1.A Case of Conjunctival and Lid Lymphedema Confirmed with Lymphoscintigraphy.
Journal of the Korean Ophthalmological Society 1987;28(2):407-411
Lymphedema is due to a defect in lymphatic drainage which may be classified as two types; primary and secondary lymphedema. The authors experienced a case of lymphedema of lower lid and conjunctiva secondary to periorbital trauma and scar revision was done to reduce lymphedema. Lymphoscintigraphy was used to evaluate lymphatic obstruction and result was satisfactory for confirming the disease.
Cicatrix
;
Conjunctiva
;
Drainage
;
Lymphedema*
;
Lymphoscintigraphy*
2.The value of iliopelvic lymphoscintigraphy in the preoperative assessment of lymph node involvement in patients with cervical cancer.
Young Min CHOI ; Jin Wan PARK ; Hyun Jin SONG ; June Key CHUNG ; Myung Chul LEE ; Soon Beom KANG ; Hyo Pyo LEE
Korean Journal of Obstetrics and Gynecology 1991;34(3):376-384
No abstract available.
Humans
;
Lymph Nodes*
;
Lymphoscintigraphy*
;
Uterine Cervical Neoplasms*
3.Sentinel Lymph Node Imaging in Breast Cancer.
Korean Journal of Nuclear Medicine 1999;33(3):243-246
Currently, dissection of the axillary or regional lymph nodes is considered the standard staging procedure in breast cancer. However, accumulating evidence is becoming available that the sentinel node concept may provide the same or even better staging information. In the case of melanoma, it is proven that the histoiogical characteristics of the sentinel node reflect the histological characteristics of the distal part of the lymphatic basin. Morbidity can be reduced significantly by the use of sentinel node dissection as several authors have reported successful introduction of this technique into clinical practice. But in breast cancer patients, there are signigicant differences in practice relating to the technology, such as radiopharmaceuticals, injection sites, volume of injectate, combination with vital blue dye, preoperative lymphoscintigraphy, etc. Valuable reports on these topics appeared in recent journals. This review is a summary of those reports for nuclear physicians interested in sentinel node detection by lymphoscintigraphy in breast cancer patients.
Breast Neoplasms*
;
Breast*
;
Humans
;
Lymph Nodes*
;
Lymphoscintigraphy
;
Melanoma
;
Radiopharmaceuticals
4.A Case of Merkel Cell Carcinoma with Metastasis to Sentinel Lymph Node and Regional Lymph Node Confirmed by Lymphoscintigraphy.
Jae Wook JUNG ; Soo Young KIM ; Ho Jung JUNG ; Hyun Jung PARK ; Hyung Jin HAHN ; Yang Won LEE ; Yong Beom CHOE ; Kyu Joong AHN
Korean Journal of Dermatology 2014;52(1):60-62
No abstract available.
Carcinoma, Merkel Cell*
;
Lymph Nodes*
;
Lymphoscintigraphy*
;
Neoplasm Metastasis*
5.Predicting the Effect of Complex Physical Therapy: Utility of Manual Lymph Drainage Performed on Lymphoscintigraphy.
June Yong JUNG ; Ji Hye HWANG ; Doo Hwan KIM ; Hyeon Sook KIM ; Seung Hyun JUNG ; Peter KW LEE ; June Young CHOI ; Byung Boong LEE ; Dong Ik KIM
Journal of the Korean Academy of Rehabilitation Medicine 2004;28(1):78-82
OBJECTIVE: To evaluate the utility of manual lymph drainage (MLD) during lymphoscintigraphy (LS) in predicting the effect of complex physical therapy (CPT). METHOD: Forty seven patients were included in this study. MLD was done for 30 minutes after one hour LS image was obtained. 24 patients were followed up for 3~6 months. According to one hour LS image, patients were assigned to visible lymph node or lymphatic vessel group (Either group) and invisible lymph node and lymphatic vessel group (Neither group), and also according to LS changes after MLD, good and poor response group. The limb volume was checked before, and immediately after CPT, and at 1 month and 3~6 months after CPT. The treatment response was evaluated by percent volume reduction (PVR). RESULTS: There were no significant differences in volume reduction between Either group and Neither group. Otherwise, good response group showed significantly greater volume reduction after CPT than poor response group. Mean PVR in the good response group was 37.02% immediately after CPT, 41.2% at 1 month after CPT, and 47.4% at 3~6 months after CPT. Mean PVR in the poor response group was 19.22% immediately after CPT, 13.0% at 1 month after CPT, and 5.21% at 3~6 months after CPT. CONCLUSION: LS changes after MLD reflected the effects of CPT more accurately than one hour LS image.
Drainage*
;
Extremities
;
Humans
;
Lymph Nodes
;
Lymphatic Vessels
;
Lymphedema
;
Lymphoscintigraphy*
6.Lymphoscintigraphy of Eyeball and Ocular Adnexal Malignant Tumors.
Chan Soo PARK ; Jun Hyuk SON ; Wha Sun CHUNG ; Ihn Ho CHO
Journal of the Korean Ophthalmological Society 2004;45(6):893-898
PURPOSE: To evaluate the usefulness of preoperative or postoperative lymphoscintigraphy for the identification of lymphatic drainage and sentinel lymph node in patients with eyeball and ocular adnexal malignant tumors. METHODS: Lymphoscintigraphy was performed preoperatively or postoperatively in 5 patients with biopsy proven primary eyeball or ocular adnexal malignant tumors. Patients underwent lymphoscintigraphy with 500 micro Ci of technetium-99m antimony trisulfide colloid in a volume of 0.1 ml. We injected intradermally either the outer 1/3 of the upper or lower lid, or the inner 1/3 of the upper or lower lid. Images were taken by Gamma camera and we checked lymphatic drainage and sentinel lymph nodes. RESULTS: Two patients with conjunctival malignant melanoma showed normal lymphatic drainage, but the other two patients had lymphatic drainage to the parotid and submandibular chain, and sentinel lymph nodes were noted as the parotid lymph node and the submandibular lymph node. The patients with sebaceous gland carcinoma injected in the outer 1/3 of the upper lid had submandibular lymphatic chain and the sentinel lymph node proved to be the submandibular lymph node. CONCLUSIONS: Lymphoscintigraphy demonstrated the lymphatic drainage system and successfully identified the sentinel lymph nodes. This should prove to be very helpful to evaluate metastasis of the eyeball and ocular adnexal malignant tumors by selective lymph node biopsy and to decide the degree of surgery.
Antimony
;
Biopsy
;
Colloids
;
Drainage
;
Gamma Cameras
;
Humans
;
Lymph Nodes
;
Lymphoscintigraphy*
;
Melanoma
;
Neoplasm Metastasis
;
Sebaceous Glands
7.Camparison between the 1 Day and the 2 Day Protocols of Lymphoscintigraphy and Sentinel Node Biopsy using Subareolar Injection in Breast Cancer Patients: A Retrospective Study.
Ju Won SEOK ; Sungmin JUN ; Hyun Yeol NAM ; In Ju KIM
Nuclear Medicine and Molecular Imaging 2009;43(1):55-59
PURPOSE: Lymphoscintigraphy and sentinel node biopsy are used in detection of axillary lymph node metastasis in breast cancer patients, but standardized technique is not established. We compared the results of the injection the morning of surgery (1 day protocol) with the subareolar injection the day before surgery (2 day protocol) with the subareolar injection in patients with breast cancer having lymphoscintigraphy and sentinel node biopsy. MATERIALS AND METHODS: This study included 349 patients who underwent the breast cancer operation during 2001-2004. One hundred seventy one patients (1 day protocol, 1 hour) was injected 0.8 ml of Tc-99m Tin-Colloid (37 MBq) by subareolar injection on the morning of surgery. One hundred seventy eight patients (2 day protocol, 16 hour) was injected 0.8 ml of Tc-99m Tin-Colloid (185 MBq) on the afternoon before surgery. Lymphoscintigraphy was performed in sitting position and sentinel node localization was performed by hand-held gamma probe during operation. Result: In the 1 day protocol, 153 cases (89.5%) of the sentinel node were localized by lymphoscintigraphy and 150 cases (87.7%) were localized by gamma probe. In the 2 day protocol, 159 cases (89.3%) were localized by lymphoscintigraphy and 154 cases (86.5%) were localized by gamma probe. There was no significant difference in localization of sentinel node between the 1 day and the 2 day protocol by lymphoscintigraphy and gamma probe (p>0.05, p>0.05). CONCLUSION: There was no difference the result of localization of sentinel node with subareolar injection between the 1 day and the 2 day protocol in breast cancer patients. Because the 2 day protocol allows the enough time of performing lymphoscintigraphy, it is more useful in localization of sentinel node in breast cancer patients.
Biopsy
;
Breast
;
Breast Neoplasms
;
Humans
;
Lymph Nodes
;
Lymphoscintigraphy
;
Neoplasm Metastasis
;
Nitriles
;
Pyrethrins
;
Retrospective Studies
8.The Efficacy of Sentinel Node Biopsy Using Subareolar Injection of Radioactive Material in Breast Cancer.
Hyun Ah KIM ; Jae Hyuk LEE ; Byung In MOON ; Kum Ja CHOI ; Soon Hee SUNG ; Hye Young CHOI ; Hyun Suk SUH
Journal of Korean Breast Cancer Society 2003;6(3):180-185
PURPOSE: This study was designed to evaluate the feasibility of sentinel node biopsy (SNB) using subareolar injection of radioactive material in breast cancer. METHODS: The prospective study was performed of 112 breast cancers (T1 or T2 stages) at Ewha Womans University Mok-Dong Hospital from February 2001 to June 2003. Patients underwent lymphoscintigraphy using 99mTc sulfur colloid. The feasibility of SNB was assessed through comparison with simultaneous axillary node dissection. RESULTS: All patients were women, and the median age was 46 years. Internal mammary sentinel lymph node was identified in 2 cases (1.8%). The first node was appeared on lymphoscintigraphy around at 10.7 minutes after subareolar injection. Sentinel nodes could be identified in 111 (99.1%) among 112 patients with a gamma probe. The mean number of harvested sentinel nodes were 3.3 and metastasis was noted 80 of 368 nodes (21.7%). False negative rate was 4.1%. CONCLUSION: SNB using subareolar injection of radioactive material could be a alternative method to replace axillary node dissection in T1 or T2 breast cancers, especially in case of clinical node negative patients.
Biopsy*
;
Breast Neoplasms*
;
Breast*
;
Colloids
;
Female
;
Humans
;
Lymph Nodes
;
Lymphoscintigraphy
;
Neoplasm Metastasis
;
Prospective Studies
;
Sulfur
9.Treatment of Malignant Melanoma Using Sentinel Lymph Node Dissection.
Chul Woo KIM ; Dong HUH ; Chong Ju LEE
Korean Journal of Dermatology 2003;41(1):58-64
BACKGROUND: Sentinel lymph node dissection is a new therapeutic strategy of malignant melanoma. There was no clinical study about sentinel lymph node dissection in Korea. OBJECTIVE: Our purpose was to analyze the results of the treatment of malignant melanoma using sentinel lymph node dissection and to compare sentinel lymph node dissection with elective lymph node dissection. METHODS: History of 9 cases with malignant melanoma(1 case treated with elective lymph node dissection and 8 cases treated with sentinel lymph node dissection) at our institution over 2 years were reviewed. We evaluated the clinical & histopathologic data, status of sentinel lymph node and results of treatment. RESULTS: Sentinel lymph nodes were located within the regional lymph node basins in all 8 cases of extremity melanoma, except 1 case(trunk melanoma). Of 8 cases treated with sentinel lymph node dissection, the number of sentinel lymph node was 11, and positive lymph nodes was 3. Patients with positive sentinel lymph node were treated with therapeutic regional lymphadenectomy, chemotherapy and adjuvant therapy. No further treatment or only interferon administration was done in patients with negative sentinel lymph node. CONCLUSION: We confirmed the usefulness of lymphoscintigraphy and sentinel lymph node dissection using vital dye staining in the diagnosis and treatment of lymph node metastasis of melanoma.
Diagnosis
;
Drug Therapy
;
Extremities
;
Humans
;
Interferons
;
Korea
;
Lymph Node Excision*
;
Lymph Nodes*
;
Lymphoscintigraphy
;
Melanoma*
;
Neoplasm Metastasis
10.Sentinel Lymph Node Biopsy and Staging of Melanoma Using Lymphoscintigraphy and Gamma-probe.
Hong Seok KIM ; Ki Hoon SONG ; Seung Joo SIM ; Do Young KANG ; Ki Ho KIM
Korean Journal of Dermatology 2003;41(12):1575-1582
BACKGROUND: In malignant melanoma, the regional nodal status is acknowledged as the most powerful indicator of prognosis. Sentinel lymph node status was formally adopted in 2002 AJCC melanoma staging system. However, there has been no clinical study on sentinel lymph node evaluation, especially using lymphoscintigraphy and gamma probe in melanoma patients in Korea. OBJECTIVE: Our purpose was to assess the usefulness of lymphoscintigraphy and intraoperative gamma probe for the detection of sentinel lymph node in melanoma patients. METHODS: In eight malignant melanoma patients (7 stage I/II, 1 stage III), a lymphoscintigraphy with 99mTc-radiocolloids were injected peritumoral area and the identified first lymph node was considered to be a sentinel node. Once the sentinel lymph node was identified using a hand-held gamma probe for intraoperative mapping, it was excised. And the sentinel node was examined by routine hematoxylin-eosin and immunohistochemical stain (HMB45, S-100). RESULTS: Sentinel nodes were identified in 8 patients all using lymphoscintigraphy and intraoperative gamma probe. Nine sentinel nodes were found in 8 patients, and sentinel lymph node biopsies showed micrometases in 5(55.5%). The location of sentinel nodes was that 3(33.3%) were located in axilla, and 6(66.6%) in groin. The case that had melanoma on back revealed dual lymphatic pathway with 2 sentinel nodes on axilla and inguinal area. CONCLUSIONS: We conclude that preoperative lymphoscintigraphy and intraoperative gamma-probe guided sentinel lymph node biopsy is useful for acute staging and prediction of prognosis for melanoma patients.
Axilla
;
Biopsy
;
Groin
;
Humans
;
Korea
;
Lymph Nodes
;
Lymphoscintigraphy*
;
Melanoma*
;
Prognosis
;
Sentinel Lymph Node Biopsy*