Objective to compare the calculated effective radiation dose variations in cardiac interventional procedures of coronary angiography(CAG)and percutaneous transluminal coronary angioplasty (PCI)by using the different tissue weighting factors recommended by ICRP Publication 60 with that recommended by ICRP Publication 103.Methods Measurements of organ doses were carried out with an anthropomorphic phantom equipped with thermoluminecent dosimetry.The effective radiation doses were separately calculated using the tissue weighting factors provided by ICRP 60 and provided by ICRP 103,and the results obtained from ICRP 60 were compared with that obtained from ICRP 103.Conversion factors of effective radiation dose to dose area product(DAP)were also calculated according to different publication. Results The variations in the effective dose were 6.88%for CAG and 8.46%for PCI.The effective dose variations in CAG and PCI were 7.25%and 8.76%for female and were 6.51%and 8.17%for male, respectively.The effective conversion factors of DAP were 0.10～0.11 and 0.13～0.14 for CAG and PCI, respectively,according to ICRP 60 and 103.Conclusion The variation of conversion factors of effective dose indicates that in making estimation of effective radiation dose by using the widely accepted conversion factors,the adjustment of organ weighting factors recommended by ICRP 103 should be considered.

Objective to compare the calculated effective radiation dose variations in cardiac interventional procedures of coronary angiography (CAG) and percutaneous transluminal coronary angioplasty (PCI) by using the different tissue weighting factors recommended by ICRP Publication 60 with that recommended by ICRP Publication 103. Methods Measurements of organ doses were carried out with an anthropomorphic phantom equipped with thermoluminecent dosimetry. The effective radiation doses were separately calculated using the tissue weighting factors provided by ICRP 60 and provided by ICRP 103, and the results obtained from ICRP 60 were compared with that obtained from ICRP 103. Conversion factors of effective, radiation dose to dose area product (DAP) were also calculated according to different publication.Results The variations in the effective dose were 6.88% for CAG and 8.46% for PCI. The effective dose variations in CAG and PCI were. 7.25% and 8.76% for female and were 6.51% and 8.17% for male,respectively. The effective conversion factors of DAP were. 0.10 ～ 0.11 and 0.13 ～ 0.14 for CAG and PCI,respectively, according to ICRP 60 and 103. Conclusion The variation of conversion factors of effective dose indicates that in making estimation of effective radiation dose. by using the widely accepted conversion factors, the adjustment of organ weighting factors recommended by ICRP 103 should be considered.

Objective To estimate the effective dose during 64-slice CT examination on head,chest and abdomen and determine the conversion coefficient of effective dose and dose length product(DLP).Methods The plain CT scan wag performed in 48 cases on head,50 cases on chest and 45 cages on abdomen using GE Lightspeed 64-slice spiral CT.1The Kv,Ma,scan time,CTDIvol,and DLP were recorded in each examination.Effective dose on patients Was estimated using the SR 250 software.Results The effective dose on head,chest and abdomen was(3.1±0.1),(6.9±0.1)and(8.0±0.1)mSv,and the conversion Coeffieient was 0.0025,0.0191 and 0.0166 mSv·mGy-1·cm-1 respectively.Conclusion CTDIvol、DLP and effective dose were recommended for patient dose control during CT examination.The conversion factor of effective dose and DLP were recommended for radiation risk evaluation during different X-ray examinations.

Objective To assess the dose and image quality using a C-arm CT (DynaCT) system and compare the difference of image quality and radiation dose between DynaCT and Multi slice CT (MSCT). Methods Effective doses were measured from an anthropomorphic phantom with embedded thermoluminescence dosimeters (TLDs).For DynaCT,automatic exposure control (AEC) and high-quality (20 s rotation time) scans were used. For MSCT,scanning protocols for head were examined with conventional exposure conditions. Catphan phantom(Phantom Lab,USA) was used to evaluate the image quality for DynaCT and MSCT. Results For DynaCT,the effective doses from head scanning were 1.10 mSv; for MSCT,the effective doses from head scanning were 2.07 mSv,and there was a significant difference of organ dose between DynaCT and MSCT(P

Objective To investigate the influence of organ dose and effective dose on patients for different Z value during head,chest and abdomen CT scan. Methods With equispaced displacement on axis Z,organ dose and effective dose was estimated by using SR250 software with commonly used CT exposure parameters. Results Effective dose changed gradually for different Z value,some organ dose was sensitive to the Z location. Conclusion It is necessary to avoid X-ray sensitive organ in CT examination to minimize radiation risk.

OBJECTIVETo observe the effect of the postpone in skeletal muscle aging process of D-galactose rats by weight training and soy polypeptide supplement in 6 weeks, and discuss the initial mechanism.

METHODSixty male SD rats (three month old)were randomly assigned: 6 week control (C6,) and 6 week model (M6) 6 for each group, 12 week model (M12), big load (B12), small load (S12), peptide (P12), peptide + big load (PB12) and peptide + small load group (PS12) 8 for each group, eight fourteen month rats were taken in the natural aging group. The rats were killed by the end of 6th week and 12th week, tested the indicators.

RESULTCompare with group C6, the indicators in group M6 showed aging in different levels; Compare with group M12, weight training or soy polypeptide supplement in all intervention groups could increase the content of skeletal muscle superoxide dismutase (SOD), SOD/MDA, the serum growth hormone(GH), insulin-like growth factor-1 (IGF-I)and skeletal muscle IGF-I mRNA, decreased the malondialdehyde (MDA) content of skeletal muscle, and they had notable interaction.

CONCLUSIONRat skeletal muscle aging model can be copied successfully by D-galactose hypodermic, and go on with 6-week weight training or soy polypeptide supplement, they can postpone the skeletal muscle aging process of D-galactose rats, and the two interference way united can have more obvious effect. Its preliminary mechanism may be related to the reduction of skeletal muscle oxidative stress and lipid peroxidation, the correction of hormones and related factors metabolic disorders, the elevation of skeletal muscle IGF-I mRNA expression and so on.

Aging ; physiology ; Animals ; Galactose ; Growth Hormone ; blood ; Insulin-Like Growth Factor I ; metabolism ; Male ; Malondialdehyde ; metabolism ; Muscle, Skeletal ; drug effects ; physiology ; Physical Conditioning, Animal ; physiology ; Rats ; Rats, Sprague-Dawley ; Soybean Proteins ; pharmacology ; Soybeans ; chemistry ; Superoxide Dismutase ; metabolism

By integrating data of sci-tech novelty retrieaval and internet data,the paper makes a precise analysis of the potential demands,interest,interest,tendency,preferences and habits of users of novelty retrieval.From the perspective of big data technology,it analyzes the feasibility of designing targeted and deep-level services for mass user data,puts forward the framework and method of conducting deep-level and precise service recommendation based on users of sci-tech novelty retrieval,and studies the opportunity to provide these users with deep-level and precise services.

Objective To collect information of patient doses of interventional radiology in Beijing Xuanwu Hospital,and investigate correlation between the peak skin dose(PSD) and dose-area product(DAP).Methods Radiation doses from 135 patients have been studied including 84 coronary angiographies(CAG) and 51 percutaneous transluminal coronary angioplasties(PCI).Dose-area product(DAP) values,cumulative dose(CD) at interventional reference points,fluoroscopy times,total number of cine frames were collected for each patient.Skin dose measurements were made with thermoluminescent dosimeters(TLD) placed as a 10 ? 9 arrays of TLDs on the body.The grid of TLDs arrays was 5 ? 4 cm.Results Mean values for dose-area product were 2690.84 ?Gym2 for CAG and 7946.91 ?Gym2 for PCI.Mean values for CD were 431.6 mGy cm2 for CAG and 1395.3 mGy for PCI.Mean fluoroscopy times were 2.9 min for CAG and 10.9 min for PCI and mean number of frames were 544 and 945 for CAG and PCI,respectively.PSD values ranged from 26.18 to 120.37 mGy for CAG and 38.91 to 184.79 mGy for PCI.The relationship between DAP and PSD was r = 0.52 for CAG and r = 0.54 for PCI.The correlation of PSD with CD was r = 0.45 for CAG and r = 0.53 for PCI.Conclusion Comparison shows that patients DAP,CD and fluoroscopy time values were comparable with other publications.Skin dose values of investigated patients are below the threshold dose for radiation skin injury(2 Gy).There is no good relationship between DAP and PSD.So calculation of individual maximum skin dose based on DAP data is not reliable and needs to find a new reference value for skin dose.(J Intervent Radiol,2007,16:222-225)

Objective To investigate the karyotype of Candida albicans DNA by pulsed field gel electrophoresis (PFGE), and evaluate the significance of the karyotype used as a method for molecular epidemiology controlling. Methods 14 isolates of C. albicans from various clinical samples were evaluated for molecular relatedness by PFGE. Isolates were identified by MircroScanWalkAway 96 RY-ID. Results The karyotype analysis revealed a total of 9 different genotypes among 14 isolates of C. albicans from 11 patients. Among the isolates, 4 were isolated from difference parts of a patient and had same karyotype, implying that they were from the same isolate and differed to different sub-clones. In another 10 isolates from different patients, 3 had same karyotype, and the karyotypes of the remainder 7 isolates were different. Conclusion PFGE may well reveal the autoploidy and polymorphism of the isolates of C. albicans with different origin, thus may be used as an effective method for molecular epidemiological study.