Objective:To explore the risk factors of acute kidney injury (AKI) after robot-assisted radical prostatectomy.Methods:The clinical data of 605 patients who underwent robot-assisted radical prostatectomy in Nanjing Drum Tower Hospital from June 2017 to June 2019 were retrospectively analyzed. The independent risk factors of AKI were analyzed by Logistic regression.Results:Univariate analysis showed that age ( P = 0.001), anemia ( P = 0.036), hypoalbuminemia ( P = 0.001), coronary heart disease ( P = 0.040), hypertension ( P = 0.042), use of ACEI/ARB drugs ( P = 0.025), duration of MAP < 55 mmHg (1 mmHg = 0.133 kPa)( P = 0.000) presented statistical significance( P < 0.05). Multivariate Logistic regression analysis showed that there were significant difference in age ( P = 0.016), hypoalbuminemia ( P = 0.009), duration of MAP < 55 mmHg ( P = 0.003). Conclusions:Age, anemia, hypoalbuminemia, coronary artery disease, hypertension, use of ACEI/ARB drugs, duration of MAP < 55 mmHg are risk factors of postoperative AKI, among which age, hypoalbuminemia, duration of MAP < 55 mmHg are independent risk factors.

Objective:To evaluate the effect of preoperative chemotherapy on the intraoperative hemodynamics and quality of early postoperative recovery in patients undergoing tumor resection.Methods:This was a prospective cohort study. A total of 249 patients undergoing malignant tumor resection in the Affiliated Cancer Hospital of Xinjiang Medical University from January to August 2023 were divided into chemotherapy group (group C, n=104) and non-chemotherapy group (group N, n=145) based on their chemotherapy history. Heat rate and mean arterial pressure were recorded on admission (T 0), 1 min before endotracheal intubation (T 1), immediately after endotracheal intubation (T 2), at skin resection (T 3), 30 min after endotracheal incision (T 4), at the end of surgery (T 5) and 24 h after surgery (T 6), and the Quality of Recovery-15 score was recorded at T 6. The occurrence of hypoxemia, oropharyngeal airway implantation, bucking and aspiration after tracheal extubation was observed. The occurrence of postoperative nausea and vomiting was recorded. Results:Compared with group N, the mean arterial pressure was significantly decreased at T 1 and increased at T 2, 3, the heart rate was increased at T 2-5, the total Quality of Recovery-15 score, postoperative physical comfort score, emotional state score and pain score were decreased at T 6, and the incidence of hypoxemia and postoperative nausea and vomiting after tracheal extubation was increased in group C ( P<0.05). Conclusions:Preoperative chemotherapy can affect the intraoperative hemodynamic stability and the quality of early postoperative recovery is decreased in patients undergoing preoperative tumor resection.