms (GNs) in patients with FAP.
Materials and Methods:
A total of 35 patients diagnosed with FAP, including nine patients from four pedigrees who underwent esophagogastroduodenoscopy (EGD), were investigated regarding patient characteristics, GN morphology, and treatment outcomes.
Results:
Twenty-one patients (60.0%) had 38 GNs; 33 (86.8%) and 5 (13.2%) were histologically diagnosed with adenocarcinoma and adenoma, respectively. There were no specific patient characteristics related to GNs.Nodule-type GNs were more prevalent in patients with FGP than without (52.2% vs. 0.0%, P=0.002) in the upper body of the stomach. Conversely, depressed-type GNs were fewer in patients with FGPsis than in those without (13.0% vs. 73.3%, P<0.001). Slightly elevated-type GNs were observed in both groups (34.8% vs. 20.0%, P=0.538). Even within pedigrees, the background gastric mucosa and types of GNs varied. In total, 24 GNs were treated with endoscopic submucosal dissection (ESD) and eight with endoscopic mucosal resection (EMR). EMR was selected for GNs with FGPsis because of the technical difficulty of ESD, resulting in a lower en bloc resection rate (62.5% vs. 100%, P=0.014).
Conclusions
Our study indicates the necessity of routine EGD surveillance in patients diagnosed with FAP. Notably, the morphology and location of GNs differed between patients with and without FGPsis. Endoscopic treatment and outcomes require more attention in cases of FGPsis.