Botulinum toxin A (BTX-A) was used in adult cerebral palsy patients for chronic pain treatment. Five patients (quadriplegia 3, diplegia 1, and athetosis 1 with an average age of 47) were all classified as GMFCS level IV. As a treatment for neck and trunk muscle pain, BTX-A injections were administered with a total dose below 6 units per kilogram of body weight. To investigate the efficacy of BTX-A, the Visual Analogue Scale and Modified Tsui Scale were used to evaluate the patients before and at regular monthly follow-ups after their injections. We found significant improvement in the Visual Analogue Scale scores at 1 month after initial injection and also found the same difference at the second injection. Also, although we found improvement in the Modified Tsui Scale scores at 1 month after injection, these improvements did not last as long as the Visual Analogue Scale improvements. BTX-A has been used in a growing number of indications for the treatment of muscle spasticity including blepharospasm, facial spasm and spasmodic torticollis. We found that BTX-A may also be useful in treating patients with cerebral palsy suffering from chronic pain.

We experienced a case of delayed-onset Wallenberg's syndrome following cervical spine fracture coexisting with suspected conversion disorder. A 69-year-old man was involved in a traffic accident, and was admitted to our rehabilitation unit for the purpose of posttraumatic rehabilitation. At first, he complained of right occipital and nuchal pain. But his complaints changed to ataxia, dysphagia and a suspected brainstem lesion four months after the accident. His brainstem MRI showed a small ischemic lesion in the right dorsolateral area of the medulla oblongata. The long time lag between the original traumatic event and his changing complaints made the diagnosis difficult. Accordingly, rehabilitation assessment and conventional rehabilitation approaches were prepared for all of his symptoms. The dysphagia and ataxia were gradually reduced and the hemiparesis lessened and disappeared. A couple of points were suggested by this case. The first is “We must never overlook a change of neurological symptom masked as conversion disorder, and never deny what the patient says without careful listening.” The second is “We should offer the patient a conventional rehabilitation program without the option for malingering and falsification. This case might suggest that our attitude toward so-called gray-zone cases has an influence on the functional/social prognosis.

A consensus meeting on autoimmune pancreatitis (AIP) was held in Seoul on August 31, 2007. Many Korean and Japanese gastroenterologist interested in AIP participated in the joint symposium, and issues related to histology, radiology, clinical manifestation, serology, and diagnostic criteria were discussed. This joint meeting indicated the need for unified diagnostic criterion for AIP in Korea and Japan. Here, we provide a summary of the symposium presentations and discussions.
Asian Continental Ancestry Group ; Consensus ; Humans ; Japan ; Joints ; Korea ; Pancreatitis

We examined the influence of hot water extract of coix seed (Coix lacryma-jobi L. var. ma-yuen Stapf) with husks on facial skin. Ten females (28-58 years old) took hot water extract of coix seed with husks 1 g/day for 8 weeks, and various skin parameters were measured. The results showed that the total amount of subsurface reflection of blue light, which is an index of skin translucency, increased significantly after 8 weeks of intake (p = 0.011). In addition, skin texture improved significantly after 4 and 8 weeks of intake (p = 0.007, p = 0.042). Additionally, the condition of tape-stripped stratum corneum also indicated significant improvement after 4 and 8 weeks intake (p = 0.0002, p = 0.020). These results suggested that the hot water extract of coix seed with husks exhibited effects even at 1 g/day, which is less than in previous reports.