1.Sentinel Lymph Node Navigation Surgery for Early Gastric Cancer: Is It a Safe Procedure in Countries with Non-Endemic Gastric Cancer Levels? A Preliminary Experience.
Guilherme Pinto BRAVO NETO ; Elizabeth Gomes DOS SANTOS ; Felipe Carvalho VICTER ; Marcelo Soares NEVES ; Márcia Ferreira PINTO ; Carlos Eduardo De Souza CARVALHO
Journal of Gastric Cancer 2016;16(1):14-20
PURPOSE: Early diagnosis of gastric cancer is still the exception in Western countries. In the East, as in Japan and Korea, this disease is an endemic disorder. More conservative surgical procedures are frequently performed in early gastric cancer cases in these countries where sentinel lymph node navigation surgery is becoming a safe option for some patients. This study aims to evaluate preliminary outcomes of patients with early gastric cancer who underwent sentinel node navigation surgeries in Brazil, a country with non-endemic gastric cancer levels. MATERIALS AND METHODS: From September 2008 to March 2014, 14 out of 205 gastric cancer patients underwent sentinel lymph node navigation surgeries, which were performed using intraoperative, endoscopic, and peritumoral injection of patent blue dye. RESULTS: Antrectomies with Billroth I gastroduodenostomies were performed in seven patients with distal tumors. The other seven patients underwent wedge resections. Sentinel basin resections were performed in four patients, and lymphadenectomies were extended to stations 7, 8, and 9 in the other 10. Two patients received false-negative results from sentinel node biopsies, and one of those patients had micrometastasis. There was one postoperative death from liver failure in a cirrhotic patient. Another cirrhotic patient died after two years without recurrence of gastric cancer, also from liver failure. All other patients were followed-up for 13 to 79 months with no evidence of recurrence. CONCLUSIONS: Sentinel lymph node navigation surgery appears to be a safe procedure in a country with non-endemic levels of gastric cancer.
Biopsy
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Brazil
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Early Diagnosis
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Gastrectomy
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Gastroenterostomy
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Humans
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Japan
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Korea
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Liver Failure
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Lymph Node Excision
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Lymph Nodes*
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Neoplasm Micrometastasis
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Recurrence
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Sentinel Lymph Node Biopsy
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Stomach Neoplasms*
2. Acaricidal activity of Derris floribunda essential oil and its main constituent
Ana Claudia Fernandes AMARAL ; Aline de S. RAMOS ; José Luiz Pinto FERREIRA ; Márcia Reis PENA ; Neliton Marques DA SILVA ; Jean Michel S. MENEZES ; Jefferson Rocha de Andrade SILVA ; Geraldo J.N. VASCONCELOS
Asian Pacific Journal of Tropical Biomedicine 2017;7(9):791-796
Objective To evaluate the acaricidal activity of the essential oil obtained from roots of Derris floribunda (D. floribunda) (Miq.) Benth, and its main constituent nerolidol against the Mexican mite Tetranychus mexicanus (T. mexicanus) (McGregor). Methods The essential oil from the roots of D. floribunda collected in the Amazon region (Brazil) was obtained by hydrodistillation. Its chemical composition was determined by GC–MS analysis. The acaricidal activities of this essential oil and nerolidol, were evaluated by recording the number of dead females (mortality) and eggs (fertility). Results The essential oil showed sesquiterpenes as major volatile components. Nerolidol, the main component, represented 68.5% of the total composition of the essential oil. D. floribunda essential oil and nerolidol showed acaricidal activity, with LC