1.A case of combined pregnancy following IVF-ET.
Man Chul PARK ; Chi Seok AHN ; Seok Hyun KIM ; Shin Yong MOON ; Jin Yong LEE ; Yoon Seok CHANG
Korean Journal of Obstetrics and Gynecology 1991;34(10):1457-1462
No abstract available.
Pregnancy*
2.Evaluation of shear bond strengths of gingiva-colored composite resin to porcelain, metal and zirconia substrates.
Hong Seok AN ; Ji Man PARK ; Eun Jin PARK
The Journal of Advanced Prosthodontics 2011;3(3):166-171
PURPOSE: The purpose of this study is to evaluate and compare the shear bond strength of the gingiva-colored composite resin and the tooth-colored composite resin to porcelain, metal and zirconia. MATERIALS AND METHODS: Sixty cylindrical specimens were fabricated and divided into the following 6 groups (Group 1-W: tooth-colored composite bonded to porcelain, Group 1-P: gingiva-colored composite bonded to porcelain, Group 2-W: tooth-colored composite bonded to base metal, Group 2-P: gingiva-colored composite bonded to base metal, Group 3-W: toothcolored composite bonded to zirconia, Group 3-P: gingiva-colored composite bonded to zirconia). The shear bond strength was measured with a universal testing machine after thermocycling and the failure mode was noted. All data were analyzed using the two-way analysis of variance test and the Bonferroni post-hoc test at a significance level of 0.05. RESULTS: The mean shear bond strength values in MPa were 12.39, 13.42, 8.78, 7.98, 4.64 and 3.74 for Group 1-W, 1-P, 2-W, 2-P, 3-W and 3-P, respectively. The difference between the two kinds of composite resin was not significant. The shear bond strength of Group 1 was the highest and that of Group 3 was the lowest. The differences among Group 1, 2 and 3 were all significant (P<.05). CONCLUSION: The shear bond strength of the gingiva-colored composite was not less than that of the tooth-colored composite. Thus, repairing or fabricating ceramic restorations using the gingiva-colored composite resin can be regarded as a practical method. Especially, the prognosis would be fine when applied on porcelain surfaces.
Ceramics
;
Collodion
;
Dental Porcelain
;
Prognosis
;
Zirconium
3.Localized Trichorrhexis Nodosa Arising From Habitual Rubbing.
Duk Kyu CHUN ; Sang Man PARK ; Jae Ju JO ; Ho Chul CHOI ; Sang Mee SEOK
Annals of Dermatology 1999;11(4):232-235
Trichorrhexis nodosa(TN) denotes small node-like swelling with a loss of cuticle of the hair shaft through which the hair readily fractures. The basic cause of TN is mechanical or chemical trauma, and a contributing factor is an inherent weakness of the hair shaft. We report a case of localized TN in a 37-year-old male. He had an ovoid hair patch with multiple small white-gray dotted and stubby hairs localized to the right occipital scalp. TN is known to be the commonest of all hair shaft anomalies (Price, 1975). However TN is rarely reported, and there have been only four reports in Korean dermatological literature, to our knowledge, which might be due to underdiagnosis of this disorder. We postulated that diagnostic difficulty lies in the discrepancy between terminology and gross morphological findings.
Adult
;
Fibrinogen
;
Hair
;
Humans
;
Male
;
Scalp
4.Analysis of DNA Ploidy Pattern of Hepatocellular Carcinoma with Comparison between Flow Cytometric and Image Cytometric Study.
Sung Sook KIM ; Seok Gun PARK ; Dong Sun HAN ; Man Ha HUH
Korean Journal of Pathology 1992;26(1):1-9
Fifty cases of hepatocellularcarcinoma were studied using retrospective flow cytometric(FCM) and image cytometric(ICM) DNA analysis to determine the prevalence of aneuploid cell population and whether they were associated with any particular clinico-pathologic findings. At the same time, we compared the difference between FCM and ICM. The materials were prepared from 50 micrometer cut of paraffin embedded blocks. The DNA modal values, which could be defined in 42 cases by FCM with 74% aneuploidy and in 50 cases by ICM with 76% aneuploidy. So 95% of the cases had concordant DNA ploidy results by both techniques of FCM and ICM. Abnormal DNA pattern was correlated with age(<50), presence of cirrhosis, pathologic grade and some pathologic types(p<0.05), but was not correlated with presence of HBsAg, sex, alphafeto protein, and alcohol history(p>0.05). Also we found that ICM technique was easier to perform and interprete.
Carcinoma, Hepatocellular
5.Hrombosed Aortic Dissections and Aortic Aneurysms: MRI Findings and Differential Diagnosis.
Jin Wook CHUNG ; Jae Hyung PARK ; Man Chung HAN ; Gi Seok HAN ; Yong Kyu YOON
Journal of the Korean Radiological Society 1994;30(5):853-858
PURPOSE: MRI is known to be an effective imaging modality of the aorta and its role is steadily increasing in the evaluation of acquired aortic diseases including aortic dissections and aortic aneurysms. However, differentiation of the aortic dissections with thrombosed false lumen from the aortic aneurysm with mural thrombus in MRI has not been easy. Therefore, the authors tried to find the characteristic MR featrses which would to differentiate the two diseases. MATERIALS AND METHODS: MR images of 6 patients with thrombosed aortic dissection and 7 patients with thrombosed aortic aneurysms were reviewed retrospectively and compared in regand to shape and extent of thrombus, dimension of aorta, and luminal flow signal. RESULTS: Thrombosed aortic dissections showed sharply demarcated crescent shaped aortic wall thickening of even thickness involving long segment of the aorta, whereas thrombosed aortic aneurysms showed irregular aortic wall thickening of uneven thickness localized in the short dilated segment of the aorta. Characteristically aortic aneurysm with mural thrombus showed eccentric intraluminal slow flow signal. In contrast to the signal void of the true lumen in aortic dissections, the residual lumen of the aortic aneurysm with mural thrombus revealed intraluminal signal due to slow flow. CONCLUSION: Familiarity to these MRI findings of thrombosed aortic dissections and aortic aneurysms may lead to the accurate differential diagnosis in majority of cases.
Aorta
;
Aortic Aneurysm*
;
Aortic Diseases
;
Diagnosis, Differential*
;
Humans
;
Magnetic Resonance Imaging*
;
Phenobarbital
;
Recognition (Psychology)
;
Retrospective Studies
;
Thrombosis
6.An experimental study on renal artery embolization using absolute ethanol, with special emphasis on infusionrate
Joon Koo HAN ; Young Seok LEE ; Byung Ihn CHOI ; Jae Hyung PARK ; Man Chung HAN
Journal of the Korean Radiological Society 1984;20(3):361-365
Transcatheter embolization using absolute ethanol is a widely used technic in interventional radiology. Butits mechanism of action and embolization effect on various infusion speed are poorly understood. Authors performedan experimental study in rabbits to doccument the effect of absolute ethanol onvarious infusion rate. The resultsare as follows; 1. In high speed infusion group(>0.1ml/sec. n=13), 11 cases showed peripheral obstruction and 2 cases showed central obstruction. 2. In low speed infusion group(<0.1ml/sec. n=12), 4 cases showed peripheralobstruction and 8 cases showed central obstruction (p<0.02). 3. On follow-up angiography performed 4 weeks later(n=8), no demonstrable significant differences are found between two groups.
Angiography
;
Ethanol
;
Follow-Up Studies
;
Rabbits
;
Radiology, Interventional
;
Renal Artery
7.Proteomic Analysis of a Rat Cerebral Ischemic Injury Model after Human Cerebral Endothelial Cell Transplantation.
Tae Min CHOI ; Misun YUN ; Jung Kil LEE ; Jong Tae PARK ; Man Seok PARK ; Hyung Seok KIM
Journal of Korean Neurosurgical Society 2016;59(6):544-550
OBJECTIVE: Cerebral endothelial cells have unique biological features and are fascinating candidate cells for stroke therapy. METHODS: In order to understand the molecular mechanisms of human cerebral endothelial cell (hCMEC/D3) transplantation in a rat stroke model, we performed proteomic analysis using 2-dimensional electrophoresis and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Protein expression was confirmed by quantitative real-time PCR and Western blot. RESULTS: Several protein spots were identified by gel electrophoresis in the sham, cerebral ischemia (CI), and CI with hCMEC/D3 treatment cerebral ischemia with cell transplantation (CT) groups, and we identified 14 differentially expressed proteins in the CT group. Proteins involved in mitochondrial dysfunction (paraplegin matrix AAA peptidase subunit, SPG7), neuroinflammation (peroxiredoxin 6, PRDX6), and neuronal death (zinc finger protein 90, ZFP90) were markedly reduced in the CT group compared with the CI group. The expression of chloride intracellular channel 4 proteins involved in post-ischemic vasculogenesis was significantly decreased in the CI group but comparable to sham in the CT group. CONCLUSION: These results contribute to our understanding of the early phase processes that follow cerebral endothelial cell treatment in CI. Moreover, some of the identified proteins may present promising new targets for stroke therapy.
Animals
;
Blotting, Western
;
Brain
;
Brain Ischemia
;
Cell Transplantation
;
Cell- and Tissue-Based Therapy
;
Electrophoresis
;
Endothelial Cells*
;
Fingers
;
Humans*
;
Ischemia
;
Mass Spectrometry
;
Neurons
;
Proteomics
;
Rats*
;
Real-Time Polymerase Chain Reaction
;
Stroke
;
Transplants
8.Time Point Expression of Apoptosis Regulatory Proteins in a Photochemically-Induced Focal Cerebral Ischemic Rat Brain
Hyung Seok KIM ; Man Seok PARK ; Jeong Kil LEE ; Hye Jeong KIM ; Jong Tae PARK ; Min Cheol LEE
Chonnam Medical Journal 2011;47(3):144-149
Apoptosis after global or focal cerebral ischemia plays a crucial role in mediating cell death. In this study, we observed the time point expression of physiologic events involving apoptosis regulatory proteins after photochemically-induced focal cerebral ischemia in Sprague-Dawley rats. Protein expression was evaluated at days 1, 3, and 7 by Western blot. Bcl-2, Bax, caspase-3, and phosphorylated Akt (pAkt) activity markedly increased in the ischemic hemisphere in a time-dependent manner, not affected. The expression of Bcl-2, Bax, and caspase-3 was dramatically changed around day 3, whereas changes in pAkt expression occurred at day 1. Differential elevation of these apoptosis regulatory proteins at various time points indicates that different modes of cell death occur in photochemically-induced focal cerebral ischemia in a rat brain.
Animals
;
Apoptosis
;
Apoptosis Regulatory Proteins
;
Blotting, Western
;
Brain
;
Brain Ischemia
;
Caspase 3
;
Cell Death
;
Negotiating
;
Rats
;
Rats, Sprague-Dawley
;
Rose Bengal
9.The Effect of Sympathetic Blocks in the Prevention of Postherpetic Neuralgia.
Woo Seok KOH ; Sang Man PARK ; Band Soon KIM ; Dong Yeop SHIN
Korean Journal of Dermatology 1997;35(4):620-626
BACKGROUND: Many investigators have advocated neural and especially regional sympathetic blockade for acute herpe. zoster pain. Some believe that nerve blocks not only relieve acute pain but also, if given early in the course of clinical disease, prevent progression to postherpetic neuralgia. OBJECTIVE: The purpose of this study was to evaluate the preventive effect of sympathetic blockade on herpes zoster METHODS: Fifteen patients with herpes zoster were treated with sympathetic blocks according to the severity of pain. RESULTS: The total score of pain degree decreased from 3.4 to 1.1 with sympathetic blocks in 15 patients in 2 months. Sympathetic blocks prevented or relieved postherpetic neuralgia in more than 90% of patients treated within 2 weeks of the onset of the acute phase of the disease and in more than 85% of patients over 60. CONCLUSION: Sympathetic blocks are effective in preventing postherpetic neuralgia if applied soon after the onset of the acute phase of herpes zoster.
Acute Pain
;
Herpes Zoster
;
Humans
;
Nerve Block
;
Neuralgia, Postherpetic*
;
Research Personnel
10.A Case of Wernicke's Encephalopathy Associated with Hyperemesis Gravidarum.
Korean Journal of Perinatology 2006;17(1):84-88
Wernicke's encephalopathy, characterized by ataxia, nystagmus, confusion, due to thiamine deficiency, can be a lethal disease without appropriate treatment such as thiamine supplement. The thiamine defect could be from poor oral intake because of hyperemesis gravidarum as well as alcoholic disease. Radiologically, Wernicke's encephalopathy presents the abnormality around the 3rd and the 4th ventricle and periaqueductal area. We now present the case of Wernicke's encephalopathy associated with hyperemesis gravidarum with the radiologic finding and reviewing other literature.
Alcoholics
;
Ataxia
;
Female
;
Humans
;
Hyperemesis Gravidarum*
;
Pregnancy
;
Thiamine
;
Thiamine Deficiency
;
Wernicke Encephalopathy*