1.Extrapulmonary Lymphangioleiomyoma: Clinicopathological Analysis of 4 Cases.
Dae Hyun SONG ; In Ho CHOI ; Sang Yun HA ; Kang Min HAN ; Jae Jun LEE ; Min Eui HONG ; Yoon La CHOI ; Kee Taek JANG ; Sang Yong SONG ; Chin A YI ; Joungho HAN
Korean Journal of Pathology 2014;48(3):188-192
BACKGROUND: Lymphangioleiomyomatosis (LAM) is a slowly progressive neoplastic disease that predominantly affects females. Usually, LAM affects the lung; it can also affect extrapulmonary sites, such as the mediastinum, the retroperitoneum, or the lymph nodes, although these locations are rare. A localized form of LAM can manifest as extrapulmonary lesions; this form is referred to as extrapulmonary lymphangioleiomyoma (E-LAM). Due to the rare occurrence of E-LAM and its variable, atypical location, E-LAM is often difficult to diagnose. Herein, we report the clinicopathological information from four E-LAM cases, and also review previous articles investigating this disease. METHODS: Four patients with E-LAM were identified at the Samsung Medical Center (Seoul, Korea) from 1995 to 2012. All E-LAM lesions underwent surgical excision. RESULTS: All patients were females within the age range of 43 to 47 years. Two patients had para-aortic retroperitoneal masses, while the other two patients had pelvic lesions; two out of the four patients also had accompanying pulmonary LAM. In addition, no patient displayed any evidence of tuberous sclerosis. Histologically, two patients exhibited nuclear atypism with cytologic degeneration. CONCLUSIONS: E-LAM should be considered in the differential diagnosis of patients presenting with pelvic or para-aortic masses. We also conclude that further clinical and pathological evaluation is needed in patients with E-LAM and nuclear atypism.
Abdomen
;
Diagnosis, Differential
;
Female
;
Humans
;
Lung
;
Lymph Nodes
;
Lymphangioleiomyomatosis
;
Lymphangiomyoma*
;
Mediastinum
;
Pelvis
;
Recurrence
;
Tuberous Sclerosis
2.Retroperitoneal Lymphangiomyoma in a Patient with Pulmonary Lymphangiomyomatosis: Case Report.
Jung Wook SEO ; Yoon Jun HWANG ; Soo Young KIM ; Yoon Hee HAN ; Mi Young KIM ; Yong Hoon KIM ; Soon Ju CHA ; Gham HUR
Journal of the Korean Radiological Society 2004;50(5):359-363
Retroperitoneal lymphangiomyoma is rare abdominal finding of lymphangiomyomatosis (LAM). We report here on a case of retroperitoneal lymphangiomyoma and this is the first case that? been seen in the Korean literature. Retroperitoneal lymphangiomyoma associated with pulmonary LAM has rarely been reported in radiologic literature. The charateristic findings of this case are a prominent solid component and retroperitoneal lymphadenopathy mimicking a malignant tumor. A 45-year-old woman was admitted for further evaluation of a lower abdominal mass that could be palpated for 2 weeks. US findings showed relatively well-defined mass with septated cystic portions and echogenic solid portions in the lower abdomen. CT findings revealed a well-demarked retroperitoneal mass with septated cystic portions and enhancing solid portions at the right lower abdomen, and there were multiple retroperitoneal lymphadenopathy at the lower abdomen. The patient underwent a mass excision. The pathologic findings were retroperitoneal lymphangiomyoma with multiple lymph node involvement.
Abdomen
;
Female
;
Humans
;
Lymph Nodes
;
Lymphangioleiomyomatosis*
;
Lymphangiomyoma*
;
Lymphatic Diseases
;
Middle Aged
3.Chylopericardium Secondary to Lymphangiomyoma - A case report -.
Seongmin KO ; Yang Haeng LEE ; Kwang Hyun CHO ; Young Chul YOON ; Il Yong HAN ; Kyung Taek PARK ; Soo Jin JUNG
The Korean Journal of Thoracic and Cardiovascular Surgery 2011;44(5):377-379
Chylopericardium is a rare disease entity characterized by the accumulation of chylous fluid in the pericardial sac. It usually arises from mediastinal neoplasms, thrombosis of the subclavian vein, tuberculosis, nonsurgical trauma, thoracic or cardiac surgery. The spectrum of symptoms for chylopericardium varies from an incidental finding of cardiomegaly to dyspnea, upper abdominal discomfort, cough, chest pain, palpitation, fatigue. However, most of the patients are asymptomatic. The main purpose of treatment of chylopericardium is the prevention of cardiac tamponade and prevention of metabolic, nutritional, and immunological compromise due to chyle leak. Here, we report a case of chylopercardium secondary to lymphangiomyoma with review of the literature.
Cardiac Tamponade
;
Cardiomegaly
;
Chest Pain
;
Chyle
;
Cough
;
Dyspnea
;
Fatigue
;
Humans
;
Incidental Findings
;
Lymphangioma
;
Lymphangiomyoma
;
Mediastinal Neoplasms
;
Pericardial Effusion
;
Rare Diseases
;
Subclavian Vein
;
Thoracic Surgery
;
Thorax
;
Thrombosis
;
Tuberculosis
4.Pulmonary lymphangioleiomyomatosis in a male.
Hyun Wook KANG ; Chang Jin KIM ; Sang Kook LEE ; Kyung Soo LEE ; Chul Sae LEE ; Yong Hoon KIM
Journal of Korean Medical Science 1991;6(1):83-85
Pulmonary lymphangioleiomyomatosis has been observed almost exclusively in women, usually in their reproductive years. Exacerbations with pregnancy and after hormonal manipulation have been documented, and it has been suggested that its pathogenesis is due to the influence of hormonal(estrogenic) stimulus. The clinical, roentgenographic, and histopathologic features of this case of pulmonary lymphangioleiomyomatosis in a 22-year-old male are all characteristic of those described in prior reports, except for the patient's sex. With the following case of pulmonary lymphangioleiomyomatosis in a male, we suggest the possibility of the existence of an additional pathogenetic mechanism.
Adult
;
Emphysema/complications
;
Humans
;
Lung Neoplasms/complications/etiology/*pathology
;
Lymphangiomyoma/complications/etiology/*pathology
;
Lymphatic System/pathology
;
Male
;
Muscle, Smooth/pathology
;
Thoracotomy/adverse effects
;
Tuberculosis, Pulmonary/complications
5.Pulmonary lymphangiomyomatosis.
Soo Sang JUNG ; Byeng Ryul PARK ; Jong Su LEE ; Seok Sung YANG
The Korean Journal of Thoracic and Cardiovascular Surgery 1993;26(2):160-163
No abstract available.
Lymphangioleiomyomatosis*
6.Pulmonary lymphangioleiomyomatosis: case reports.
Kyung Soo LEE ; Eun Wan CHOI ; Byoung Ho LEE ; Won Kyung BAE ; Yong Hoon KIM ; Chang Jin KIM ; Joong Kee NOH
Journal of the Korean Radiological Society 1991;27(2):240-244
No abstract available.
Lymphangioleiomyomatosis*
7.Pulmonary lymphangioleiomyomatosis: high-resolution CT findings.
Woo Kyung MOON ; Jung Gi IM ; Man Chung HAN
Journal of the Korean Radiological Society 1991;27(4):543-546
No abstract available.
Lymphangioleiomyomatosis*
8.Lymphangioleiomyomatosis in Korea.
Eun Kyung MO ; Man Pyo JUNG ; Chul Gyu YOO ; Young Whan KIM ; Sung Koo HAN ; Jung Gi IM ; Jeong Wook SEO ; Seung Sook LEE ; Young Soo SHIM ; Keun Youl KIM ; Yong Chol HAN
Tuberculosis and Respiratory Diseases 1993;40(5):519-531
No abstract available.
Korea*
;
Lymphangioleiomyomatosis*
9.Pulmonary lymphangioleiomyomatosis in Pham Ngoc Thach Hospital: a case report
Ho Chi Minh city Medical Association 2003;8(2):104-106
This rare condition was diagnosed in the stage of a history of resection of left renal tumor of angiomyolipoma and recurrant pneumothrax with PCR of positive tuberculosis bacilla, special chest CT scan with thin wall cyst. These female patients are in reproductive age, using consistantly sex hormone. The prognosis is similar with COPD. Early detection and treatment of the case slowers the progression of disease.
Lymphangioleiomyomatosis
;
Lung
;
Disease
10.Two cases of pulmonary lymphangioleiomyomatosis associated with tuberous sclerosis.
Jeong Cheon AHN ; Weon Yong JOH ; Kwang Ho IN ; Kyung Ho KANG ; Se Hwa YOO
Tuberculosis and Respiratory Diseases 1992;39(6):542-547
No abstract available.
Lymphangioleiomyomatosis*
;
Tuberous Sclerosis*