1.Erratum: Panton-Valentine Leukocidin Positive Staphylococcus aureus Isolated from Blood in Korea.
Jae Seok KIM ; Jeong Su PARK ; Wonkeun SONG ; Han Sung KIM ; Hyoun Chan CHO ; Kyu Man LEE ; Eui Chong KIM
The Korean Journal of Laboratory Medicine 2008;28(6):498-498
This erratum is being published to correct the printing error on page 286 of the article entitled 'Panton-Valentine leukocidin positive Staphylococcus aureus isolated from blood in Korea' by Kim JS, Park JS, Song W, Kim HS, Cho HC, Lee KM, Kim EC in Korean J Lab Med 2007;27:286-91. DOI 10.3343/kjlm. 2007.27.4.286 as follows. The heading of the right column of the Table 1 was misprinted as methicillin-resistant, so it should be corrected to methicillin-susceptible.
Adult
;
Amino Acid Substitution
;
Brain Neoplasms/radiotherapy/surgery
;
Breast Neoplasms/diagnosis/radiotherapy/surgery
;
Female
;
*Genetic Counseling
;
Genetic Predisposition to Disease
;
*Germ-Line Mutation
;
Humans
;
Li-Fraumeni Syndrome/*diagnosis/genetics/therapy
;
Mutation, Missense
;
Pedigree
;
Tumor Suppressor Protein p53/*genetics
2.Risk Factors for Endothelial Cell Loss after Phacoemulsification: Comparison in Different Anterior Chamber Depth Groups.
Yang Kyeung CHO ; Hwa Seok CHANG ; Man Soo KIM
Korean Journal of Ophthalmology 2010;24(1):10-15
PURPOSE: To assess the risk factors for endothelial cell loss after phacoemulsification with implantation of intraocular lens according to anterior chamber depth (ACD). METHODS: This prospective study included 94 eyes of 94 patients undergoing phacoemulsification cataract surgery. To assess the risk factors for corneal endothelial cell loss, we examined seven variables at 1 day, 1 week, 6 weeks, and 12 weeks postoperatively in each ACD-stratified group. RESULTS: Multiple linear regression analysis showed that the only variable influencing the percentage decrease in corneal endothelial cell density throughout the postoperative follow-up period in the long ACD group (ACD III) was nucleosclerosis. The variables influencing the percentage decrease in corneal endothelial cell density in the short ACD group (ACD I) at one day and one week postoperatively were corneal incisional tunnel length and nucleosclerosis. CONCLUSIONS: Risk factors for endothelial cell loss after phaoemulsification were different according to ACD. Long corneal tunnel length can be one of the risk factors for endothelial cell loss in short ACD eyes.
Anterior Chamber/ultrasonography
;
Cataract/ultrasonography
;
Cataract Extraction/*methods
;
Cornea/pathology/surgery
;
Corneal Endothelial Cell Loss/*etiology
;
Humans
;
Lens Implantation, Intraocular
;
Phacoemulsification/*adverse effects/methods
;
Prospective Studies
;
Risk Factors
3.An Assessment of Adolescent Internet Addiction Problems Related to Depression, Social Anxiety and Peer Relationship.
Myung Soo LEE ; Eun Young OH ; Sun Mi CHO ; Man Jei HONG ; Jae Seok MOON
Journal of Korean Neuropsychiatric Association 2001;40(4):616-628
OBJECTIVE: The purpose of this study was to survey the present conditions of adolescents' Internet use and to investigate the relations of Internet addiction to depression, social anxiety and problems in peer relationship. METHOD: Eight hundred and sixty-nine high-school students(male/female=371/498) were included in the study, each of whom completed a standard questionnaire related to Internet use determined. We assessed internet addiction and depressive symptoms of adolescents using Youngs Internet Addiction Scale and the Beck Depression Inventory(BDI), respectively. Social Avoidance and Distress Scale were employed to measure social anxiety and avoidance. Fear of Negative Evaluation-Brief Scale was for fear of negative evaluation by other people. An Index of Peer relation was devoted to problems in peer relationships. Chi-square test and ANOVA were used to identify the present conditions of Internet addiction and to analyze the relations of Internet addiction with depression, social anxiety and problems in peer relationship. RESULTS: 1) Of these 869 subjects, 371(42.7%) were male students and 498(57.3%) were female. The mean age was 16.27 years(SD=0.82) and there was no significant difference between two sex groups. 2) Of these 869 subjects, 291(33.4%) showed addictive tendency and among them 18 subjects(2.07%) were classified into obvious addiction group. In this study, we defined upper 30% of Internet addiction scores as 'addiction group' and lower 30% as 'normal control group'. 3) Male students had significantly higher mean scores of Internet addiction scale than females and there was significantly higher rates of male students in addiction group. 4) Comparing two groups, there was no statistically significant difference in terms of the preferred types of Internet media, although addiction groups tended to use chatting and E-mail more, normal control group tended to use information search more. And there was no significant difference regarding games on the Internet. 5) There was more depressive tendency in line with more sensitive response against negative-evaluation and more problems of peer relationship in addiction group. However, there was no significant difference regarding anxiety on social situation. CONCLUSION: Compared to previous studies, findings from this study showed that the rates classified as the group of obvious Internet addiction were relatively lower. However, including those who had tendency of Internet addiction, about 30% of all subjects had problems related to Internet use. In addition, depression or relationship problems were triggered more severely in Internet addiction group. With these findings in mind we finally suggest that therapeutic approach to comorbid psychopathology as well as Internet addiction itself should be required.
Adolescent*
;
Anxiety*
;
Depression*
;
Electronic Mail
;
Female
;
Humans
;
Internet*
;
Male
;
Psychopathology
;
Surveys and Questionnaires
4.Effects of Leadership Styles of Nursing Managers on Turnover Intention of Hospital Nurses:A Systematic Review and Meta-Analysis
Yunjeong CHO ; Seok Hee JEONG ; Hee Sun KIM ; Young Man KIM
Journal of Korean Academy of Nursing 2022;52(5):479-498
Purpose:
This study aimed to examine effect sizes of leadership styles of nursing managers on turnover intention of hospital nurses.
Methods:
A systematic review and meta-analysis were conducted in accordance with the PRISMA and MOOSE guidelines. Participants were nurses working in hospitals. The intervention involved nursing managers’ leadership styles; the outcome assessed was nurses’ turnover intention. This was an observational study design. Eleven databases were searched to obtain articles published in Korean or English. Of the 14,428 articles reviewed, 21 were included in systematic review and meta-analysis. Comprehensive Meta-Analysis and R software programs were used.
Results:
The total effect size r (ESr) was - 0.25 (95% confidence interval: - 0.29 to - 0.20). Effect sizes of each leadership style on turnover intention were as follows: ethical leadership (ESr = - 0.34), transformational leadership (ESr = - 0.28), authentic leadership (ESr = - 0.23), transactional leadership (ESr = - 0.21), and passive avoidant leadership (ESr = 0.13). Ethical leadership was the most effective style in decreasing turnover intention of hospital nurses.
Conclusion
Positive leadership styles of nurse managers effectively decrease turnover intention of hospital nurses, and negative leadership styles of nurse managers effectively increase turnover intention of hospital nurses. The ethical leadership style is the most effective in decreasing turnover intention of hospital nurses; however, it requires careful interpretation as its effects are reported by only two studies. This study contributes to addressing the high turnover rate of hospital nurses and developing positive leadership styles of nurse managers in hospital settings.
5.A case of brain metastasis of papillary thyroid carcinoma.
In Kyu KIM ; Yeon Heoi CHO ; Man Seok PARK ; Myeong Kyu KIM ; Ki Hyun CHO ; Sei Jong KIM
Journal of the Korean Neurological Association 1997;15(3):707-711
Papillary thyroid carcinoma(PTC), the commonest thyroid malignancy, has a good prognosis and low incidence of distant metastasis. Brain metastasis from PTC are extremely rare. The frequency of it reported as 0.1% to 5% in several reported series. A 24 year-old man noted a mass in his neck at 19 years of age. The diagnosis of PTC was made by the biopsy of the mass. Total thyroidectomy, postoperative internal radiation and daily 400w thyroxine therapy was done. The tonic contraction of the right leg evolving to secondary generalized seizure was noted at the age of 24 years old. A brain MRI showed Ix1cm enhancing mass in the left frontal lobe without perilesional edema. The brain mass was removed by the CRW-guided stereotactic surgery. The brain metastasis of PTC was confirmed histopathologically.
Biopsy
;
Brain*
;
Diagnosis
;
Edema
;
Frontal Lobe
;
Humans
;
Incidence
;
Leg
;
Magnetic Resonance Imaging
;
Neck
;
Neoplasm Metastasis*
;
Prognosis
;
Seizures
;
Thyroid Gland*
;
Thyroid Neoplasms*
;
Thyroidectomy
;
Thyroxine
;
Young Adult
6.Isolation of Healthcare-Associated Pathogens from Cellular Phones Used by Medical Personnel.
Jae Seok KIM ; Oh Kun KWON ; Wonkeun SONG ; Han Sung KIM ; Ji Young PARK ; Hyoun Chan CHO ; Kyu Man LEE ; Hae Ran LEE
Korean Journal of Nosocomial Infection Control 2010;15(1):36-40
BACKGROUND: Cellular phone has become a necessary device for communicating in hospitals. Cellular phones contaminated with bacteria may serve as a fomite in the transmission of pathogens by the hands of medical personnel. We investigated the bacterial contamination of cellular phones used by medical personnel in a tertiary hospital. METHODS: Culture swabs were obtained from 101 cellular phones and 99 anterior nasal cavities from medical personnel using cellular phones. The swabs were inoculated on blood agar, MacConkey agar, mannitol salt agar, and enterococcal broths containing 6microgram/mL vancomycin for 48 h at 37degrees C. The bacteria were identified on the basis of colony morphology, gram staining characteristics, catalase test, coagulase test, and DNase test; Microscan (Siemens, USA) was used for the identification of enterococci. RESULTS: Of the 101 cellular phones, 13 were contaminated with Staphylococcus aureus (including 4 methicillin-resistant S. aureus [MRSA]), 61 with coagulase-negative staphylococci (CoNS) (including 38 methicillin-resistant CoNS), 27 with Micrococcus spp., 11 with diphtheroids, 67 with Bacillus spp., and 4 with viridans streptococci. No gram-negative bacilli were isolated. Nasal swabs yielded 36 S. aureus, including 9 MRSA. Only 1 of 9 cellular phones used by the MRSA carriers was contaminated with MRSA. CONCLUSION: Cellular phones used by some medical personnel were contaminated with pathogens such as S. aureus or MRSA. Although, the clinical implications of pathogens isolated from cellular phones have not been fully investigated, pathogens could be transmitted by the hands of medical personnel who are cellular phone users.
Agar
;
Bacillus
;
Bacteria
;
Catalase
;
Cellular Phone
;
Coagulase
;
Deoxyribonucleases
;
Disinfection
;
Fomites
;
Hand
;
Hand Hygiene
;
Mannitol
;
Methicillin Resistance
;
Methicillin-Resistant Staphylococcus aureus
;
Micrococcus
;
Nasal Cavity
;
Staphylococcus aureus
;
Tertiary Care Centers
;
Vancomycin
;
Viridans Streptococci
7.Antimicrobial Resistance Profiles of Staphylococcus aureus Isolated in 13 Korean Hospitals.
Jae Seok KIM ; Han Sung KIM ; Wonkeun SONG ; Hyoun Chan CHO ; Kyu Man LEE ; Eui Chong KIM
The Korean Journal of Laboratory Medicine 2004;24(4):223-229
BACKGROUND: There has been a nationwide increase in infections caused by Staphylococcus aureus resistant to multiple antimicrobial agents in Korea. Although nationwide antimicrobial resistance pro-files have been reported recently by analysing routine antimicrobial test results, a more extensive resistance profile survey including those agents that are not used routinely is required for the inferring the mechanism of antimicrobial resistance. We assessed the resistance profiles of a variety of antimicrobial agents on Korean nationwide collection of S. aureus strains and analyzed the profiles according to methicillin resistance. METHODS: We collected a total of 253 clinical isolates of S. aureus from 13 clinical laboratories over the country during a month in 2002. Antimicrobial susceptibility testings were performed with 21 antimicrobial agents by disk diffusion method. Methicillin-resistant S. aureus (MRSA) isolates were also confirmed by the PCR detection of mecA gene. RESULTS: More than 90% of MRSA strains were resistant to the following antimicrobial agents tested: -lactams (92.0-98.3%), gentamicin (92.5%), tobramycin (94.9%), erythromycin (96.6%), and cip-rofloxacin (94.3%). But only 0-29% of methicillin-susceptible S. aureus (MSSA) strains were resistant to those agents. MRSA and MSSA strains were respectively resistant to chloramphenicol in 4.0% and 2.5%, rifampin in 12.1% and 1.3%, trimethoprim-sulfamethoxazole in 22.4% and 1.3%, and amikacin in 51.7% and 3.8%. No isolates were resistant to vancomycin and teicoplanin. Falsely susceptible results against beta-lactams in MRSA ranged from 1.7-7.5%. No significant differences in susceptibility were noted against the agents within the same classes such as macrolide and fluoroquinolone. The PCR results of mecA gene correlated 100% with the results of oxacillin disk diffusion test. CONCLUSIONS: Methicillin resistance in S. aureus was an indication of resistance against beta-lactams, gentamicin, tobramycin, macrolide, and fluoroquinolone in Korea. However, MRSA still retained the susceptibility to chloramphenicol, rifampin, and trimethoprim-sulfamethoxazole. This study may provide antimicrobial resistance profiles necessary for the understanding of antimicrobial resistance mechanisms of S. aureus.
Amikacin
;
Anti-Infective Agents
;
beta-Lactams
;
Chloramphenicol
;
Diffusion
;
Erythromycin
;
Gentamicins
;
Korea
;
Methicillin Resistance
;
Methicillin-Resistant Staphylococcus aureus
;
Oxacillin
;
Polymerase Chain Reaction
;
Rifampin
;
Staphylococcus aureus*
;
Teicoplanin
;
Tobramycin
;
Trimethoprim, Sulfamethoxazole Drug Combination
;
Vancomycin
8.Correlations between Neurologic and Psychiatric Symptoms in Acute Stroke Patients.
Hee Ju KANG ; Kyung Yeol BAE ; Sung Wan KIM ; Jae Min KIM ; Il Seon SHIN ; Man Seok PARK ; Ki Hyun CHO ; Jin Sang YOON
Korean Journal of Psychosomatic Medicine 2012;20(2):98-104
OBJECTIVES: This study aimed to investigate the correlations between neurological and psychiatric symptoms at two weeks after stroke. METHODS: For 412 stroke patients, stroke severity was evaluated by the National Institutes of Health Stroke Scale (NIHSS), disability by the Barthel Index(BI) and modified Rankin Scale(mRS), cognitive function by the Korean Mini-Mental State Examination(K-MMSE), and muscle power by grip strength. Psychiatric symptoms were assessed by Symptom check list-90-Revision(SCL-90-R), consisted of nine symptom domains : Somatization, Obsessive-compulsive, Interpersonal sensitivity, Depression, Anxiety, Hostility, Phobic anxiety, Paranoid ideation, Psychoticism, and Additional items. The correlations between the neurological and psychiatric symptoms were investigated at the time of admission and before discharge(i.e. before and after treatment). RESULTS: At the time of admission, NIHSS score was associated with scores on Phobic anxiety and Additional items ; and scores on BI and mRS were associated with Depression, Phobic anxiety and Additional items. At the time of discharge, NIHSS score was associated with scores on Somatization, Depression, Phobic anxiety, and Additional items ; scores on BI and mRS were associated with scores on Depression, Phobic anxiety and Additional items ; MMSE score was associated with Obsessive-compulsive, Depression, Phobic anxiety, and Additional items ; and grip strength was associated with Somatization, Depression, Anxiety and Additional items. CONCLUSIONS: More severe neurological symptoms were associated with higher psychiatric morbidity particularly in depression, phobic anxiety, sleep and appetite disturbance at acute stage of stroke. More intensive psychiatric care and intervention are needed for the high risk group.
Anxiety
;
Appetite
;
Depression
;
Hand Strength
;
Hostility
;
Humans
;
Muscles
;
National Institutes of Health (U.S.)
;
Neurologic Manifestations
;
Stroke
9.Molecular Epidemiology of Methicillin-Resistant Staphylococcus aureus Isolates with Toxic Shock Syndrome Toxin and Staphylococcal Enterotoxin C genes.
Jae Seok KIM ; Han Sung KIM ; Wonkeun SONG ; Hyoun Chan CHO ; Kyu Man LEE ; Eui Chong KIM
The Korean Journal of Laboratory Medicine 2007;27(2):118-123
BACKGROUND: Many methicillin-resistant Staphylococcus aureus (MRSA) isolates in Korea possess a specific profile of staphylococcal enterotoxins in that the toxic shock syndrome toxin gene (tst) coexists with the staphylococcal enterotoxin C gene (sec). Because the analysis of staphylococcal cassette chromosome mec (SCCmec), a mobile genetic element mecA gene encoding methicillin resistance, showed that majority of these are SCCmec type II, these MRSA isolates with tst and sec may be genetically related with each other. This study was performed to investigate the genetic relatedness of tstand sec-harboring MRSA strains isolated in Korea by using pulsed-field gel electrophoresis (PFGE). METHODS: A total of 59 strains of MRSA isolates of SCCmec type II possessing tst and sec were selected for PFGE and phylogenetic analyses. These isolates were collected from 13 health care facilities during nationwide surveillance of antimicrobial resistance in 2002. RESULTS: The 59 MRSA isolates were clustered into 11 PFGE types, including one major group of 26 strains (44.1%) isolated from 7 healthcare facilities. Seven PFGE types contained 2 or more isolates each, comprising 55 isolates in total. CONCLUSIONS: Most of SCCmec type II MRSA isolates containing tst and sec showed closely related PFGE patterns. Moreover, MRSA isolates collected from different healthcare facilities showed identical PFGE patterns. These findings suggested a clonal spread of MRSA strains possessing tst and sec in Korean hospitals.
Bacterial Toxins/*genetics
;
Chromosomes, Bacterial
;
Electrophoresis, Gel, Pulsed-Field
;
Enterotoxins/*genetics
;
Humans
;
Methicillin Resistance/*genetics
;
Phylogeny
;
Staphylococcal Infections/epidemiology/microbiology
;
Staphylococcus aureus/drug effects/*genetics/isolation & purification
;
Superantigens/*genetics
10.Accidental epidural injection of ephedrine: A case report.
Hyun seok CHO ; Man jo KIM ; Mun Cheol KIM ; Dong jun LEE
Korean Journal of Anesthesiology 2008;55(1):104-106
We report a case of accidental epidural ephedrine injection. A 29-year-old male with left femoral artery occlusion was scheduled for thromboembolectomy. The operation was performed under epidural anesthesia. During the operation, ephedrine (30 mg/6 ml) was accidentally injected through epidural catheter instead of ropivacaine (45 mg/6 ml). Following the incident, we injected normal saline (10 ml) in the epidural space to dilute the solution. The patient had no complaint but blood pressure rose to 165/115 mmHg transiently. We observed the patient closely in recovery room and no further complication was found. In previous reports, various attempts have been tried to manage such incidents, but no definitive treatment for accidental injection is known. We present this case to remind the importance of confirming the drug everytime before injection.
Adult
;
Amides
;
Anesthesia, Epidural
;
Blood Pressure
;
Catheters
;
Ephedrine
;
Epidural Space
;
Femoral Artery
;
Humans
;
Injections, Epidural
;
Male
;
Recovery Room