From 3/1999 to 11/2001, 27 patients (age 6-48, 15 males and 12 females) with AML (21 denovo, 4 relape, 2 biphenotype) were treated with induction chemotherapy of 7-3-5 protocol at the blood transfusion and hematology center HCM city. 81.5% (22/27) patients were complete remission but one died on 32th due to fungal infection of the lung, 7.4% patients had no remission, 11.1% patients induction deaths due to infection and GVHD after transfusion. Neutrophil recovery > 0.5x 109/l by allocated treatment is 17 days and platelet > 100x 109/l is 18 days. CR of 7-3-5 protocol is higher than 7-3 protocol. Toxicity of drug is the same.
Leukemia, Erythroblastic, Acute ; therapy ; therapeutics