1.Intracranial hypertension syndrome in systemic lupus erythematosus: clinical analysis and review of the literature.
Zheng, XUE ; Xuezhen, WANG ; Fei, LIU ; Shaoxian, HU ; Suiqiang, ZHU ; Suming, ZHANG ; Bitao, BU
Journal of Huazhong University of Science and Technology (Medical Sciences) 2009;29(1):107-11
In order to better understand the clinical manifestation of systemic lupus erythematosus (SLE) with intracranial hypertension syndrome (IHS), we analyzed the clinical features and treatment of a typical SLE patient with IHS. SLE is one of the most unpredictable autoimmune diseases involving multiple organ systems that is defined clinically and associated with antibodies directed against cell nuclei. IHS is an uncommon manifestation of neuropsychiatric SLE (NPSLE) and is characterized by an elevated intracranial pressure, papilledema, and headache with occasional abducens nerve paresis, absence of a space-occupying lesion or ventricular enlargement, and normal cerebrospinal fluid chemical and hematological constituents. IHS has been reported in a few sporadic cases in patients with SLE worldwide, but rarely has been reported in China. In this study, a 34-year-old female SLE patient with IHS was reported and pertinent literature reviewed. The clinical presentation, image logical features, and investigatory findings were discussed.
Diagnosis, Differential
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Intracranial Hypertension/diagnosis
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Intracranial Hypertension/*etiology
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Lupus Erythematosus, Systemic/*complications
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Lupus Erythematosus, Systemic/diagnosis
4.Systemic Lupus Erythematosus Combined with Chorea: Report of One Case and Literature Review.
Guang-Mei SONG ; Yan-Jie CUI ; Jie QIAO ; Si-Man CAO ; Yi ZHOU ; Li-Hua ZHU
Acta Academiae Medicinae Sinicae 2023;45(1):161-166
Systemic lupus erythematosus combined with chorea is relatively rare in China,and there are no unified diagnostic criteria or specific ancillary tests.Therefore,it is confirmed by exclusionary clinical diagnosis.To improve the understanding of this disease among rheumatologists,we report the clinical data of a patient with systemic lupus erythematosus combined with chorea admitted to the Department of Rheumatology and Immunology in the First Affiliated Hospital of Jinan University in January 2022.Furthermore,we review the relevant literature in the past 10 years and summarize the clinical features of these cases.
Humans
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Chorea/diagnosis*
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Lupus Erythematosus, Systemic/complications*
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China
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Hospitalization
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Hospitals
5.A Case of Systemic Lupus Erythematosus Presenting as Malignant Hypertension with Hypertensive Retinopathy.
Jung Yoon CHOE ; Sung Hoon PARK ; Ji Young KIM ; Hyun Young JUNG ; Seong Kyu KIM
The Korean Journal of Internal Medicine 2010;25(3):341-344
The variability of cardiovascular abnormalities is one of the characteristics of systemic lupus erythematosus (SLE). Among the cardiovascular manifestations, hypertension is reported in 14% to 58.1% of patients in diverse ethnic populations, and remains a clinically important issue due to its close relationship with early mortality in patients with SLE. The development of hypertension in patients with SLE has been associated with advanced lupus-related renal disease and the medications used for the treatment of lupus. Malignant hypertension is a serious complication of hypertension; it rarely occurs in patients with SLE. However, it can occur in patients with other complicated medical conditions such as the antiphospholipid antibody syndrome (APS) or cardiac tamponade. Here, we report the case of a patient with SLE and malignant hypertension with hypertensive retinopathy that initially presented without clinical evidence of APS or hypertensive nephropathy.
Adult
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Female
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Humans
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Hypertension, Malignant/*diagnosis/*etiology
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Lupus Erythematosus, Systemic/*complications/*diagnosis
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Lupus Nephritis/complications/diagnosis
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Retinal Diseases/*diagnosis/*etiology
6.Two Cases of Autoimmnune Hepatitis Associated with Systemic Lupus Erythematosus.
Jang Uk YOON ; Sang Hoon PARK ; Eun Jung KIM ; Ji Hyun HONG ; Hyung Seok LEE ; Kil Chan OH ; Chul Hee PARK ; Tae Ho HAHN ; Dong Keun LEE ; Jong Hyeok KIM ; Hae Lim PARK ; Choong Kee PARK
The Korean Journal of Hepatology 2003;9(3):231-235
Autoimmune hepatitis (AIH) is a chronic necroinflammatory liver disease of unknown cause associated with circulating autoantibodies and high serum globulin level. Systemic lupus erythematosus (SLE) is a disease of unknown etiology in which tissues and cells are damaged by pathogenic autoantibodies and immune complex, affecting multiple organs including the liver, kidney, and CNS. The difference between the hepatic involvement of SLE and autoimmune hepatitis has not been clearly defined in the past due to similarities in clinical and biochemical features. A scoring system for the diagnosis of AIH has been established, and AIH and SLE-associated hepatitis have been defined as two different entities, although both have the same autoimmune features such as polyarthralgia, hypergammaglobulinemia and circulating autoantibodies. AIH has been considered to occur infrequently in SLE. We report two cases of AIH which simultaneously satisfied the criteria of SLE.
Adult
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Female
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Hepatitis, Autoimmune/*complications/diagnosis
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Humans
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Lupus Erythematosus, Systemic/*complications/diagnosis
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Middle Aged
7.Two cases of lupus cystitis and literature review.
Yisha LI ; Hui LUO ; Yanli XIE ; Xiaoxia ZUO
Journal of Central South University(Medical Sciences) 2011;36(8):813-816
OBJECTIVE:
To improve the understanding of lupus cystitis.
METHODS:
Clinical manifestations, laboratory Results , and image information of 2 cases of lupus cystitis were analysed retrospectively, and another 6 cases in the literature were reviewed.
RESULTS:
Two patients were female. The urinary symptoms followed the gastrointestinal symptoms. Ureterectasia and hydronephrosis were detected in both patients, and intestinal pseudo-obstruction was detected in one patient. In the 6 cases from the literature, ureterectasia and hydronephrosis were detected in all patients, and intestinal pseudo-obstruction was detected in 4.
CONCLUSION
The possibility of lupus cystitis should be considered when lupus patients complain of urinary or bowel symptoms. Glucocorticoid and immunodepressant are effective for lupus cystitis.
Adolescent
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Adult
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Cystitis
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complications
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diagnosis
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Female
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Humans
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Hydronephrosis
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etiology
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Lupus Erythematosus, Systemic
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complications
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diagnosis
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Ureter
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pathology
10.Calcification of bilateral ureters: a novel association with systemic lupus erythematosus.
De-Xun JIANG ; Yong LIAO ; Yun-Jing BAI
Chinese Medical Journal 2012;125(12):2235-2237
A 16-year-old female patient with systemic lupus erythematosus (SLE) presented with abdominal pain and oliguria, after one month of hospital treatment with methylprednisolone and cyclophosphamide. Computed tomography of the abdomen revealed the calcification of bilateral superior segmental ureteral wall. Computed tomography urography revealed stenosis of bilateral ureters. This calcification may be associated with lupus-induced inflammatory reaction of ureteral endomembrane. By receiving the ureteral catheters, her abdominal pain and oliguria had been completely resolved. After discharge, she underwent the surgery of cutaneous ureterostomy in the local hospital. During two years follow-up, her condition is stable without any symptom of the urinary system.
Adolescent
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Calcinosis
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diagnosis
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etiology
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Female
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Humans
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Lupus Erythematosus, Systemic
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complications
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Ureter
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pathology