Drug hypersensitivity syndrome (DHS) is an idiosyncratic systemic reaction to a drug. The clinical presentation of this syndrome comprises a diverse spectrum, ranging from mild to fulminating organ failure. Nonspecific gastrointestinal symptoms are common in DHS, but severe morbidities and mortalities attributed to gut disease in DHS are rarely described. We present a case of DHS with significant gastrointestinal symptoms of prolonged profuse watery diarrhoea and persistent hypokalaemia requiring judicious intravenous water and electrolyte replacement. The symptoms resolved only after the introduction of intravenous hydrocortisone. It is important to consider intravenous corticosteroids if the gastrointestinal system is involved, as accelerated gut motility and mucosal damage would affect absorption of oral medications. Supportive treatment with the monitoring of fluid and electrolytes status and judicious replacement remains fundamental in the management of DHS patients with gut involvement.
Amoxicillin-Potassium Clavulanate Combination ; therapeutic use ; Diarrhea ; complications ; diagnosis ; Drug Eruptions ; diagnosis ; drug therapy ; Drug Hypersensitivity Syndrome ; complications ; diagnosis ; Edema ; chemically induced ; Electrolytes ; Female ; Gastrointestinal Diseases ; chemically induced ; complications ; Humans ; Hydrocortisone ; therapeutic use ; Middle Aged ; Otitis Media ; complications ; drug therapy ; Prednisolone ; therapeutic use ; Stomatitis ; chemically induced

Background and aims: Forest bathing or Shinrin-Yoku is a practice of being mindful of nature and it offers multiple health benefits in both physiological and psychological factors. This study aimed to determine the knowledge and attitude of Universiti Kebangsaan Malaysia (UKM) medical students towards forest bathing and its relationship with the sociodemographic factors. Materials and methods: A total of 165 UKM medical students were recruited using proportionate random sampling. The subjects were then categorized based on the academic year (Year 1 - Year 5). Exclusion criteria includes those who deferred their academic year and/or who were hospitalized. A questionnaire was given via a google form consisting of sociodemographic data details and 15 questions for each knowledge and attitude on forest bathing. Results: The prevalence of good knowledge and good attitude of UKM medical students towards forest bathing were 64.2% (n=106) and 50.9% (n=84) respectively. Female medical students had a good knowledge (n=63, 73.3%) and good attitude (n=52, 60.5%) compared to male medical students' knowledge (n=43, 54.4%) and attitude (n=32, 10.5%) leading to a p-value of 0.012 and p-value of 0.010. Otherwise, other sociodemographic factors including race, level of medical year and level of lifestyle did not affect participants' knowledge and attitude on forest bathing. Conclusion Majority of UKM medical students have a higher prevalence of good knowledge compared to good attitude on forest bathing. Therefore, intervention is recommended especially towards male medical students as forest bathing has enough evidence as preventive medicine.