1.Liver Function Test in Congestive Heart Failure in Children.
Journal of the Korean Pediatric Society 1988;31(1):48-57
No abstract available.
Child*
;
Estrogens, Conjugated (USP)*
;
Heart Failure*
;
Humans
;
Liver Function Tests*
;
Liver*
3.Morphological and Biochemical Study on the Processes of Apoptosis Induced by Radiation.
Kye Yong SONG ; Seong Man KANG ; Seong Hwan HA ; Sang Chul PARK
Korean Journal of Pathology 1996;30(9):819-829
Transglutaminase(TGase) is a calcium dependent enzyme that catalyse and acyl transfer reaction forming epsilon-(gamma-glutamyl)-lysine cross linkage. the major known effect of TGase is its important role in the programmed cell death manifested in the granular layer of the skin and acidophilic bodies in the viral hepatitis and neoplastic processes. The enzyme activity, immunohistochemical reaction using polyclonal antibodies against cytosolic TGase C, light and electron microscopic studies and TdT staining of the transplanted fibrosarcoma cells in C3H mouse with radiation therapy were done. The presence of TGase was detected immunohistochemically by avidin-biotin peroxidase complex (ABC) method Apoptosis were significantly induced after irradiation dependent with time factors and irradiation doses, resulted in marked and confluent tumor cell loss. Highest activity of the cytosolic form of TGase was noted at 24 hours and decrease after then while membrane bounded form of the TGase showed no significant changes. Immunohistochemical staining revealed strong positive reaction in the sarcoma cells in diffuse fasion and around the necrotic foci in the cytoplasm. Terminal dideoxynucleotidyl transferase(TdT) staining revealed increasing numbers of apotptic cells from two hours after irradiation. In the mechanism of decreasing tumor size and cell death in radiation therapy, apoptosis plays an important role and during that process transglutaminse might do some irreversible cross-linking effects of cytoplasmic proteins causing cell death in part.
Mice
;
Animals
4.Two cases of Klippel-Treaunay-Weber Syndrome.
Chang Suk SEO ; Jae In RHO ; Young Su KWON ; Man Chul HA ; Jin Young JUNG
Journal of the Korean Pediatric Society 1990;33(4):553-558
No abstract available.
5.Two Cases of Congenital Asplenia.
Man Chul HA ; Young Tak LIM ; Hi Joo CHUN ; Hi Ju PARK ; Chan Yung KIM
Journal of the Korean Pediatric Society 1987;30(8):916-921
No abstract available.
6.The Two Cases of Klippel-Trenaunay Weber Syndrome.
Man Chul HA ; In Hun LEE ; Yong Tak LIM ; Hi Joo CHUN ; Hi Ju PARK ; Chan Yung KIM
Journal of the Korean Pediatric Society 1988;31(3):391-397
No abstract available.
Brain Stem Infarctions*
7.A clinical and bacteriologic study of infants and children with urinary tract infection.
Jae In ROH ; Yeong Su KWON ; Hung Kun OH ; Jin Hee JEONG ; Man Chul HA ; Jin Yeong JEONG
Journal of the Korean Pediatric Society 1991;34(1):57-65
No abstract available.
Child*
;
Humans
;
Infant*
;
Urinary Tract Infections*
;
Urinary Tract*
8.The new approach to maxillary and mandibular anterior dental arch forms : In Korean normal occlusion models.
Man Hee HA ; Woo Sung SON ; Hoon Chul YANG
Korean Journal of Orthodontics 2001;31(3):347-355
Maxillary and mandibular anterior dental arches often have the problems of occlusal relation and esthetics by malformations of teeth, congenital missing, et al. Though the clinician usually use the anterior ratio to overcome this problems, he has the limitation of a direct application this ratio to the prediction of anterior occlusal relationship by the change of anterior ratio as dental arch form, intercanine width, segment depth and arch perimeter. So this study examine maxillary and mandibular anterior dental arch forms by least square method using Korean normal occlusion models(man : 20 casts, woman : 20 casts). Maxillary and mandibular anterior dental arches of Korean normal occlusion models are curve fitted to polynomial function, beta function, hyperbolic cosine function in order. And this accuracy of curve fitting is constant regardless of man/woman and maxilla/mandible. The relationships between intercanine width, segment depth, and arch perimeter based on this curve fitted dental arch form are acquired. This relationships will give the prediction of anterior dental arch form and the information of more accurate anterior ratio according to intercanine width.
Dental Arch*
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Esthetics
;
Female
;
Humans
;
Tooth
9.Job Performance of Occupational Health Personnel.
Yun Chul HONG ; Eun Hee HA ; Kyung Ja JUN ; Young Man RHO ; Hye Sook PARK ; Heui Sug JO ; Hun Jae LEE ; Mi Ran YANG
Korean Journal of Occupational and Environmental Medicine 1997;9(3):496-507
No abstract available.
Occupational Health*
10.Osteogenic Differentiation of Mesenchymal Stem/Progenitor Cells Developed in Cultures from Human Umbilical Cord Blood.
Sung Eun YANG ; Man Kyoung LEE ; Yoon Sun YANG ; Chul Won HA
Journal of Korean Orthopaedic Research Society 2003;6(1):89-98
PURPOSE: To demonstrate the existence in human umbilical cord blood (hUCB) of circulating mesenchymal stem/progenitor cells(MSPC), the adherent cells developed in cultures from hUCB were characterized and induced to differentiate into osteoblasts. MATERIALS AND METHODS: Fifty hUCB harvests were cultured in the media supplemented with 10% fetal bovine serum. Homogeneously adherent fibroblast-like cells obtained during successive subcultivation were characterized by immunophenotyping analysis and induced to differentiate into osteoblasts. Reverse transcription-polymerase chain reaction of osteogenic markers, alkaline phosphatase (ALP) stain, and von Kossa stain were performed. RESULTS: The adherent fibroblast-like cells developed in cultures from hUCB positively expressed the MSPCrelated antigens, but, did not express the hematopoietic, HLA-DR, osteoclast, or endothelial antigens. These cells were well proliferated during successive subcultivation. Under osteogenic condition, these cells showed increased levels of osteogenic mRNAs and strong positivity in ALP and von Kossa stains at 4th week. CONCLUSION: The homogeneous fibroblast-like cells developed in cultures from hUCB were considered to be MSPC. Morphological and immunophenotypical characteristics of these cells were very similar to those of bone marrow-derived MSPC, and well differentiated into osteoblasts.
Alkaline Phosphatase
;
Coloring Agents
;
Fetal Blood*
;
HLA-DR Antigens
;
Humans*
;
Immunophenotyping
;
Osteoblasts
;
Osteoclasts
;
RNA, Messenger
;
Umbilical Cord*