In this study, 45 parotid glands and 111 facial nerves were examined in adult Korean cadavers to determine the morphological relationship of the parotid gland and the peripheral facial nerve. The results are summarized below; (1) The average length of the parotid gland was 54.7mm and the width averaged 32.9mm, and the gland was slightly larger in males. (2) The shape of the parotid gland was classified into four types and the series contained 66.7% type A, 15.5% type B, 8.9% type C and 8.9% type D. Type A was the most common type. (3) The patterns of tributory ducts into Stenson's duct were divided into 5 types and the series showed 42.2% type a, 26.7% type b 4.4% type c, 4.4% type d, 22.3% type e. The frequency of occurrence of accessory glands was 22%. (4) The average distance from the external angle of the mandible to the bifurcation of the facial nerve trunk was 28.8mm. (5) A pattern of trifurcation of the main facial nerve trunk was discovered in 4.4% of the cases. (6) The pattern of anastomosis of the peripheral branches of the facial nerve was classified into six types, and the rate of occurrence of each type was type I 6.3%, type II 13.5 %, type III 33.4%, type IV 23.4%, type V 6.3%, type VI 17.1%.
Adult ; Facial Nerve/anatomy & histology* ; Female ; Human ; Korea ; Male ; Mongoloid Race* ; Parotid Gland/anatomy & histology* ; Sex Factors

There were many studies to investigate the pathogenesis and prevention of infection in artificial joint replacement due to the difficulty in management of infected arthroplasty in spite of using large amounts of antibiotics. Biomaterials play a major role in the development of infection because of the way the body responds to their chemical and physical characteristics. Exopolysaccharide glycocalyx or biofilm(slime) which is produced by organisms adhered to the biomaterials has been detected and regarded as an important factor in pathogenesis. The production of slime on the biomaterials in turn makes the pathogens resistant to the antibiotics and therefore they survive. The objects of this study are to evaluate which materials are more susceptible to the adherence by Staphylococcus epidermidis, to evaluate the amount of antibiotics needed to kill the S. epidermidis adhered to the biomaterials(Polymethymethacrylate, Titanium-6Aluminum-4Vanadium alloy, Ultrahigh molecular weight polyethylene), and to evaluate the timing of administration of the antibiotics(cephradine, gentamicin) and potadine for prevention of postoperative infection. The results are as follows. 1. The materials in order of greatest adherence due to the number of organisms colonized are poly- methylmethacrylate(PMMA), ultrahigh molecular weight polyethylene(UHMWPE), and titanium alloy(Ti-6A1-4V alloy) being the least adherent. 2. With the production of biofilm the S. epidermidis becomes resistant to even that of 4 times the minimum bactericidal concentration(MBC) of antibiotics. 3. For prevention of postoperative infection, the prophylactic administration of cephradine if effective when used within 4 hours after contamination and the gentamicin and potadine are effective when used within 8 hours after the contamination with S. epidermidis.
Alloys ; Anti-Bacterial Agents ; Arthroplasty ; Biocompatible Materials ; Biofilms ; Cephradine ; Colon ; Gentamicins ; Glycocalyx ; Joints ; Molecular Weight ; Staphylococcus epidermidis ; Titanium

No abstract available.
Humans ; Quality of Life*

Sparganosis is a parasitic infestation caused by the larval stage of Spirometra erinacei. Human infection results from ingestion of raw or undercooked flesh of any of the numerous intermediate hosts and from application of such flesh as poultices. Sparganosis have been reported from orbit and bulbar conjunctiva. But, urogenital infestation of Sparganum is rarely observed. We report an additional case of the sparganum infestation in the right scrotum.
Conjunctiva ; Eating ; Humans ; Orbit ; Scrotum* ; Sparganosis* ; Sparganum ; Spirometra

BACKGROUND: Photographic imaging is a valuable tool in Dermatology. Analog cameras have been used for many years for documenting such images. However, with the recent introduction of the digital camera, dermatologists have begun to replace analog images for digital images when recording dermatologic and histologic findings. We employed a continuous quality improvement (CQI) activity to achieve this goal to replace the image recording system. METHODS: A CQI team composed of all the department members was formed to begin digitalization, Problems caused during digitalization were discussed during monthly meetings. RESULT: 1. We could achieve improvements of image management efficacy. 2. There was a reduction of management space. 3. There was a reduction of costs seen in the total expenses of preparing photographic documentation. CONCLUSION: After digitalization of clinical and histological dermatologic imaging, we were able to reduce expenses, use storage spaces more efficiently, and reduce production time. When considering the efficiency of hospital management, these results are very encouraging, and it can be stated that these results are a good outcome of CQI activities.
Dermatology ; Quality Improvement*

BACKGROUND: Eicosanoids are metabolites of arachidonic acid that are rapidly biosynthesized and degraded during inflammation, and their metabolic changes reveal altered enzyme expression following drug treatment. We developed an eicosanoid profiling method and evaluated their changes on drug treatment. METHODS: Simultaneous quantitative profiling of 32 eicosanoids in liver S9 fractions obtained from rabbits with carrageenan-induced inflammation was performed and validated by liquid chromatography-mass spectrometry coupled to anion-exchange solid-phase purification. RESULTS: The limit of quantification for the devised method ranged from 0.5 to 20.0 ng/mg protein, and calibration linearity was achieved (R 2>0.99). The precision (% CV) and accuracy (% bias) ranged from 4.7 to 10.3% and 88.4 to 110.9%, respectively, and overall recoveries ranged from 58.0 to 105.3%. Our method was then applied and showed that epitestosterone treatment reduced the levels of all eicosanoids that were generated by cyclooxygenases and lipoxygenases. CONCLUSIONS: Quantitative eicosanoid profiling combined with in vitro metabolic assays may be useful for evaluating metabolic changes affected by drugs during eicosanoid metabolism.
Animals ; Carrageenan/toxicity ; *Chromatography, High Pressure Liquid/standards ; Cytokines/blood ; Disease Models, Animal ; Eicosanoids/*analysis/metabolism/standards ; Inflammation/etiology/metabolism ; Male ; Rabbits ; Reference Standards ; Solid Phase Extraction ; *Tandem Mass Spectrometry/standards

Renal tubular dysfunctions have been observed in hydronephrosis, resulting in metabolic acidosis, hyperkalemia and excessive free water diuresis. These findings are occasionally found in infant and children. Batle et al. first reported distal tubular acidosis associated with low potassium excretion resulting from aldosterone resistance in adults with obstructive uropathy. We have experienced a case of transient hyperkalemia and hyperaldosteronism secondary to hydronephrosis in 63-year-old female patient. The causes of hyperkalemia were examined under the impression of secondary adrenal insufficiency due to corticosteroid abuse or hyporeninemic hypoaldosteronism due to diabetic nephropathy. But it proved to be resulted from hyperaldosteronism due to hydronephrosis. The hyperkalemia resulting from hyperaldosteronism is rare in adults. It may result from aldosterone resistance at distal nephron due to obstructive uropathy or the defect of distal nephron in hydrogen and potassium secretion in the distal nephron rather than from aldosterone deficiency. After she underwent percutaneous nephrostomy, serum potassium was maintained within normal range. She performed total cystectomy with ureterocutaneostomy in purpose for treatment of bladder cancer. So we report this case with a review of literature.
Acidosis ; Adrenal Insufficiency ; Adult ; Aldosterone ; Child ; Cystectomy ; Diabetic Nephropathies ; Diuresis ; Female ; Humans ; Hydrogen ; Hydronephrosis* ; Hyperaldosteronism* ; Hyperkalemia* ; Hypoaldosteronism ; Infant ; Middle Aged ; Nephrons ; Nephrostomy, Percutaneous ; Potassium ; Reference Values ; Urinary Bladder Neoplasms ; Water

BACKGROUND: Takayasu's arteritis is a chronic non-specific inflammatory disease of arteries and it is known that aorta and its major branches are most commonly invoved. Its etiology is still unknown but the basic process is marked intimal proliferation, fibrosis and fibrous scarring with degeneration of the elastic fibers of the media. The proliferative and cicatrical process leads to luminal narrowing, stenosis, localized aneurysm, postsenotic dilatation and calcification in the involved arterial wall. Little attention has been paid to the diagnostic value of transesophageal echocardiography(TEE) in Takayasu's arteritis. METHODS: We evaluated transesophageal echocardiographic findings of aortic lesions in 3 cases of Takayasu's arteritis. RESULTS: The transesophageal echocardiographic findings of aortic lesions in Takayasu's arteritis characteristically showed relatively long sehmental luminal narrowing caused by marked intimal proliferation and contracture fo aortic wasll. The morphology of intimal thickening was characteristically circumferential, concentric and the size of the aorta itself was decreased by contracture as compared with atherosclerotic changes involving aorta. Besides these findings were consistent with angiographic findings. The common types of Takayasu's arteritis which we will meet clinically are known as type I or III. Indeed, 3 cases described in this paper are all type 3 patients. According to that fact, most of Takayasu's arterits may have aortic lesions that could be easily accessible by TEE and the degree of deformity of the aorta can be evaluated using TEE. CONCLUSION: The transesophageal echocardiography may be a valuable diagnostic tool for the evaluation of aortic wall and luminal status in the patients with Takayasu's arteritis.
Aneurysm ; Aorta ; Arteries ; Cicatrix ; Congenital Abnormalities ; Constriction, Pathologic ; Contracture ; Dilatation ; Echocardiography* ; Echocardiography, Transesophageal ; Elastic Tissue ; Fibrosis ; Humans ; Phenobarbital ; Takayasu Arteritis*

BACKGROUND: Coronary artery disease(CAD) has been related to a number of factors, including diabetes, smoking,hypertension, blood lipids, and family history of CAD. However, a few studies have examined the correlation between these factors and severity of CAD. In the present study, we aimed to define the correlation between risk factors and the severity of CAD. METHODS: The study population was 309 consecutive patients who underwent coronary angiography in Kang Nam St. Marys hospital between Mar. 1992 and Aug. 1994. We analyzed risk factors of CA ; age, total cholesterol(TC), triglyceride, high density lipoprotein cholesterol(HDL-C), low density lipoprotein cholesterol cholesterol(LDL-C), the ratio of TC to HDL-C, Lp(a), uric acid, fibrinogen, diabetes, hypertension, smoking, and family history of CAD. All films were reviewed without specific knowledge of blood laboratory results. Significant occlusive disease was defined as >50% diameter obstruction of a major coronary vessel. Extent of disease was defined as the number of major coronalry arteries with significant occlusive disease. RESULTS: 1) Statistically significant risk factors between one vessel disease group and multivessel disease group are age, TC, LDL-C, and diabetes in total patients and age, LDL, and diabetes in male patients. But there is no significant difference in female patients. 2) In patients with multivessel disease, age, HDL-C level are significantly lowere, and TG level and the percentage of smkoing are significantly higher, in male than female. 3) There is increase in four major risk factors(diabetes, hypertension,smoking,hypercholesterolemia) with the increased number of diseasesd coronary arteries; normal coronary group has 1.07 risk factors, one vessel disease group 1.30, two vessel disease group 1.49, and three vessel disease group 1.78. 4) In total and male patients, three independent variables are significantly associated with severity of CAD. These variables are age, smoking, and diabetes. In female patients, diabetes in only significant independent risk factor. CONCLUSION: The significant independent risk factors associated with severity of CAD are age, diabetes, and smoking in total and male patients. Whereas in female patients, diabetes is only significant independent risk factor.
Arteries ; Cholesterol, LDL ; Coronary Angiography ; Coronary Artery Disease* ; Coronary Vessels* ; Female ; Fibrinogen ; Humans ; Hypertension ; Lipoproteins ; Male ; Risk Factors* ; Smoke ; Smoking ; Triglycerides ; Uric Acid

Primary mucinous cystic cystadenomas of the retroperitoneum are very rarely encountered, and there have been only about 30 cases reported in the literature. The histogenesis of primary mucinous cystadenomas is unclear. Most authors suggested that it develops through mucinous metaplasia in a pre-existing mesothelium-lined cyst. Complete surgical excision is the only treatment and it is required for the final diagnosis and cure. We present here a case report of a 38-year-old Korean woman with primary retroperitoneal cystadenoma. It was a thin-walled, multilocular cyst with a dominant loculus that measured 10.0 X 7.5 X 5.5 cm3 in size, and to the best of our knowledge, this is the first such case to be reported in in Korea.
Adult ; Cystadenoma, Mucinous/*diagnosis/surgery ; Female ; Humans ; Retroperitoneal Neoplasms/*diagnosis/surgery