1.Response to comment on “Hypogonadotrophic hypogonadism due to a mutation in the luteinizing hormone β-subunit gene”.
The Korean Journal of Internal Medicine 2017;32(3):568-568
No abstract available.
Hypogonadism*
;
Lutein*
;
Luteinizing Hormone*
2.Comment on “Hypogonadotrophic hypogonadism due to a mutation in the luteinizing hormone β-subunit gene”.
Hernan VALDES-SOCIN ; Adrian F DALY ; Albert BECKERS
The Korean Journal of Internal Medicine 2017;32(3):566-567
No abstract available.
Hypogonadism*
;
Lutein*
;
Luteinizing Hormone*
3.Hypogonadotrophic hypogonadism due to a mutation in the luteinizing hormone β-subunit gene.
Jae Won SONG ; Hyo Jeong HWANG ; Chang Min LEE ; Gun Ha PARK ; Chul Sik KIM ; Seong Jin LEE ; Sung Hee IHM
The Korean Journal of Internal Medicine 2018;33(3):638-641
No abstract available.
Hypogonadism*
;
Lutein*
;
Luteinizing Hormone*
4.A case of idiopathic precocious puberty treated with a luteinizing hormone relaeasing hormone analog.
Keun Hee CHUNG ; Yoo Mi KIM ; Mi Won KIM ; Soon Ki KIM ; Moon Soo PARK ; Jin Keun CHANG
Journal of the Korean Pediatric Society 1991;34(8):1132-1138
No abstract available.
Lutein*
;
Luteinizing Hormone*
;
Puberty, Precocious*
5.LH-Beta Gene Analysis in Infertility Patients.
Jung Yeon KIM ; Gee Hyun PARK ; Sang Wook BAE ; Byung Suk LEE ; Yong Ho AN
Korean Journal of Obstetrics and Gynecology 2000;43(8):1389-1393
No abstract available.
Humans
;
Infertility*
;
Luteinizing Hormone, beta Subunit*
6.Analysis of gonadotropin-releasing hormone (GnRH) test results in girls with precocious puberty.
Jung Yun CHOI ; Hyun Ju KANG ; Won Kyoung CHO ; Kyoung Soon CHO ; So Hyun PARK ; Seung Hoon HAHN ; Min Ho JUNG ; Byung Kyu SUH ; Byung Churl LEE
Korean Journal of Pediatrics 2009;52(12):1377-1382
PURPOSE: The gonadotropin-releasing hormone (GnRH) test results of girls with precocious puberty were analyzed to determine whether this test can efficiently and clearly differentiate between central precocious puberty (CPP) and other disorders. METHODS: Clinical and laboratory data of 54 girls with precocious pubertal signs were reviewed. Intravenous GnRH test was performed with blood samples obtained at 0, 30, 60, and 90 minutes. A peak luteinizing hormone (LH) level of > or =5.0 IU/L was indicative of CPP. RESULTS: Of the 40 girls with CPP, 36 (90.0%), 3 (7.5%), and 1 (2.5%) showed peak LH levels at 30, 60, and 90 minutes, respectively. A percentage of girls whose peak LH > or =5.0 IU/L up to 30, 60, and 90 minutes was 92.5%, 100%, and 100%, respectively. The peak LH/follicle stimulating hormone (FSH) ratio of girls with CPP was 0.89+/-0.49 and was <1 in 16 of the 40 girls (40.0%). Girls with peak LH/FSH ratio of >1.0 showed higher chronological age (CA) (8.3+/-0.6 vs. 7.7+/-1.0 years, P=0.033), bone age (BA) (10.9+/-0.8 vs. 9.7+/-1.1 years, P=0.001), and BA-CA difference (2.6+/-0.7 vs. 2.0+/-0.7 years, P=0.009) than those of girls with peak LH/FSH ratio of < or =1.0. Higher percentage of girls with peak LH/FSH ratio of >1.0 showed advanced breast development (> or =Tanner III) (93.7% vs. 41.7%, P=0.001). CONCLUSION: LH levels after 30 and 60 minutes of intravenous GnRH administration are the most useful for diagnosing CPP in girls.
Breast
;
Gonadotropin-Releasing Hormone
;
Luteinizing Hormone
;
Piperazines
;
Puberty, Precocious
7.The serum level of testosterone, LH, FSH of vasovasostomy patients
Journal of Medical Research 2001;15(2):33-36
The authors announced the level testosterone, LH (Luteinizing hormone), FSH (Follicle Stimulating hormone) in the serum of the patients by ELISA method. Who were done vasectomy. Their age means 36, time of the vasectomy is 5.2 years. Death of their children were major cause. The results mean of the level testosterone, Luteinizing hormone, Follicle Stimulating hormone of the 29 vasovasostomy patients were 18.59% mmol/ml; 10.98 muI/ml; 9.9; 10.98 muI/ml respectively. The levels of testosterone, LH, FSH hadn't had change significant statistics (p>0.05).
Vasovasostomy
;
Testosterone
;
Luteinizing Hormone
;
Follicle Stimulating Hormone
;
serum
9.Follicle-stimulating hormone (FSH) levels prior to prostatectomy are not related to long-term oncologic or cardiovascular outcomes for men with prostate cancer.
Kassim KOURBANHOUSSEN ; France-Hélène JONCAS ; Christopher J D WALLIS ; Hélène HOVINGTON ; François DAGENAIS ; Yves FRADET ; Chantal GUILLEMETTE ; Louis LACOMBE ; Paul TOREN
Asian Journal of Andrology 2022;24(1):21-25
Prior research suggests a link between circulating levels of follicle-stimulating hormone (FSH) and prostate cancer outcomes. FSH levels may also explain some of the observed differences in cardiovascular events among men treated with gonadotropin-releasing hormone (GnRH) antagonists compared to GnRH agonists. This study evaluates the association between preoperative FSH and long-term cardiovascular and oncologic outcomes in a cohort of men with long follow-up after radical prostatectomy. We performed a cohort study utilizing an institutional biobank with annotated clinical data. FSH levels were measured from cryopreserved plasma and compared with sex steroids previously measured from the same samples. Differences in oncologic outcomes between tertiles of FSH levels were compared using adjusted cox regression models. Major adverse cardiovascular events (MACE) were similarly assessed using hospital admission diagnostic codes. A total of 492 patients were included, with a median follow-up of 13.1 (interquartile range: 8.9-15.9) years. Dehydroepiandrosterone sulfate (DHEA-S) levels, but not other androgens, negatively correlated with FSH levels on linear regression analysis (P = 0.03). There was no association between FSH tertile and outcomes of biochemical recurrence, time to castrate-resistant prostate cancer, or time to metastasis. MACEs were identified in 50 patients (10.2%), with a mean time to first event of 8.8 years. No association with FSH tertile and occurrence of MACE was identified. Our results do not suggest that preoperative FSH levels are significantly associated with oncologic outcomes among prostate cancer patients treated with radical prostatectomy, nor do these levels appear to be predictors of long-term cardiovascular risk.
Cohort Studies
;
Follicle Stimulating Hormone
;
Gonadotropin-Releasing Hormone
;
Humans
;
Luteinizing Hormone
;
Male
;
Prostatectomy
;
Prostatic Neoplasms/surgery*
10.Effects of Bushen Yiqi Huoxue Decoction in Treatment of Patients with Diminished Ovarian Reserve: A Randomized Controlled Trial.
Jing ZHOU ; Xin-Yao PAN ; Jin LIN ; Qi ZHOU ; Li-Kun LAN ; Jun ZHU ; Ru DUAN ; Lan WANG ; Yan SUN ; Ling WANG
Chinese journal of integrative medicine 2022;28(3):195-201
OBJECTIVE:
To explore the therapeutic effect of Bushen Yiqi Huoxue Decoction BYHD) in patients with diminished ovarian reserve (DOR).
METHODS:
A total of 180 patients with DOR diagnosed from December 2013 to December 2014 were equally assigned into progynova and duphaston (E+D) group, Zuogui Pill group and BYHD group with 60 cases in each by computerized randomization. Patients received E+D, Zuogui Pill or BYHD for 12 months, respectively. Follicle stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), anti-Müllerian hormone (AMH), antral follicle count (AFC), ovarian volume, endometrial thickness, and the resistance indices (RIs) of ovarian arteries and uterine arteries were observed before and after treatment.
RESULTS:
Nine women (4 from the E+D group, 3 from the Zuogui Pill group, and 2 from the BYHD group) withdrew from the study. After 6 months, Zuogui Pill and BYHD significantly decreased FSH and LH and increased endometrial thickness and AMH (all P<0.01). BYHD also resulted in E2 elevation (P<0.05), ovary enlargement (P<0.05), AFC increase (P<0.01), and RI of ovarian arteries decrease (P<0.05). After 12 months, further improvements were observed in the Zuogui Pill and BYHD groups (all P<0.01), but BYHD showed better outcomes, with lower FSH, larger ovaries and a thicker endometrium compared with the Zuogui Pill group (all P<0.01). However, E+D only significantly increased endometrial thickness (P<0.01) and no significant improvements were observed in the RI of uterine arteries in the three groups.
CONCLUSIONS
BYHD had a favorable therapeutic effect in patients with DOR by rebalancing hormone levels, promoting ovulation, and repairing the thin endometrium. The combination of tonifying Shen (Kidney), benefiting qi and activating blood circulation may be a promising therapeutic strategy for DOR.
Anti-Mullerian Hormone/pharmacology*
;
Drugs, Chinese Herbal
;
Female
;
Follicle Stimulating Hormone
;
Humans
;
Luteinizing Hormone
;
Ovarian Reserve