1.Prevalence of dyslipidemia among residents aged 35 years and above in Changzhou City
MI Xiaomeng ; XIONG Suting ; XU Wenguo ; XU Wenchao
Journal of Preventive Medicine 2025;37(2):173-177
Objective:
To investigate the prevalence and influencing factors of dyslipidemia among residents in Changzhou City, Jiangsu Province, so as to provide insights into improving prevention and control strategies of dyslipidemia.
Methods:
Permanent residents aged 35 to 75 years were recruited based on the Early Screening and Comprehensive Intervention Project for High-risk Populations of Cardiovascular Disease in Changzhou City from 2016 to 2023. Demographic information, body mass index (BMI), total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C) were investigated through questionnaire surveys, physical examinations and laboratory tests, and the prevalence of dyslipidemia were analyzed. Factors affecting dyslipidemia were identified using a multivariable logistic regression model.
Results:
A total of 22 447 residents were surveyed, including 9 142 males (40.73%) and 13 305 females (59.27%), and had a median age of 57.00 (interquartile range, 18.00) years. There were 7 535 cases of dyslipidemia, with a prevalence rate of 33.57%. The prevalence rates of low HDL-C, high TG, high TC, and high LDL-C were 22.27%, 15.89%, 4.06% and 2.27%, respectively. Multivariable logistic regression analysis showed that the residents who were male (OR=1.780, 95%CI: 1.645-1.924), had more than 50 000 yuan of annual household income (OR=1.215, 95%CI: 1.142-1.293), had higher educational level (junior high school/senior high school/technical secondary school, OR=1.138, 95%CI: 1.047-1.237; junior college and above, OR=1.232, 95%CI: 1.095-1.386), smoked frequently (OR=1.504, 95%CI: 1.369-1.653), were overweight (OR=1.763, 95%CI: 1.650-1.885) or obese (OR=2.351, 95%CI: 2.149-2.572), had hypertension (OR=1.478, 95%CI: 1.384-1.579) and diabetes (OR=1.706, 95%CI: 1.586-1.835) had a higher risk of dyslipidemia; while the residents who consumed alcohol at 4 times per week and more (OR=0.619, 95%CI: 0.557-0.688) had a lower risk of dyslipidemia.
Conclusions
The main types of dyslipidemia are low HDL-C and high TG among residents aged 35 years and above in Changzhou City. The prevalence of dyslipidemia is mainly associated with gender, annual household income, educational level, smoking, alcohol consumption, BMI, hypertension and diabetes.
2.Sepsis after liver transplantation:a report of one case and interpretation of International Guidelines for Management of Severe Sepsis and Septic Shock
Huimin YI ; Xuxia WEI ; Lijuan LI ; Yuling AN ; Haijin LYU ; Xiaomeng YI ; Jianrong LIU ; Liang XIONG ; Mi ZHOU ; Pinglan LU ; Yu GUO
Organ Transplantation 2015;(6):378-381
Objective To summarize the treatment experience of sepsis after liver transplantation.Methods The clinical features and treatment methods of 1 patient developing sepsis after liver transplantation, who was admitted and treated in the Surgical Intensive Care Unit of the Third Affiliated Hospital of Sun Yat-sen University in September 201 4,were retrospectively studied.The interpretation of International Guidelines for Management of Severe Sepsis and Septic Shock (SSC Guidelines)and relevant literature were reviewed.Results One male patient at the age of 50 years old developed high fever and decrease of blood pressure at 1 d after liver transplantation,and was diagnosed as septic shock.The symptoms were relieved after the appropriate treatment like goal-directed fluid resuscitation,anti-infection and blood purification,etc.And the patient was discharged in stable conditions.Conclusions It is easy to develop infection after liver transplantation and the fatality rate of sepsis caused by infection is high.Once the sepsis occurs,clinicians must perform early goal-directed therapy and bundle therapy according to the SSC Guidelines positively,and select the appropriate drugs according to the pathogen culture results in order to reduce the fatality rate.
3.A cone-beam CT study on morphology and position of condylar processes in skeletal Class Ⅲ adult patients with mandibular deviation
Jun LIU ; Meiqing YU ; Fusheng DONG ; Mi WANG ; Xiaomeng WEN ; Wensheng MA
Chinese Journal of Stomatology 2014;49(7):403-407
Objective To evaluate the morphology and position of condylar processes in skeletal Class Ⅲ adult patients with mandibular deviation.Methods Twenty skeletal Class Ⅲ adult patients with mandibular deviation were selected as the deviated group and twenty adults with normal occlusion were selected as the control group.Cone-beam CT(CBCT) scans of their temporomandibular joints were taken.The original data were reconstructed and rebuilt.A series of measurements of the condylar morphology and location were performed.The collected data were analyzed using paired t-test.Results In the deviated group,the deviated sides were smaller than the contralateral sides in the perpendicular height,volume,maximum area of axial plane and the height of condylar head.The contralateral condyle was positioned more posteriorly and laterally [(0.35 ± 0.10) and (0.58 ± 0.18) mm] than the deviated condyle (P<0.05).Conclusions Adult skeletal Class Ⅲ patients with mandibular deviation hadsome extent of condyle asymmetry in both morphology and location.
4.Drug sensitivity analysis ofAcinetobacter baumannii in organ transplantation patients
Lijuan LI ; Binsheng FU ; Mi ZHOU ; Pinglan LU ; Xuxia WEI ; Jianrong LIU ; Xiaomeng YI ; Huimin YI
Chinese Journal of Hepatic Surgery(Electronic Edition) 2015;(6):360-362
ObjectiveTo investigate the drug sensitivity ofAcinetobacter baumannii in organ transplantation patients.MethodsClinical data of 66 patients detected withAcinetobacter baumannii in the Third Affiliated Hospital of Sun Yat-sen University between June 2012 and June 2015 were retrospectively studied. The informed consents of all patients were obtained and the local ethical committee approval had been received. Among the 66 patients, 55 were males and 11 were females with the average age of (47±12) years old. Among the 66 patients, 11 cases were before liver transplantation, 52 were after liver transplantation, 1 was after kidney transplantation and 2 were in liver transplantation state. Sputum, urine, blood, wound secretion and drainage liquid of the patients were collected for bacterial culture and drug sensitivity test.ResultsA total of 73 strains ofAcinetobacter baumannii cultured from the specimens of 66 patients and the drug resistance rate to 13 antibiotics was respectively 78% to piperacillin sodium, 75% to cefotaxime sodium, 74% to ceftazidime, 73% to ceftriaxone sodium, 74% to cefepime, 73% to meropenem/imipenem-cilastatin sodium, 75% to ticarcillin sodium-clavulanate potassium, 73% to ciprolfoxacin, 71% to levolfoxacin, 73% to tobramycin, 73% to gentamycin, 73% to amikacin and 69% to trimethoprim/sulfadiazine. The resistance rate ofAcinetobacter baumannii cultured between 2014 and 2015 to the aforementioned antibiotics was higher than that cultured between 2012 and 2013. The resistance rate to carbapenems was 17% in 2012, 33% in 2013, 86% in 2014 and 92% in 2015.ConclusionThe infection incidence of multi-drug resistantAcinetobacter baumannii in organ transplantation patients trends to increase year by year, which shall be paid attention to during the treatment.