Behcet Syndrome ; Child ; Humans ; Intestinal Diseases ; Male

Objective To explore the correlation between metabolic syndrome (MS)and benign prostatic hyperplasia (BPH) and the drug treatment of BPH.Methods 300 cases of BPH patients treated between May 2011 to June 2012 in our hospital and Tong-Hai County hospitals of traditional Chinese medicine were included.The patients were divided into observing group (n=100) and control group (n=200).The observing group was treated with 5-alpha reductase inhibitors (finasteride).100 patients in control group-1 were treated with alpha-1 receptor blockers (terazosin).100 patients in control group-2 were treated with finasteride and terazosin.The changes of symptom scores,maximum urinary flow rate and prostate volume at month 3,month 6 and at end of a year after the treatment were compared among all groups.Results In 300 cases of BPH patients,there are 256 cases (85.3％) of MS+BPH,and 44 cases (14.7％) of simple BPH,with no statistically significant difference between the two groups in age and total cholesterol level (both P＞0.05).Among 256 cases of MS+ BPH,127 cases (49.6％) had diabetes,174cases (68.0％) had hypertension,85 cases (33.2 ％) had hypercholesterolemia or high triglyceride.The body mass index,blood pressure,fasting plasma glucose,IPSS gland volume were significantly higher (P＜0.05),and the maximum urinary flow rate was significantly lower in MS+BPH group than in the pure BPH group (P＜0.05).Prostate volume was positively correlated with age,body mass index,systolic blood pressure,fasting plasma glucose.IPSS score were positively correlated with age,body mass index,fasting blood glucose,total cholesterol.Maximum urinary flow rate were negatively correlated with age,fasting glucose,total cholesterol.At month 3 after treatment,the symptom score,maximum urinary flow rate were better in both of control group 1 and 2 than in the observation group (both P＜0.05).At 6 months after treatment,there was no statistically significant difference between the two groups in the symptom score,maximum urinary flow rate (both P＞0.05),while prostate volume was smaller in the observation group than in controls group 1 (P＜0.05).After a year of treatment,there were statistically significant differences in above indicators between the observe group and control group-1 (all P＜0.05),and had no statistically significant difference between the observe group and control group 2(all P＞0.05).Conclusions Most patients with BPH are suffering from MS at the same time.Body mass index,blood pressure,blood sugar,prostate volume,IPSS are higher in MS+BPH patients than in patients only with BPH.MS may affect the incidence and prognosis of BPH.Finasteride combined with terazosin can be used within 6 months,and finasteride can be used alone after 6 months of the drug therapy.

Objective To observe the effect of Ganshu Granule on different models of fatty liver in rats. Methods Rats with acute fatty liver induced by alcohol and carbon tetrachloride, rats with chronic fatty liver induced by alcohol and high-fat diet, and rats with acute fatty liver induced by ethionine were used, and the effects of different doses of Ganshu Granule on serum lipid metabolism, intrahepatic lipid metabolism and histopathological changes in liver were observed. Results In fatty liver rats induced by alcohol and carbon tetrachloride, Ganshu Granule could reduce the level of total cholesterol (TC), triglycerides (TG), aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (ALP) in serum and could decrease total fat and glycogen(Gn) in liver obviously. In fatty liver rats induced by alcohol and high-fat diet, Ganshu Granule could significantly decrease the level of TC, TG, ALP, LDL and ALT in serum and could reduce the content of total fat, TG and Gn in liver obviously. In fatty liver rats induced by ethionine, Ganshu Granule could decrease the level of TC, TG and ALT in serum, raise the level of HDL in serum and could decrease the content of total fat, TG and Gn in liver obviously. The histopathologic results showed the degree of hepatic steatosis and hepatocellular necrosis were lessened in all of the treated groups. Conclusion Ganshu Granule is effective in preventing and treating fatty liver.

Objective To evaluate the effect of controlled hypotension with nitroglycerin and esmolol in the operation of endoscopic nasal surgery.Methods 60 patients undergoing selective endoscopic nasal surgery were randomly divided into three groups averagely: control group (groupⅠ), controlled hypotension with nitroglycerin group(group Ⅱ), controlled hypotension with nitroglycerin and esmolol group (groupⅢ). Every group has 20 patients.Mean artery pressure (MAP), HR, scores of surgical field quality(SSFQ) were recorded before anaesthesia and 10,20,30,40 minutes after anaesthesia. After the operation, bleeding capacity, operation time and dosage of nitroglycerin were recorded too.Results The bleeding capacity and operation time in groupⅡ and Ⅲ was significantly less than that in groupⅠ(P

The antiarrhythmic actions of ZnSO4 (Zinc) were studied in ex-perimental arrhythmias models. ZnSO4 10mg/kg(iv) significantly coun-teracted the arrhythmias, induced by aconitine or BaCl2 rats.It was shown to shorten the duration of arrhythmias induced by chloroform-epinephrine in rabbits. In mice, ZnSO4 20 ?g/10g(ip) decreased the incidence of ventricular fibrillationbychloroform. However, ZnSO4 did not decrease the incidence of CaCl2-induced , venticular fibrillation, the threshold and lethal doseofouabain in producing ventricular permature beats, ventricular fibrillation in guinea pigs.

Zinc sulfate 0.1mmol/L inhibited the frequency dependent positive staircase phenomenon on isolated guinea pig atria. Ten min after adding zinc sulfate 0.1 mmol/L, the contractility of the left atrium decreased. The needed concentration of epinephrine inducing automaticity was increased and the functional refractory period(FRP) was prolonged from 192?5 ms to 247?4 ms ( P

The effects of Na_2MoO_4 on experimental ventricular arrhythmias and isolated guinea pig atria are reported. Iv Na_2MoO_4, 8 mg/kg was found to increase the tolerant dose of ouabain to produce ventricular permature beats, ventricular tachycardia and ventricular fibrillation in guinea pigs. Na_2MoO_4 significantly counteracted the ventricular arrhythmias induced by BaCl_2 and aconitine in rats. Na_2MoO_4 10 ?g/10 g ip decreased the incidence of ventricular fibrillation by chloroform in mice, Na_2MoO_4 10 mg/kg did not produce antagonistic effect on the arrhythmias induced by chloroform-adrenaline in rabbits. Na_2MoO_4 0.1 mmol/L inhibited contractility of isolated guinea pig atria, prolonged the functional refractory period and makedly inhibited the frequency-dependent positive staircase phenomenon and the post-rest potentiation.

Objective To study the distribution and antimicrobial susceptibilities of anaerobic bacteria from periodontal pockets of patients with chronic periodontitis, so as to guide the anti-infection therapy. Methods Eighty-four patients with chronic periodontitis were enrolled in this study. The anaerobes were isolated from periodontal pockets of patients with chronic periodontitis. Antimicrobial susceptibility of the anaerobes to seven kinds of antibiotics (like metronidazole, penicillin, cefmetazole, etc.) was tested with the agar dilution technique. Results A total of 305 cultivable anaerobes were isolated from periodontal pockets of 84 patients with chronic periodontitis. All patients were infected by anaerobes. 59.34%of cultivable anaerobes were gram-positive anaerobes, and 40.66%were gram-negative anaerobes. The P.melanin ogenica and P.gingivalis were the most common among the cultivable anaerobes, accounting for 51.19% and 55.95%, followed by P.intermedia (36.90%), P.micros (35.71%), F.mucleatum (33.33%), Capnocytophaga ssp (27.38%), Actinomyces ssp (10.71%), and so on. Most isolated anaerobes were sensitive to seven antibiotics. All isolated anaerobes were susceptible to Chloromycetin and Imipenem. 98.03%of isolated anaerobes were susceptible to Amoxicillin. Approximately 76%to 88%of isolated anaerobes were susceptible to Cefmetazole and Metronidazole. Susceptibility to Clindamycinum and Penicillin were 65.91%and 55.73%. Conclusions There is a close relationship between chronic periodontitis and anaerobes. P.melanin ogenica and P.gingivalis are the most frequently isolated anaerobes from periodontal pockets of patients with chronic periodontitis. Chloromycetin and Imipenem can be used for the treatment of anaerobes infected chronic periodontitis.

0.05),while we found significant difference in hospital duration between more than 60 days group and less than 30 days group(P

Objective To analyze the quality control of the conformal radiotherapy for nasopharyngeal carcinoma. Methods Using BJ-6 6MV linear accelerator, STAR -2000 3D TPS and immobilization device, the patient of nasopharyngeal carcinoma were treated by the conformal radiotherapy. Results Adopting individualized compatibly-shaped face masks and CT scanning (2mm interval, 2mm thickness), three dimensional data of the target and the other tissues were acquired. The conformal radiotherapy was designed in planning system. At the treatment, the target volume was put on the isocenter of the linear accelerator by the customized patient positioning. Conclusion Because the nasopharyngeal carcinoma is located in a special area and it is surrounded by some important organ, in the conformal radiotherapy, the quality control of the CT immobilization technique and the customized patient positioning is very important. This can ensure effective and safe irradiation for the small target volume while excessive irradiation is avoided in other surrounding organs.