1.Effect of exercise at intensities around ventilatory threshold on plasma protein-bound sulfhydryl groups.
MAKOTO SAITO ; TAKAYO INAYAMA ; SEIJI MAEDA ; MITSUO MATSUDA
Japanese Journal of Physical Fitness and Sports Medicine 1997;46(4):365-373
Although it has been established that exercise is useful for health promotion, physical exercise may induce oxidative stress in humans. Our previous study showed that the concentration of plasma protein-bound sulfhydryl groups (p-SHs) was significantly decreased after strenuous exercise, i. e. full-marathon running and participation in an athletic training camp. Reactive oxygen species may cause oxidation of plasma proteins in vitro. To study whether moderate exercise for health promotion, e. g. jogging or walking, induces oxidative stress in human circulating blood, the authors examined the change in plasma p-SHs concentration following ergometric exercise at moderate intensity and of relatively short duration {Exercise 1: 80% ventilatory threshold (VT), 100% VT, and 110% VT; 30 min, Exercise 2 : 90% VT; 120 min} in 8 (23-28 yr; Exercise 1) and 6 males (23-28 yr; Exercise 2) respectively. The plasma p-SHs concentration did not changed significantly after Exercise 1 or 2. The data indicated that the exercise did not cause significant modification of plasma proteins, suggesting that it did not induce significant oxidative stress in the circulating blood.
2.The immediate effects of various treatment styles
Masamichi NAKAMURA ; Mayumi YAKAME ; Hideki SAITO ; Makoto MURAI
Journal of the Japan Society of Acupuncture and Moxibustion 2012;62(2):140-147
[Objective]In clinical practice, it is important that patients experience symptomatic improvement or at least gain a certain level of satisfaction early on during a series of treatments. Most patients decide whether or not to return to the clinic based on these factors. At our school, students are trained in protocols from three different treatment styles:modern acupuncture, meridian acupuncture (based on classic acupuncture) and traditional Chinese medicine. In this study, we investigated the characteristics of each style, such as the presence of immediate effects and the types of sensations perceived by patients.
[Methods]Questionnaires were given before and after treatment to 177 patients who came to the clinic associated with our teacher training course for acupuncture, moxibustion and massage. We received valid responses from 169 patients. The practitioners surveyed were second-year students who had treated the surveyed patients 1.2 times on average prior to answering the questionnaire. Before treatment, patients were asked about their main complaints and symptoms, and afterward about changes in their symptoms, satisfaction level and other sensations. The resulting data was subjected to statistical analysis.
[Results]The style chosen by most practitioners was modern acupuncture, followed by meridian acupuncture, and then traditional Chinese acupuncture. Most lower back, leg and joint pain was treated with modern acupuncture protocols, while internal disorders were more often treated with meridian acupuncture or traditional Chinese acupuncture. All three styles were able to alleviate symptoms and achieve patient satisfaction with no statisticallysignificant differences among the three groups.
[Discussion]The results demonstrated that training practitioners in these three styles for one year helped them achieve positive and immediate effects. While there are many different styles of acupuncture, in actual clinical practice, the style is less important than how much a patient feels the effect of the treatment.
[Conclusion]All three styles, modern acupuncture, meridian acupuncture and traditional Chinese acupuncture, were able to alleviate symptoms and achieve patient satisfaction with no statistically significant differences among them.
3.Changes in the recommended age for rubella-containing vaccine and rubella seroprevalence among pregnant women
Yasutaka Kuniyoshi ; Azusa Kamura ; Sumie Yasuda ; Makoto Tashiro ; Miki Saito ; Rikako Hashimoto
An Official Journal of the Japan Primary Care Association 2014;37(2):99-103
Objectives : To investigate the prevalence of rubella HI antibody among pregnant women in relation to changes in the recommended age for rubella-containing vaccination.
Methods : A total of 659 primiparous women were included in this study. All subjects were ≥20 years old at the time of delivery in our hospital during the 5-year period from January 2008 to December 2012. Rubella HI antibody titers were measured. Subjects were divided into four groups according to their date of birth and retrospectively analyzed : i) single-dose mass vaccination in junior high school generation ; ii) “interim measures generation” ; iii) single-dose vaccination in infancy generation ; and iv) infancy plus catch-up MR two-dose vaccination generation. HI antibody titers ≤1 : 16 was defined as a low antibody titer.
Results : The percentage of cases with low antibody titers in the total study population was 20.2%. The percentages of cases with low antibody titers in each group were : i) 20.4%, ii) 18.2%, iii) 30.6%, and iv) 31.6%.
Conclusion : The percentage of low antibody titers among all cases was comparable to other reports. The results suggested that rubella seroprevalence was low among those in the generation including and subsequent to the single-dose vaccination in infancy generation.
4.PERSONAL SPACE PERCEPTION IN HUMAN ELBOW JOINT
JUNKO MIYAZAKI ; HIROSHI KURATA ; YOSHINORI OGAWA ; YOSHIHIRO SAITO ; ATSUSHI TOKIOKA ; KUNIHIKO HARADA ; SOTOYUKI USUI ; MAKOTO MASUDA
Japanese Journal of Physical Fitness and Sports Medicine 1982;31(4):242-250
In order to examine the personal space perception, measurements were conducted on both elbows in 14 men and 46 women. Each subject, with his (or her) eyes closed and with his upper arm fixed horizontally, was instructed to stop the vertical and horizontal swing motion of his lower arm at the point he considered to be the middle of the range of possible motion on the front and side of plane at his shoulder, and this was repeated ten times. In various conditions, similar measurements were also done to study factors affecting the personal space perception in 14 men.
Mean values of bisected angles in percentage against range of motion were deviated from the middle points in the direction of the elbow extension, although there were large differences between the individuals. The deviation was smallest in the vertical. side of plane, and was larger in the horizontal plane than that in the vertical plane. The deviation was not so much affected by the various conditions.
It was suggested that the gain of the personal space perception is higher in the elbow extension than in the elbow flexion and its difference is larger in the horizontal plane than in vertical plane of the human elbow joint.
5.Learning Strategies of Continuing Medical Education for General Practitioners.
Nobuya HASHIMOTO ; Hiroshi KIKUCHI ; Makoto AOKI ; Masahiko HATAO ; Tomonobu KAWANO ; Kiichiro KOIKE ; Masaji MAEZAWA ; Hiroki NAKATANI ; Toshiro OHMURA ; Haruhiko SAITO
Medical Education 1997;28(1):5-8
Continuing medical education for the general practitioners has been activery performed. The former committee for continuing medical education of the Japan Society for Medical Education reported the objectives of continuing medical education for general practitioners. The present committee proposed learning strategies for continuing medical education for general practitioners in accordance with specific behavioral objectives of the curriculum.
It was postulated that appropriate learning strategies are necessary for physicians to provide holistic medical care in their communities, in addition to improving their medical knowledge and skills.
Learning strategies in the curriculum were also coordinated with the continuing medical education system of the Japan Medical Association.
6.On the Result of a Questionaire Regarding Continuing Medical Education of the Hospital Physicians.
Nobuya HASHIMOTO ; Hiroshi KIKUCHI ; Makoto AOKI ; Masahiko HATAO ; Tomonobu KAWANO ; Kiichiro KOIKE ; Masaji MAEZAWA ; Hiroki NAKATANI ; Toshiro OHMURA ; Haruhiko SAITO
Medical Education 1997;28(2):67-76
The aim of this study is to clarify the definition and recognition on continuing medical education for administrators (or leaders for residents) of 80 university hospitals and 266 clinical training hospitals as designated by the Ministry of Health and Welfare, using the questionaire consited of 5 main questions, as following:
1) On the curriculum (program) of continuing medical education in their hospitals.
2) On the continuing medical education system of Japan Medical Association.
3) On the continuing medical education activity of the specified academic societies.
4) On guide of continuing medical education for the residents.
5) On definition of continuing medical education.
Answers to a questionaire were returned from 227 institutions (65.6%)
Analyzing the results, present situation of program curricula for continuing medical education in hospitals, participation to continuing medical education system of Japan Medical Association and Academic Societies, and consideration on continuing medical education as a hospital leader were comprehensible.
7.A Report of Consideration for Physician's Recognition Award (PRA) in American Medical Association.
Nobuya HASHIMOTO ; Haruhiko SAITO ; Makoto AOKI ; Masahiko HATAO ; Tomonobu KAWANO ; Hideya SAKURAI ; Tadashi MATSUMURA ; Osamu NISHIZAKI ; Toshiro OHMURA ; Shoichi SUZUKI
Medical Education 2000;31(3):153-157
The committee of continuing medical education in Japan Society for Medical Education discussed on PRA of American Medical Association [AMA]. We have first analyzed the brochure of PRA for the members of AMA, and then prepared the questionnaire for AMA. We were able to obtained the answers to the questionnaire which were sent to AMA through courtesy of Japanese Medical Association (JMA). It was realized that AMA emphasizes an importance of PRA for medical practice to the patients; nevertheless acquisition rate of PRA is actually low, and so AMA proceeds with efforts towards completion of PRA.
8.EPIDEMIOLOGICAL STUDY OF INFLUENZA VIRUS INFECTIONS IN YANGON, MYANMAR
GO HASEGAWA ; YADANAR KYAW ; HLA MYAT NEW ; LI DANJUAN ; REIKO SAITO ; HIROSHI SUZUKI ; YUSUKE EBE ; TIN MAUNG CHO ; MAKOTO NAITO
Tropical Medicine and Health 2006;34(1):3-6
Although influenza is a highly contagious acute respiratory illness of global importance, little is known about the disease in tropical countries. An influenza survey was conducted in three sentinel sites in Yangon, Myanmar from September 2003 to December 2004. Throat or nasal swabs were collected from 616 patients with influenza-like symptoms and tested using rapid diagnostic test kits and virus isolation. Influenza B virus was detected in 6 patients from September to October, 2003. Influenza A viruses were detected in 133 patients from June to September, 2004, and the 51 influenza A viruses isolated from 72 specimens were all A⁄H3N2. Influenza virus infections occurred mainly in the rainy season in Yangon, Myanmar, but continuous ongoing influenza surveillance is needed.
9.Tokirikuoto (Dang-Gui-Liu-Huang-Tang) :How it was formulated and its clinical indications seen in Chinese medical classics
Oto MIURA ; Yoshinari KON ; Hidetoshi ITAKURA ; Koichiro TANAKA ; Mikum UEMATSU ; Kazuhiko NARA ; Makoto HASHIGUCHI ; Kazuhisa YOSHIDA ; Kazuyoshi KUWANA ; Sinpei TSUKADA ; Takashi TSUCHIYA ; Atushi FUKUSHIMA ; Takaaki KOSUGE ; Teruo SAITO
Kampo Medicine 2010;61(5):740-745
Dang Gui Liu Huang Tang (in the Lan Shi Mi Cang written by Li Dong-yuan) is a common medicine for treating night sweats. We describe its historical development and therapeutic uses. The use of Huan qi (Radix Astragali sen Hedysari) is based on the Han-Sui dynasty medical principle that night sweats are mainly caused by Deficiency of Yang. Herbs to enrich the lood and Yin, Dang gui (Radix Angelicae Sinesis), Seng di huang (Radix Remannia), Shu di huang Radix Rehmannia preparata) were later added because Son dynasty physicians mentioned that Yin deficiency caused night sweats. The addition of heat-reducing herbs, such as Huang lian (Rhizoma Coptidis), was based on the Song dynasty theory that night sweats are caused by pathologic heat in the body, which forces body fluid out of the skin. In the same period, the herbal medicine called Da Jin Hua Wan created by Liu Wansu, and this greatly influenced the principles for treating night sweats. The clearest explanation can be found in the medical treaties Huang Di Nei Jing Su Wen, and Xuan Ming Lun. This medical combination was based on medical theories from a number of historical periods, which may explain its effectiveness. Dang Gui Liu Huang Tang is not effective against types of weak heat (Dan xin xin fa), severe vital Qi Deficiency (Zhang shi yang), or serious deficiency of Yin (Yi xue xin wu). It sometimes hurts Pi and Wei (digestive system). It is useful in the treatment of spontaneous perspiration (Yi xue zheng zhuang, Jin xue quan shu). In summary, this medicine is most effective when the seriousness of heat and Yin deficiency are almost equal and a slight Qi Deficiency exists, or in cases of spontaneous perspiration.
10.The Historical Development of Theories on Night Sweat Pathophysiology
Oto MIURA ; Takanori MATSUOKA ; Yoshinari KONO ; Hidetoshi ITAKURA ; Koichiro TANAKA ; Mikumo UEMATSU ; Kazuhiko NARA ; Keiko SERIZAWA ; Asuka NAKAYAMA ; Makoto HASHIGUCHI ; Atsushi FUKUSHIMA ; Takaaki KOSUGE ; Teruo SAITO
Kampo Medicine 2012;63(1):1-14
Until the Sui Dynasty in China, night sweat and spontaneous perspiration had been thought to be caused by same pathophysiology, that is, lowered superficial resistance by deficiency of Qi.In the Tang Dynasty, these were considered to have different pathophysiologies and a new principle indicated that pathogenic heat caused night sweat.In the Song and Jing Dynasties, deficiency of blood and pathogenic heat by deficiency of Yin was also considered to cause night sweat.In the Jing Dynasty, exogenous pathogens, such as Cold were considered to cause night sweat, which indicated the principle that not only the deficiency syndrome but also the excess syndrome caused night sweat.In the beginning of the Yuan and Ming Dynasties, it was concluded that the deficiency of Yin caused night sweat and the deficiency of Yang caused spontaneous perspiration.In the middle of the Ming Dynasty, another new theory indicated that deficiency of Yang also possibly caused night sweat; therefore we should diagnose abnormal sweat depending on the pathophysiology in each case.In the Qing Dynasty, new theories were established stating that not only exogenous pathogens but also Damp-heat, undigested food and stagnation of blood, all of which are included in excess syndrome, cause night sweat, and that based on which part of the body sweats occurred we might understand pathophysiology of night sweat. The night sweat by Warm-heat, which is different from the one by Wind-cold, was considered to be caused with deficiency of Yin.Thus we conclude that the theories of night sweat developed over time, based on Chinese medical classics.