1.Comparison of Dietary Macro and Micro Nutrient Intake between Iranian Patients with Long-term Complications of Sulphur Mustard Poisoning and Healthy Subjects
Mahdi Balali-Mood ; Marzie Zilaee ; Majid Ghayour-Mobarhan ; Mohammad Sobhan Sheikh-Aandalibi ; Hossein Mohades-Ardabili ; Hamideh Dehghani ; Gordon Ferns
Malaysian Journal of Medical Sciences 2014;21(6):19-26
Background: Patients with long-term complications of sulfur mustard (SM) poisoning are often less able to undertake optimum levels of physical activity and adequately control their dietary intake. The aim of present study was to investigate the dietary intake of patients with SM poisoning in comparison to a control group.
Methods: The study was undertaken on 55 Iranian male veterans, who had > 25% disabilities due to long-term complications of SM poisoning and 55 men age-matched healthy subjects. A previously validated food frequency questionnaire (FFQ) was used for measuring dietary macro/micro nutrient intake for both groups; and the results were analysed using Dietplan6 software.
Results: Analysis of macro/micro nutrients in dietary intakes of the patients versus the controls showed a significantly lower intake of several nutrients including selenium and carbohydrate. On the other hand, the dietary intake of trans-fatty acids and iodine were significantly higher in these patients.
Conclusion: Long-term complications of SM poisoning in the Iranian veterans induce both chemical and physical disabilities. Macro/micro nutrient intake in these patients was significantly different in comparison with matched, healthy subjects. Dietary advice for these patients should be strongly recommended to these patients in order to prevent other chronic diseases.
2.An investigation of the effects of curcumin on anxiety and depression in obese individuals: A randomized controlled trial.
Habibollah ESMAILY ; Amirhossein SAHEBKAR ; Mehrdad IRANSHAHI ; Shiva GANJALI ; Akram MOHAMMADI ; Gordon FERNS ; Majid GHAYOUR-MOBARHAN
Chinese journal of integrative medicine 2015;21(5):332-338
OBJECTIVETo investigate the effectiveness of curcumin, a natural polyphenolic compound with antioxidant and anti-inflammatory activities, on the frequency of symptoms of anxiety and depression in obese individuals.
METHODSIn this double blind, cross-over trial, 30 obese subjects were randomized to receive either curcumin (1 g/day) or placebo for a period of 30 days. Following a wash-out interval of 2 weeks, each subject was crossed over to the alternative regimen for a further 30 days. Severity of anxiety and depression was assessed at baseline and at weeks 4, 6 and 10 of the trial using the Beck Anxiety Inventory (BAI) and Beck Depression Inventory (BDI) scales, respectively.
RESULTSMean BAI score was found to be significantly reduced following curcumin therapy (P=0.03). However, curcumin supplementation did not exert any significant impact on BDI scores (P=0.7).
CONCLUSIONCurcumin has a potential anti-anxiety effect in individuals with obesity.
Adult ; Anxiety ; complications ; drug therapy ; Curcumin ; therapeutic use ; Demography ; Depression ; complications ; drug therapy ; Female ; Humans ; Male ; Obesity ; complications ; drug therapy ; Placebos ; Psychiatric Status Rating Scales
3.Effects of iron supplementation twice a week on attention score and haematologic measures in female high school students.
Akram REZAEIAN ; Majid GHAYOUR-MOBARHAN ; Seyed Reza MAZLOUM ; Mehri YAVARI ; Seyed-Ali JAFARI
Singapore medical journal 2014;55(11):587-592
INTRODUCTIONIron deficiency, associated with a decline in cognitive function, is the most common nutritional deficiency globally. The present study aimed to identify the impact of weekly iron supplements on the attention function of female students from a high school in North Khorasan Province, Iran.
METHODSThis was a blind, controlled, clinical trial study, involving 200 female students who were chosen using the stratified randomised sampling method. First, laboratory studies were performed to detect iron consumption limitations. Next, the 200 students were divided randomly and equally into case and control groups. The case group was treated with 50 mg of ferrous sulfate twice a week for 16 weeks. We compared both groups' data on attention, iron status and erythrocyte indices. Questionnaires were used to collect demographic data, while clinical data was collected using complete blood count and Toulouse-Piéron tests. Data was analysed using descriptive statistics, as well as paired and independent t-tests.
RESULTSThe mean attention scores of the case and control groups were 104.8 ± 7.0 and 52.7 ± 9.6, respectively (p < 0.001). The mean haemoglobin levels of the two groups were 12.5 ± 0.9 and 11.2 ± 1.0, respectively (p < 0.001). Compared to the control group, the attention scores and haemoglobin concentrations of the case group were found to be improved by approximately 90% and 10%, respectively.
CONCLUSIONOral iron supplements (50 mg twice a week for 16 weeks) were able to improve the attention span and haematologic indices of female high school students.
Administration, Oral ; Adolescent ; Attention ; physiology ; Blood Cell Count ; Cognition ; physiology ; Dietary Supplements ; Double-Blind Method ; Erythrocyte Indices ; Female ; Ferrous Compounds ; administration & dosage ; Humans ; Surveys and Questionnaires
4.High Levels of Anti-Heat Shock Protein 27 Antibody in Pemphigus Vulgaris.
Mohammad Javad YAZDANPANAH ; Ali Reza TAJI ; Zari JAVIDI ; Fakhrozaman PEZESHKPOOR ; Amir Ali RAHSEPAR ; Shima TAVALLAIE ; Akram MOMENZADEH ; Saber SHOJAIE-NOORI ; Mohsen KHODDAMI ; Sara RAHSEPAR ; Majid GHAYOUR-MOBARHAN ; Gordon Ashley Anthony FERNS
Annals of Dermatology 2013;25(2):266-268