1.Efficacy of guava 5% cream vs. clotrimazole 1% cream in the treatment of Tinea corporis of patients seen at the Family Medicine Department of Quezon City General Hospital
Ma. Victoria Valenzuela-Gochingco
The Filipino Family Physician 2020;58(1):37-41
Objective:
To determine the efficacy of Guava 5% cream compared to Clotrimazole 1% cream in the treatment of Tinea corporis of patients seen at Family Medicine Department of Quezon City General Hospital
Design:
Randomized therapeutic clinical trial
Setting:
Department of Family and Community Medicine Out Patient Department of Quezon City General Hospital
Study Subjects:
Patients, male or female, 19 years old and above who consulted at Family and Community Medicine Department of Quezon City General Hospital
Method:
The study was done from August- September 2019. Fifty subjects were randomly assigned to either Group A (25) or Group B (25) using systematic sampling method. Patients in Group A were instructed to apply on affected area Clotrimazole 1% Cream twice a day for 2 weeks, while patients on Group B applied Guava 5% cream twice a day for 2 weeks. Patients were instructed follow up on Week 1 for improvement, Week 2 for evaluating outcome of treatment and Week 4 to check for recurrences
Results:
Total severity scores of both Groups A and B at Week 1, Week 2 and Week 4 were similar with p-values of 0.014, 0.480 and 0.386 respectively. Both groups were comparable as to the treatment outcome for Tinea corporis. Guava 5% cream is shown to be cost-effective considering the equally-effective treatment outcome and the lower average treatment cost
Conclusion
This study has shown that Guava 5% cream is equally effective as, and cheaper than Clotrimazole 1% cream, thus considered to be a cost-effective treatment for Tinea corporis.
Tinea
;
Psidium
;
Clotrimazole