9.Updated treatment of erectile dysfunction after prostatectomy.
Qiang DONG ; De-yi LUO ; Hao ZENG
National Journal of Andrology 2015;21(6):483-488
The incidence rate of erectile dysfunction (ED) is reportedly as high as 30-90% after radical prostatectomy for prostate cancer, which seriously affects the patients' quality of life. Penile rehabilitation is defined as the use of any drug or device at or after radical prostatectomy to maximize erectile function recovery. A variety of treatment options are available for post-prostatectomy ED patients, including oral phosphodiesterase 5 inhibitors (PDE5I) , intracorporal injections, vacuum erection device, and penile prosthesis. This article presents an overview of the currently used methods for the drug treatment and penile rehabilitation of the ED patients after radical prostatectomy. It seems proper to recommend daily use of a vacuum erection device plus oral PDE5I in the early postoperative period. For those who fail to respond to this therapy, intraurethral alprostadil, intracorporal injections, or a penile prosthesis could be considered.
Alprostadil
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administration & dosage
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Combined Modality Therapy
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Erectile Dysfunction
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etiology
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therapy
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Humans
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Male
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Penile Erection
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Penile Prosthesis
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Phosphodiesterase 5 Inhibitors
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administration & dosage
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Prostatectomy
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adverse effects
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Quality of Life
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Recovery of Function
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Vacuum
10.Changes of SCD_(14)、TNF-?、E-SLT and IL-10 level in the process of infection
Yong YANG ; Kaiyuan LUO ; De SHI
Chinese Journal of General Surgery 2000;0(11):-
Objective To investigate the changes of SCD 14, TNF-?, E-SLT and IL-10 level in the process of infection.Methods Serum E-SLT, IL-10, SCD 14 and TNF-? level was measured in 37 patients of abdominal trauma, and in model rabbits with endotoxemia.Results Serum level of SCD 14,TNF-?,E-SLT and IL-10 on the 1st to 3rd day post-op increased significantly in patients suffering from post-op infection 〔(1.61?0.47)??g/ml, (28.63?8.29)?pg/ml,(153.6?48.9)?ng/ml and (38.21?10.87)?pg/ml, compared with control, all P