The objective of this study is to obtain a comprehensive understand the view of inservice education master degree program students on their supervisors' performance in teaching and research in Peking University Health Science Centre.on their.This study was conducted by using the questionnaire-based survey which includes questions regarding research quality,research conditions and scientific spirit etc.We concluded that Peking University Health Science Center,by formulating practical regulations and adopting relevant policies,managed to keep the capacity building for the supervisors and will further improve quality of the in-service graduate program.

Actual research on brain-computer interface system is analyzed.The basic structure and operational principle of this system are set forth.Methods of signal collection,feature extraction and selection classification of system signals are concluded.Latest analysis methods and existing defects of feature extraction and selection classification are introduced in detail.Problems existing in brain-computer interface system are also analyzed.Great advantages on feature extraction of wavelet transform & wavelet packet decomposition and wide prospects on selection classification of neural network are pointed out at last.

Objective To investigate the clinical effects and operation key-points of interphalangeal joint replacement arthroplasty for the treatment of traumatic arthritis.Methods From March 2005 to December 2010,5 patients with post-traumatic arthritis undergoing interphalangeal joint replacement arthroplasty in our hospital were selected.The operation indications,treatment of intraoperative flexor and extensor tendon lesion and postoperative rehabilitation were evaluated.Results Operative incisions of 5 cases were primary healing in class I grade A.Stitches were taken out 2 weeks after the operation.Patients were followed up for 1.5 years.The range of interphalangeal joint motion was 0 to 90 (extension/flexion) with no pain at end of follow-up.The hand function was excellent in 3 cases and good in 2 cases according to total active motion (TAM)hand function evaluation.Conclusions Interphalangeal joint replacement arthroplasty is an effective treatment for traumatic arthritis.Preoperative indications evaluation and postoperative rehabilitation should be focused on the treatment.

Objective To investigate the influence of ozagrel sodium (OS) on cerebral ischemic tolerance in rat induced by focal ischemic preconditioning (IPC) and on expression of nuclear factor ?B (NF ?B) in rats Methods Fourty five rats were divided into 3 groups The animals were subjected to 2 h middle cerebral artery occlusion (MCAO) 3 days after 10 min IPC, IPC+OS and sham surgery (SS) respectively. After 22 h reperfusion, the rats were killed and the infarct volume, brain water content and NF ?B immunoreactivity were compared among 3 groups. Results Compared with IPC+ MCAO group, there were a furtber decrements in farct volume (93 75?13 40 vs 130 92?14 59, P

Estrogen receptor(ER),an important transcription factor belonging to the nuclear receptor superfamily,comprises two subtypes ER?and ER?.Estrogen receptor is expressed in prostate cancer and ladder cancer and has a compacted relationship with them.In this review,we summarized the structure,distri- bution,function of different estrogen receptor subtypes and progress in study on relationship between different estrogen receptor subtypes and prostate or bladder cancer.

Objective To longitudinally analyze the unit costs and technical efficiency of the model of male circumcision in the different kinds of persons .Methods Unit costs were calculated by the person and period using longitudinal data from 3 kinds of persons ,and then technical efficiency and Malmquist indices were measured with an approach to data envelopment analysis . Results Theunit costs for changing the willingness to accept surgery changed dramatically ,decreasing from 7 166 .67 yuan(mean) to 737 .31 yuan ,while the costs for changing the ratio of the surgery increased from 666 .64 yuan (mean) to 744 .58 yuan ,and its technical efficiency was averaging between 0 .95-0 .96 .Conclusion The time series of unit costs for changing the willingness to ac-cept surgery dramatically dropped ,while changing the ratio of the surgery formed a U-shape curve with an inflection point before which unit costs dramatically dropped and another inflection point beyond which unit costs went up .These findings can inform pro-gram managers of the changing unit costs when extending or expanding the program .

The incidence rate of erectile dysfunction (ED) is reportedly as high as 30-90% after radical prostatectomy for prostate cancer, which seriously affects the patients' quality of life. Penile rehabilitation is defined as the use of any drug or device at or after radical prostatectomy to maximize erectile function recovery. A variety of treatment options are available for post-prostatectomy ED patients, including oral phosphodiesterase 5 inhibitors (PDE5I) , intracorporal injections, vacuum erection device, and penile prosthesis. This article presents an overview of the currently used methods for the drug treatment and penile rehabilitation of the ED patients after radical prostatectomy. It seems proper to recommend daily use of a vacuum erection device plus oral PDE5I in the early postoperative period. For those who fail to respond to this therapy, intraurethral alprostadil, intracorporal injections, or a penile prosthesis could be considered.
Alprostadil ; administration & dosage ; Combined Modality Therapy ; Erectile Dysfunction ; etiology ; therapy ; Humans ; Male ; Penile Erection ; Penile Prosthesis ; Phosphodiesterase 5 Inhibitors ; administration & dosage ; Prostatectomy ; adverse effects ; Quality of Life ; Recovery of Function ; Vacuum

Aging ; Humans ; Presbycusis ; genetics

The inheritance of famous old traditional Chinese medicine (TCM) doctors plays an essential role in the fields of TCM research. Qualitative interviews allow for subjectivity and individuality within clinical experience as well as academic ideas of doctors, making it a potential appropriate research method for inheritance of famous old TCM doctors. We summarized current situations of inheritance research on famous old TCM doctors, and then discussed the feasibility of applying qualitative interviews in inheritance of famous old TCM doctors. By combining our experience in research on inheritance of famous old TCM doctors, we gave some advice on study design, interview implementation, data transcription and analyses , and report writing, providing a reference for further relevant research.
Humans ; Interviews as Topic ; Medicine, Chinese Traditional ; Physicians ; Research Design ; Writing

Objective To investigate the roles of cell apoptosis and the gene expressions of Fas, FasL, bcl-2 and bax in acute rejection of pancreaticoduodenal transplantation and to evaluate the function of duodenum biopsy for early detection of rejection in rats. Methods Wistar and SD rats were divided into two groups: ①Wistar rats that underwent allogenic pancreaticoduodenal transplantation from the organs of SD rats; ②Wistar rats that received homogenic transplantation. The grafts were then harvested on day 3, 5 and 7 after the transplantation, and all graft samples were observed with HE staining and TUNEL was also used to detect apoptotic cells. The expressions of Fas, FasL, bcl-2 and bax were measured by immunochemical method. According to Nakhleh’s score, pathologic features of transplanted pancreas and duodenum were ranged from one to three scores in order. Results The percentage of same or different scores between the pathological scores of pancreas and duodenum in allogenic pancreaticoduodenal transplantation group were 61.1% (11/18) and 38.9% (7/18) respectively, and there were 6 specimens of pancreatic tissue got higher scores with only one higher score for duodenum. There were significant differences of histopathologic rejection scores and apoptotic indices between the two groups, respectively (P