Objective Discuss the surgical options for the chronic pancreatitis on the basis of anatomical morphological changes.Methods A retrospective review of chronic pancreatitis patients in Department of Pancreatic Surgery,West China Hospital,Sichuan University between January 2010 and December 2014 was performed.The data of medical records,image feature,surgical types and records of follow-up were collected.Total 295 patients including 275 male and 20 female aged from 14 to 74 years with median age of 51 years.The clinical symptoms included abdominal pain in 280 cases,jaundice in 3 cases,single hemorrhage in digestive tract,diarrhea or mellitus in 12 cases.The anatomical morphological changes included pancreatic fibrosis and atrophy of the main pancreatic duct lesions in 44 cases (14.9％),inflammatory mass in the pancreatic head in 69 cases (22.4％),sporadic stones with calcification in the pancreatic head in 165 cases(55.9％),hyperplasia mass of pancreatic head and body in 14 cases (4.8％),sporadic stones with calcification in whole branch ducts accompanied with different degree of hyperplasia in whole pancreas in 3 cases (1.0％).The surgical options included longitudinal pancreaticojejunostomy,duodenum-preserving pancreatic head resection,Frey/Frey + distal pancreatectomy,total and subtotal pancreatectomy.All patients were followed-up for 3 to 6 months in the outpatient.A cross-sectional study was carried out by telephone,letters,questionnaire and outpatient from April to June 2016.Results Among 295 patients,267 cases were followed-up for an average time of 40 months(18 to 78 months),28 cases were lost to followed-up(9.5％).Pain remission rate of pancreatic fibrosis and atrophy of the main pancreatic duct lesions patients was 97.0％,of inflammatory mass in the pancreatic head patients was 96.8％,of sporadic stones with calcification in the pancreatic head patients was 96.6％,of hyperplasia mass of pancreatic head and body patients was 12/13,of sporadic stones with calcification in whole branch ducts accompanied with different degree of hyperplasia in whole pancreas patients was 3/3.There were 19 cases(9.6％) with blood glucose rising.Conclusion According to the pathological changes of chronic pancreatitis,the reasonable choice of surgical procedures can be done to maximize the removal of the cause of pain and the preservation of pancreatic tissue.

Objective Discuss the surgical options for the chronic pancreatitis on the basis of anatomical morphological changes.Methods A retrospective review of chronic pancreatitis patients in Department of Pancreatic Surgery,West China Hospital,Sichuan University between January 2010 and December 2014 was performed.The data of medical records,image feature,surgical types and records of follow-up were collected.Total 295 patients including 275 male and 20 female aged from 14 to 74 years with median age of 51 years.The clinical symptoms included abdominal pain in 280 cases,jaundice in 3 cases,single hemorrhage in digestive tract,diarrhea or mellitus in 12 cases.The anatomical morphological changes included pancreatic fibrosis and atrophy of the main pancreatic duct lesions in 44 cases (14.9％),inflammatory mass in the pancreatic head in 69 cases (22.4％),sporadic stones with calcification in the pancreatic head in 165 cases(55.9％),hyperplasia mass of pancreatic head and body in 14 cases (4.8％),sporadic stones with calcification in whole branch ducts accompanied with different degree of hyperplasia in whole pancreas in 3 cases (1.0％).The surgical options included longitudinal pancreaticojejunostomy,duodenum-preserving pancreatic head resection,Frey/Frey + distal pancreatectomy,total and subtotal pancreatectomy.All patients were followed-up for 3 to 6 months in the outpatient.A cross-sectional study was carried out by telephone,letters,questionnaire and outpatient from April to June 2016.Results Among 295 patients,267 cases were followed-up for an average time of 40 months(18 to 78 months),28 cases were lost to followed-up(9.5％).Pain remission rate of pancreatic fibrosis and atrophy of the main pancreatic duct lesions patients was 97.0％,of inflammatory mass in the pancreatic head patients was 96.8％,of sporadic stones with calcification in the pancreatic head patients was 96.6％,of hyperplasia mass of pancreatic head and body patients was 12/13,of sporadic stones with calcification in whole branch ducts accompanied with different degree of hyperplasia in whole pancreas patients was 3/3.There were 19 cases(9.6％) with blood glucose rising.Conclusion According to the pathological changes of chronic pancreatitis,the reasonable choice of surgical procedures can be done to maximize the removal of the cause of pain and the preservation of pancreatic tissue.

OBJECTIVE: To retrospectively analyze the clinical characteristics and prognostic factors of patients with primary cutaneous lymphoma. METHODS: The clinical data of 22 patients with primary cutaneous lymphoma admitted to Xinjiang Hotan District People's Hospital, Heji Hospital affiliated to Changzhi Medical College and the Fifth Medical Center of PLA General Hospital from January 2013 to June 2021 were retrospectively analyzed. RESULTS: The incidence of primary cutaneous T cell and NK/T cell lymphoma was about 91.9/100 000, and the incidence of primary cutaneous B cell lymphoma was about 14.5/100 000. The overall survival (OS) of patients aged ≥65 years was significantly shorter than that of patients younger than 65 years (P <0.05). Patients with elevated β₂-microglobulin (β₂-MG) had shorter OS and progression-free survival (PFS) (both P <0.05). Patients who achieved complete/partial response after initial treatment had longer OS than those with stable or progressive disease (P <0.05). There were significant differences in OS and PFS among patients with different pathological types of primary cutaneous lymphoma that originated from T and NK/T cells, the OS and PFS of patients with mycosis fungoides were longer than those of patients with other pathological types (both P <0.05). In addition, disease stage might also affect the PFS of the patients (P =0.056). CONCLUSION The age, disease stage, β₂-MG level, pathological type and remission state after treatment of the patients were related to the clinical prognosis.
Humans ; Prognosis ; Retrospective Studies ; Remission Induction ; Lymphoma