1.Application value of magnetic compression anastomosis in digestive tract reconstruction.
Xilin DU ; Chao FAN ; Hongke ZHANG ; Jianguo LU
Chinese Journal of Gastrointestinal Surgery 2014;17(5):512-515
Magnetic compression anastomosis can compress tissues together and restore the continuity. Magnetic compression anastomosis mainly experienced three stages: magnetic ring, magnetic ring and column, and smart self-assembling magnets for endoscopy (SAMSEN). Nowadays, the magnetic compression anastomosis has been applied in vascular and different digestive tract surgeries, especially for complex surgery, such as anastomotic stenosis of biliary ducts after liver transplantation or congenital esophageal stenosis. Although only case reports are available at present, the advantages of the magnetic compression anastomosis includes lower cost, simplicity, individualization, good efficacy, safety, and minimally invasiveness. We are building a better technical platform to make magnetic compression anastomosis more advanced and popularized.
Anastomosis, Surgical
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methods
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Digestive System Surgical Procedures
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methods
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Humans
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Magnetics
2.Development of measurement and control technologies for hyperthermia treatments of tumors with AC magnetic field.
Zhong-hua GUO ; Lu-xin TANG ; Jin-tian TANG ; Bin XIE ; Xiao-hui DENG
Chinese Journal of Medical Instrumentation 2006;30(1):39-42
Hyperthermia therapy with AC magnetic field heating magnetic nanoparticles is a new kind of treatment method. The paper reviews the research progresses about AC magnetic heating setups for hyperthermia therapy measurements of magnetic field temperature control, and so on.
Humans
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Hyperthermia, Induced
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methods
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Magnetics
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Nanotechnology
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Neoplasms
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therapy
3.The Development of Anastomat of Digestive Tract Based on the Magnetic Compressive Technique.
Hongke ZHANG ; Yi LV ; Chang LIU ; Liang YU ; Xuemin LIU ; Dinghui DONG ; Feng MA ; Haohua WANG
Chinese Journal of Medical Instrumentation 2015;39(5):331-333
A new anastomat for digestive tract operations, based on the magnetic compressive technique and mechanical transmission mechanism, is composed of a removable head and a reusable body. The head includes two parts: the proximal end can be fixed to the body, and the distal end could be used for performing a purse string suture. The procedure of anastomosis is similar to that of the stapler, and the anastomoses is established using a pair of magnetic rings. The instrument makes magnamosis more simple and feasible, and it would facilitate the clinical application. The body of the anastomat is reusable and the head could be replaced according to the clinical scenarios, these could reduce the medical cost. The magnetic rings would be excreted with the feces, and there is no foreign body response at last.
Anastomosis, Surgical
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instrumentation
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methods
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Gastrointestinal Tract
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surgery
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Humans
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Magnetics
4.A comparative study on dual-magnetic circuit beads and scattering nephelometry coagulometers in coagulational evaluation of blood-contact medical devices.
Tun YUAN ; Jie LIANG ; Jing SAN ; Li-Ping ZHENG ; Wei-Jing ZHU
Chinese Journal of Medical Instrumentation 2008;32(1):54-57
Dual-magnetic circuit beads and scattering nephelometry dual channel semiautomatic coagulometers are used for the coagulational evaluation of the 5 blood contact medical devices which consist of metals and polymers. The partial thromboplastin time(PTT) and prothrombin time(PT) tests are made based on the GB/T 16886.4-2003 standard. The results indicate that the coefficient of variation in the two groups is in the identical order of magnitude. In the PTT tests, they give the similar evaluational results. With the smaller numerical values of the PT tests, the different coagulometers give the high consilience results. So, both of dual-magnetic circuit beads and scattering nephelometry coagulometers are acceptable in the medical devices' coagulational evaluations. But the interpretation and analysis of the results of the small numerical value tests, PT tests for example, should be noticed.
Blood Coagulation Tests
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instrumentation
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methods
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Magnetics
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instrumentation
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Nephelometry and Turbidimetry
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instrumentation
5.An image reconstruction algorithm based on L(P)-norm for magnetic induction tomography.
Yuyan CHEN ; Xu WANG ; Dan YANG ; Yi LU
Journal of Biomedical Engineering 2013;30(1):162-165
Magnetic induction tomography (MIT) image reconstruction is a typical ill-posed problem, and its numerical solution is unstable. A new image reconstruction algorithm based on the L(P)-norm, which solves the ill-posed inverse problem of MIT and improves the quality of reconstructed image, is presented in this paper. The new algorithm not only overcomes the problem of numerical instability of the MIT image reconstruction, but also improves the quality of the reconstructed image and enhances the spatial resolution of the reconstructed image. Simulation results showed that the quality of the reconstructed image obtained using the presented algorithm was better than that using Tikhonov regularization algorithm and that using the variation regularization algorithm, so it could be an effective method for the MIT.
Algorithms
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Image Processing, Computer-Assisted
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methods
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Magnetics
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Models, Theoretical
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Tomography
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methods
6.Experiment and analyse on the effect of magnetic nanoparticles upon relaxation time of proton in molecular recognition by MRI.
Lili HU ; Tao SONG ; Wenhui YANG ; Ming WANG ; Fang ZHANG ; Chunjing TAO
Journal of Biomedical Engineering 2007;24(3):590-614
To research on the effect of three different magnetic nanoparticles upon relaxation time of proton. The detection by magnetic resonance imaging (MRI) indicates that there is the effect of marked difference to right control experiment and to analyze the difference from theory. The result discloses that will be able to perform the experiment of molecular recognition using magnetic nanoparticles later.
Ferric Compounds
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chemistry
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Humans
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Magnetic Resonance Imaging
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instrumentation
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methods
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Magnetic Resonance Spectroscopy
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methods
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Magnetics
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Nanoparticles
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Protons
7.Study of functional magnetic stimulation.
Journal of Biomedical Engineering 2002;19(1):154-157
Functional magnetic stimulation (FMS) is a new technique for stimulation on excitable neuromuscular cell and provides extensive applications with many advantages, such as deep stimulation, less pain, non-invasive approach and easy to operate technique. In this paper, the new reports of FMS are introduced including the principle, stimulator, coils, results of experiments and our research on analgesic effect of FMS.
Analgesia
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methods
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Animals
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Dogs
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Electric Stimulation
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instrumentation
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methods
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Electromagnetic Fields
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Humans
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Magnetics
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therapeutic use
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Rats
8.Magnetic properties and heavy metal contents of automobile emission particulates.
Sheng-gao LU ; Shi-qiang BAI ; Jing-bo CAI ; Chuang XU
Journal of Zhejiang University. Science. B 2005;6(8):731-735
Measurements of the magnetic properties and total contents of Cu, Cd, Pb and Fe in 30 automobile emission particulate samples indicated the presence of magnetic particles in them. The values of frequency dependent susceptibility (chi(fd)) showed the absence of superparamagnetic (SP) grains in the samples. The IRM(20 mT) (isothermal remanent magnetization at 20 mT) being linearly proportional to SIRM (saturation isothermal remanent magnetization) (R(2)=0.901), suggested that ferrimagnetic minerals were responsible for the magnetic properties of automobile emission particulates. The average contents of Cu, Cd, Pb and Fe in automobile emission particulates were 95.83, 22.14, 30.58 and 34727.31 mg/kg, respectively. Significant positive correlations exist between the magnetic parameters and the contents of Pb, Cu and Fe. The magnetic parameters of automobile emission particulates reflecting concentration of magnetic particles increased linearly with increase of Pb and Cu content, showed that the magnetic measurement could be used as a preliminary index for detection of Pb and Cu pollution.
Algorithms
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Environmental Monitoring
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methods
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Feasibility Studies
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Magnetics
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Metals, Heavy
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analysis
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chemistry
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Statistics as Topic
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Vehicle Emissions
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analysis
9.Design and implementation of a new type excitation source and the optimal excitation coil for MIT.
Mingke JIAO ; Mingxin QIN ; Wenwen LIANG ; Hao YANG ; Wenyong WANG ; Xiaoyan HU ; Hua ZHANG ; Ke LI ; Wei ZHOU
Journal of Biomedical Engineering 2009;26(2):234-238
This research work was aimed to improve the performance of magnetic induction tomography (MIT) system by designing a high-performance excitation source and the optimal excitation coil. A new type excitation source with adjustable output was designed, and then the power circuit was simulated by the software ICPA. Focused and solenoid coils were designed in accordance with the design principle of coil, then the optimal excitation coil was proved by measuring the magnetic field distribution and the experimentation of phase detection using neuron cell models. At the stated excitation frequency, the parameters of the excitation source are output power 0.035 W-31.4 W, steady output peak current over 1 A, frequency stability 10(-9), and THD amplitude less than -51dB. When compared with other coils, the focused discal excitation coil is most effective for phase detection with the use of neuron cell models. The excitation source can produce the stated frequency sine wave with higher frequency stability, lower THD and wider adjustable output power. The phase difference between normal cell model and edema cell model was more significant by measurement using focused discal coil.
Brain
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physiology
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Electronics, Medical
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instrumentation
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Equipment Design
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Humans
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Image Processing, Computer-Assisted
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Magnetics
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instrumentation
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Tomography
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methods
10.In vitro gene transfection by magnetic iron oxide nanoparticles and magnetic field increases transfection efficiency.
Juan-juan XIANG ; Xin-min NIE ; Jing-qun TANG ; Yan-jin WANG ; Zheng LI ; Kai GAN ; He HUANG ; Wei XIONG ; Xiao-ling LI ; Gui-yuan LI
Chinese Journal of Oncology 2004;26(2):71-74
OBJECTIVETo evaluate the feasibility of using iron oxide nanoparticles as gene vector and the effect of magnetic field on efficiency of transfection.
METHODSIron oxide nanoparticles were prepared by alkaline precipitation of divalent and trivalent iron chloride. The surface of iron oxide nanoparticles was modified by self-assembled poly-L-lysine to form particle complexes (IONP-PLL). Transfection was determined by delivering reporter gene, PGL2-control encoding luciferase, to different cell lines using IONP-PLL as vector. The effect of magnetic field on efficiency of transfection was determined using Nd-Fe-B permanent magnet.
RESULTSForeign gene could be delivered to various cell lines by IONP-PLL and expressed with high efficiency, but the transfection efficiency and time course varied in the different cell lines studied. Magnetic field could enhance the efficiency of transfection by 5 - 10 fold.
CONCLUSIONIONP-PLL can be used as a novel non-viral gene vector in vitro, which offers a basis for gene delivery in vivo.
Animals ; COS Cells ; Ferric Compounds ; administration & dosage ; Genetic Vectors ; Magnetics ; Polylysine ; administration & dosage ; Transfection ; methods