1.Ethic thinking on the medical privacy of SARS patients
Chinese Medical Ethics 1994;0(05):-
There is a contradictory between patients' privacy on his condition and the public' civil of knowing facts in the course of preventing and treating SARS.The contradictory should be argued in favor of ethics and be supported by social psychology.
2.Research progress on mechanisms of arsenic trioxide in treating lymphoma
Li MA ; Liang-Ming MA ;
Cancer Research and Clinic 1999;0(05):-
Now the treatment of lymphoma mainly uses combined chemotherapy and radiotherapy.Es- pecially hemopoietic stem cell transplantation is effective in the treatment to the patients with refractory and later stage.During the recent years the domestic and foreign scholars have obtained the encouraging results with arsenic trioxide to treat lymphoma.This article has reviewed the experimental study and the clinical re- search progress about arsenic trioxide in application to lymphoma cells.
3.Study on the processing of silk biomaterial and its application in tissue engineering
International Journal of Biomedical Engineering 2008;31(3):188-191
Silk fiber,as a kind of natural polymer,has been used as surgical sutures in clinic for years.Silk fiber is composed of a filament core protein,termed fibroin and a glue-like coating called sericin proteins.Due to its unique mechanical properties,good biocompatibility and slow degradability,silk fiber has been put in variety of applications as a new kind of biomedical scaffolds in recent years.With the development of the processing technique,silk fiber can be processed through the new versatile processing method to form various forms of scaffolds and its surface could be modified for different purposes.Further more,it could be tailored through genetic recombination to form the silk fibroin-like polymers which has a promising potential in medical applications.
4.Biomarkers of lung cancer micro-metastasis and their detection
Journal of International Oncology 2011;38(1):39-42
Micrometastasis is small metastasis at the cellular and molecular level. Early detection of micrometasis through tumor markers can improve the accuracy of TNM staging, prognosis and subsequently treatment for lung cancer patients. Currently, a number of markers with good specificity and sensitivity have been found, including CK19 mRNA, Lunx mRNA, MUC1 mRNA and GPRP mRNA. These markers can be detected using methods such as RT-PCR, immunohistochemistry and western blot.
5.Design of USB Bus power circuits for neuromuscular rehabilitator
Chinese Medical Equipment Journal 2004;0(09):-
This paper analyses the characteristics of USB bus power.Based on the power demand of the circuits for neuromuscular rehabilitator,power voltage transformation circuits are designed for the realization of USB bus power supply.
6.Granulocyte colony-stimulating factor and hematonosis
Chinese Journal of Tissue Engineering Research 2007;0(14):-
Granulocyte colony-stimulating factor is a glycosylated polypeptide chain cell growth factor that can promote proliferation and differentiation of myeloid progenitors and induce maturation of these cells toward terminally differentiated neutrophils.Granulocyte colony-stimulating factor which functions and effects depend on the combination with specific receptor on the surface of effector cells.With the development of gene cloning technology,ganulocyte colony-stimulating factor recombinant products have been widely used in clinic to provide effective means for the treatment of leucopenia,In recent years,we find the therapy of chemotherapeutics combining with granulocyte colony-stimulating factor is effective in refractory/relapsed/elderly cases of acute leukaemia.Currently,granulocyte colony-stimulating factor is one of important and successful hematopoietic cytokines in clinic.
7.Nosocomial Infections with Acinetobacter baumannii:Clinical Distribution and Drug Resistance
Chinese Journal of Nosocomiology 1994;0(01):-
OBJECTIVE To approach the clinical distribution and drug resistance in nosocomial infections with Acinetobacter baumannii(ABA) to provide the scientific evidence for clinical diagnosis and treatment.METHODS Referring to National Rules of Operation in Clinical Laboratory,215 strains of ABA were isolated.Microscan auto-4 was used to identify strains.And the antibiotic susceptibility test was performed by K-B method.The test results were judged according to CLSI 2007.RESULTS The top four of isolated rates were the intensive care unit(23.3%),department of neurology(17.7%),department respiratory medicine(15.8%) and department of tumor(14.4%).The detection rate of ABA from specimen from respiratory tract was the highest,arriving at 72.6%.The antibiotic susceptibility test showed ABA had been resistant to commonly used antibiotics.The resistance rates to imipenem and meropenem were 22.3% and 23.7%,respectively.The isolated rate of pan-resistant stains was 7.4%.CONCLUSIONS Hospitals should think highly of monitoring and controlling of drug resistance in ABA and prevent nosocomial infections with multidrug resistant strains.
8.The significance of DNA-RNA double parameter quantitative analysis in the early diagnosis of laryngeal squamous cell carcinoma
Journal of Third Military Medical University 1988;0(05):-
The relative content of DNA-RNA and the nuclear area/nucleolar area ratio of the hyperplastic tissue,glottic polypus,dysplastic tissue of grade I to I laryngeal squamous cell carcinoma were measured in 33 cases with image analysis technique.It was found that the changes of DNA-RNA content and the ratio of nuclear/nucleolar area were parallel to those of the severity of the carcinoma,and RNA was markedly increased in grade 11 and I dysplastic tissue.On the basis of the current grading of laryngeal pathology,the combined determination of DNA-RNA can provide more sensitive indicators to the stages of malignant degeneration of the laryngeal squamous cell carcinoma.
9.Preventive Effect of Flurbiprofen Axetil or Small-Dose Ketamine for Remifentanil-induced Postoperative Hyperalgesia
Journal of Kunming Medical University 2014;(1):106-108
Objective The purpose of this study was to investigate the preventive effect of flurbiprofen axetil or small-dose ketamine for remifentanil-induced postoperative hyperalgesia. Methods 120 anesthetized patients with ASA ⅠorⅡwere randomly divided into three groups. Group A (40 cases) was given 0.5 mg/kg of ketamine by intravenous injection,and 5μg/(kg.min) vein to maintain,group B (40 cases) was given 100 mg of preoperative flurbiprofen axetil by intravenous injection and group C (40 cases) had no flurbiprofen axetil or ketamine which was served as controls. After the treatment, all groups were given continuous intravenous tramadol controlled analgesia (PCIA) . Results After 1 h, 2 h, 4 h and 8 h, the visual analog scale (VAS) of group C was significantly higher than that of group A and group B ( <0.05);after 24 h, there was no statistically significant difference among the three groups in VAS scores ( > 0.05) . The number of fentanyl analgesia were 25 cases and postoperative 24 h PCIA self-control were (8.6 ±4.2) times, which were more than 7 cases and (3.3 ±2.8) times of group A, and 6 cases and (3.2 ± 2.2) times of group B ( <0.05) . Conclusion The preoperative administration of flurbiprofen axetil or intraoperative continuously administered ketamine is able to prevent the occurrence of remifentanil-induced postoperative hyperalgesia, and it will not affect the patient regained consciousness. The method is safe and reliable,so it is worth promoting and popularizing.
10.Therapy for moderate and advanced liver carcinoma
Journal of International Oncology 2012;39(8):612-615
Due to the latent and highly invasive characteristics of liver carcinoma,a majority of patients are frequently not diagnosed until moderate or advanced stage in the disease process,and usually complicate with cirrhosis.Only 15% -30% of the patients are eligible for radical resection.The overall survival time is about 3-4 months.Therefore,on the basis of early diagnosis and treatment of liver carcinoma,how to improve the treatment effect of the moderate and advanced liver carcinoma,ameliorate the quality of life and prolong the survival time,becomes the focuses and difficulties both at home and abroad.