1.A case of infection-associated hemophagocytic syndrome associated with CMV mononucleosis.
Sang Koo KANG ; Suk Bae CHUN ; Man JUNG ; Yung Keun RYOO ; Kwan Soo CHOI ; Ji Woon KIM
Korean Journal of Infectious Diseases 1993;25(4):387-391
No abstract available.
Lymphohistiocytosis, Hemophagocytic*
2.A Case of Virus Associated Hemophagocytic Syndrome.
Yang Soo KANG ; Ue Chong YANG ; Hae Il CHEOUNG ; Ho Jin PARK ; Mi Ja SHIN ; Je Geun CHI
Journal of the Korean Pediatric Society 1989;32(4):567-575
No abstract available.
Lymphohistiocytosis, Hemophagocytic*
3.Etiology, treatment and outcome of children diagnosed with Secondary Hemophagocytic Lymphohistiocytosis in a tertiary hospital
Dianne Loraine P. Clemente ; Robert Dennis J. Garcia
Pediatric Infectious Disease Society of the Philippines Journal 2021;22(1):72-82
Background:
Hemophagocytic lymphohistiocytosis (HLH) is a clinical syndrome that is associated with a variety of underlying conditions leading to the same characteristic hyperinflammatory phenotype.
Objectives:
To describe the clinical profile of patients diagnosed with HLH admitted between January 1, 2010 to September 30, 2019 in a tertiary care hospital.
Methods:
Retrospective descriptive study of pediatric patients diagnosed with HLH in a tertiary care hospital.
Results:
Eleven subjects were included in the study. Age distribution showed a bimodal pattern: < 5 years old (5, 46%) and 10-15 years old (4, 36%). Male to female ratio is 4.5:1. All patients presented with fever (100%) followed by hepatomegaly (5, 45%) and splenomegaly (4, 36%) on physical examination. All eleven subjects fulfilled the following criteria for HLH such as fever, splenomegaly, and hyperferritinemia. Six out of eleven showed hypofibrinogemia (55%) and hypertriglyceridemia (55%). Among the eleven with two cell cytopenia, five presented with anemia (46%), six with neutropenia (55%), while all of them had thrombocytopenia (100%). Other laboratory findings noted were elevated ALT (5, 46%), CRP (4, 36%), AST (3, 27%), alkaline phosphatase (3, 27%), and hyponatremia (3, 27%). EBV and dengue (3, 27%) were the most common etiologies. Pneumonia (3, 27%) was the most common complication, followed by sepsis (2, 18%). All but one patient were responsive to either dexamethasone (7, 64%) and or IVIG (5, 45%) and chemotherapy (1, 9%). The antibiotic most commonly used was piperacillin tazobactam (3, 27%). The median hospital stay was 17 days. There was one mortality (9%).
Conclusion
HLH should be considered in children presenting with prolonged fever, hepatomegaly, and or splenomegaly, with hyperferritinemia, thrombocytopenia, anemia and neutropenia.
Lymphohistiocytosis, Hemophagocytic
4.Hemophagocytic lymphohistiocytosis in adults.
Hyun Jeong LEE ; Min Jeong LEE ; Soo Jeong KIM ; Seung Ho JEONG ; Jeongmin KIM
Korean Journal of Anesthesiology 2014;67(Suppl):S115-S117
No abstract available.
Adult*
;
Humans
;
Lymphohistiocytosis, Hemophagocytic*
5.Disseminated cytomegalovirus-associated hemophagocytic lymphohistiocytosis in an elderly patient.
Preetesh JAIN ; Suhair A AL SALIHI ; Rodrigo HASBUN ; Harinder S JUNEJA ; Nghia D NGUYEN ; Modupe IDOWU
Blood Research 2016;51(4):288-290
No abstract available.
Aged*
;
Humans
;
Lymphohistiocytosis, Hemophagocytic*
6.Hemophagocytic lymphohistiocytosis secondary to histoplasmosis.
B K KARTHIK BOMMANAN ; Shano NASEEM ; Neelam VARMA
Blood Research 2017;52(2):83-83
No abstract available.
Histoplasmosis*
;
Lymphohistiocytosis, Hemophagocytic*
7.A rare case of diffuse large B cell lymphoma-associated hemophagocytic syndrome initially present in the bone marrow with a favorable clinical course.
Sang Hyuk PARK ; Eun Yup LEE ; Joo Seop CHUNG
Blood Research 2016;51(2):144-147
No abstract available.
Bone Marrow*
;
Lymphohistiocytosis, Hemophagocytic*
8.A rare case of diffuse large B cell lymphoma-associated hemophagocytic syndrome initially present in the bone marrow with a favorable clinical course.
Sang Hyuk PARK ; Eun Yup LEE ; Joo Seop CHUNG
Blood Research 2016;51(2):144-147
No abstract available.
Bone Marrow*
;
Lymphohistiocytosis, Hemophagocytic*
9.Two cases of bacteria associated hemophagocytic syndrome in typhoidfever.
Korean Journal of Clinical Pathology 1993;13(1):43-48
No abstract available.
Bacteria*
;
Lymphohistiocytosis, Hemophagocytic*
10.Two cases of bacteria associated hemophagocytic syndrome in typhoidfever.
Korean Journal of Clinical Pathology 1992;12(1):43-48
No abstract available.
Bacteria*
;
Lymphohistiocytosis, Hemophagocytic*
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