Near-infrared (NIR) fluorescence imaging provides a safe and cost-efficient method for immediate data acquisition and visualization of tissues, with technical advantages including minimal autofluorescence, reduced photon absorption, and low scattering in tissue. In this review, we introduce recent advances in NIR fluorescence imaging systems for thoracic surgery that improve the identification of vital tissues and facilitate the resection of tumorous tissues. When coupled with appropriate NIR fluorophores, NIR fluorescence imaging may transform current intraoperative thoracic surgery methods by enhancing the precision of surgical procedures and augmenting postoperative outcomes through improvements in diagnostic accuracy and reductions in the remission rate.
Absorption ; Fluorescence ; Lymph Nodes ; Methods ; Optical Imaging ; Thoracic Surgery

Axilla ; Breast Neoplasms ; pathology ; surgery ; Female ; Humans ; Lymph Node Excision ; Lymph Nodes ; pathology ; surgery

Lymph node metastasis is an important route of metastasis of lung cancer. Lymphadenectomy has become the standard surgical procedure for lung cancer. The way of intraoperative lymph node assessment also affects the prognosis and treatment strategy of lung cancer. In clinical practice, the way of intraoperative lymph node assessment ranges from selected lymph node biopsy to extended lymph node dissection. The advantages and disadvantages of different lymph node assessment are still controversial. In this article, the argument and consensus of lymphadenectomy on lung cancer operation are summarized.
Humans ; Lung Neoplasms ; pathology ; surgery ; Lymph Node Excision ; Lymph Nodes ; pathology ; surgery ; Lymphatic Metastasis ; Neoplasm Staging

Standardized surgical management of postoperative specimens of gastric cancer is an important part of the standardized diagnosis and treatment of gastric cancer. It can reflect the accurate number and detailed distribution of lymph nodes in the specimen and lay the foundation for accurate and standardized pathological reports after surgery. Meanwhile, it can evaluate the scope of intraoperative lymph node dissection, the safety of cutting edge, and the standardization of surgery (principle of en-bloc dissection), which is an important means of surgical quality control. It also provides accurate research samples for further research and is an important way for young surgeons to train their clinical skills. The surgical management of postoperative specimens for gastric cancer needs to be standardized, including specimen processing personnel, processing flow, resection margin examination, lymph node sorting, measurement after specimen dissection, storage of biological specimens, documentation of recorded data, etc. The promotion of standardized surgical management of specimens after radical gastrectomy can promote the homogenization of gastric cancer surgical diagnosis and treatment in medical institutions and further promote the high-quality development of gastric cancer surgery in China.
Gastrectomy ; Humans ; Laparoscopy ; Lymph Node Excision ; Lymph Nodes/surgery* ; Stomach Neoplasms/surgery*

Splenic flexure colon cancer occurs at a relatively lower rate than colon cancer of other sites. It is also associated with more advanced disease and higher rate of acute obstruction. The splenic flexure receives blood supply from both superior and inferior mesenteric arteries (SMA and IMA), and therefore has lymphatic drainage to both areas. The blood supply is also highly variable, causing difficulties in determining the main feeding vessels and the main direction of lymph drainage. Few studies with limited cases focused on this specific tumor site with respect to the patterns of lymph node spread, especially the main lymph node status and the value of its dissection. The lack of information limits the development of a consensus on the extent of surgical resection and lymphadenectomy. Adequate mobilization of the colon facilitates a sufficient length of bowel resection and the high ligation of feeding arteries from both SMA and IMA. Further evidence on the chnoice of procedures and the extent of lymph node dissection need multicenter collaboration, with the use of modern techniques, including CT 3D reconstruction of the colon and angiography, as well as intraoperative fluorescent real-time imaging of lymph nodes.
Colon, Transverse/surgery* ; Colonic Neoplasms/surgery* ; Humans ; Laparoscopy ; Lymph Node Excision/methods* ; Lymph Nodes/pathology* ; Mesenteric Artery, Inferior/surgery*

Cervical cancer is a common gynecologic malignancy. Most patients with early-stage cervical cancer received unnecessary systemic pelvic lymphadenectomy, which increased the risk of surgical complications. At present, sentinel lymph node biopsy has been applied in the clinical practice of cervical cancer abroad, however it is still at the starting stage in China in need of application and promotion. The Obstetrics and Gynecology Committee of Chinese Research Hospital Association invited domestic experts in the field of gynecologic oncology to discuss the application value, patient evaluation, technical methods, operation steps, pathological examination and many other key points of sentinel lymph node biopsy based on the current research status, and reached the consensus of clinical application on sentinel lymph node biopsy in cervical cancer to guide the standardized application of the technique in China.
Consensus ; Female ; Humans ; Lymph Node Excision ; Lymph Nodes/surgery* ; Lymphatic Metastasis ; Neoplasm Staging ; Sentinel Lymph Node/surgery* ; Sentinel Lymph Node Biopsy ; Uterine Cervical Neoplasms/surgery*

OBJECTIVEInvestigate the best surgical resection of esophageal cancer by comparing the efficacy and safety between Ivor-Lewis esophagectomy and Sweet esophagectomy.

METHODSThe relevant literatures comparing Ivor-Lewis esophagectomy with Sweet esophagectomy were searched through PubMed, Embase, the Cochrane Library, Google scholar, CNKI, CBM, VIP, WanFang Data. RevMan 5.2 software was used for data analysis.

RESULTSA total of 4106 patients in 15 studies were reviewed and the data were pooled for analysis. Meta-analysis showed that, compared with the Sweet group, Ivor-Lewis operative time was significantly longer(pooled mean difference=57.40; 95%CI:42.43 to 72.38; P=0.000), operative bleeding was significantly higher(pooled mean difference=28.39, 95%CI:4.06 to 52.72, P=0.02); the number of lymph node dissection significantly more(pooled mean difference=4.19, 95%CI:3.06 to 5.32, P=0.000); No significant difference was present in hospital stay, vocal cord paralysis, chylous leakage, pulmonary complications, anastomotic leakage(all P>0.05). The 5-year survival between the two groups showed no significant difference(P=0.52).

CONCLUSIONSThe two kinds of operation have the same long term effect. Compared with Ivor-Lewis operation, Sweet operation is easier to perform, less time consuming and more tolerable. Ivor-Lewis operation can dissect more lymph nodes than Sweet operation, without increased complications.

Laparoscopic D2 lymphadenectomy for locally advanced upper-third gastric cancer(LAUGC) must follow the same lymph node dissection extent with open surgery. Following the surgical steps can make the operation process more smoothly and achieve en bloc resection. Laparoscopic spleen-preserving splenic hilar lymph node dissection is the difficult point during total gastrectomy for LAUGC. Selecting the right surgical approach, mastering spleen vascular anatomical types, and the cooperation of surgical team can help to shorten the learning curve of the operation. Although laparoscopic lymph node dissection for LAUGC is still in the exploratory stage, we believe that with the emergence of evidence-based medicine, it is expected to become one of the standard operations for LAUGC.
Gastrectomy ; Humans ; Laparoscopy ; methods ; Learning Curve ; Lymph Node Excision ; Lymph Nodes ; Spleen ; Stomach Neoplasms ; pathology ; surgery

Laparoscopic spleen-preserving splenic hilar lymphadenectomy (LSPL) is a operation conducted experimentally in the current. Current reports showed that it can be safely completed through different approach, such as the right, left, medial and retropancreatic approach. This paper summarized the steps and characteristics of different approaches LSPL and compared the differences between each other. The application status of LSPL in laparoscopy-assisted radical gastrectomy were reviewed. The security, feasibility and the problem to be solved of LSPL, improvement measure also be explored in this paper.
Gastrectomy ; methods ; Humans ; Laparoscopy ; Lymph Node Excision ; methods ; Lymph Nodes ; Spleen ; Stomach Neoplasms ; surgery

At present, there is still no general consensus on the thoracic lymph node classification and dissection standard of esophageal cancer, and its indications, surgical approaches, harvested number and scopes are still the debated focuses in the academic circle. Therefore, the Society of Esophageal Tumor, Chinese Anti-Cancer Association organized experts in the field to write the Chinese expert consensus on mediastinal lymph node dissection in esophagectomy for esophageal cancer (2017 edition) based on clinical experience and current available evidence. This article focuses on the surgical approach and recurrent laryngeal nerve lymph node dissection in esophageal cancer. The right thoracic approach is recommended for wide application in clinical practice by the authors because of the high resection rate and the advantages of more stations and higher number. But the left thoracic approach should not be eliminated and can be used cautiously to some particular patient. Because the metastatic rate of bilateral recurrent laryngeal nerve lymph node in thoracic esophageal cancer is very high, it is classified as the first and the second group of thoracic lymph nodes. Hence, the authors strongly recommend that bilateral recurrent laryngeal nerve lymph node dissection should be performed for all the esophageal cancer patients. The 3-field or 2 and a half field dissection can be performed by right thoracic approach. The bilateral recurrent laryngeal nerve lymph nodes must be cleaned, and the decision of neck dissection should be made accordingly.
Consensus ; Esophageal Neoplasms ; surgery ; Esophagectomy ; Humans ; Lymph Node Excision ; Lymph Nodes ; Lymphatic Metastasis ; Retrospective Studies