1.Hyperbaric oxygenation and penis erectile dysfunction.
Journal of Biomedical Engineering 2014;31(2):477-480
Relaxation and contraction factors influencing penile erection are produced and released by the central and peripheral nerves as well as intracavernosal sinus gap and vascular endothelial cells. Aging, diabetes, cardiovascular disease and spinal cord injury can influence these factors. Further researches of hyperbaric oxygenation (HBO) on the erectile dysfunction (ED) can provide some theoretical evidences for the clinical treatment of ED.
Erectile Dysfunction
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therapy
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Humans
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Hyperbaric Oxygenation
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Male
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Penis
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physiopathology
2.Clinical thinkings on the diagnosis and treatment of peritoneal effusion
Chinese Journal of Practical Internal Medicine 2000;0(12):-
There is a small amount of liquid in healthy people's abdomen,but excessive liquid in abdomen has been called peritoneal effusion or ascites.Ascites is a common clinical sign.Though many causes can lead to ascites,cirrhosis,malignancy and tuberculosis are more common.According to different causes and physical and chemical properties,ascites can be divided into extravasate and transudate.It is important to distinguish between benign and malignant ascites,but sometimes the differential diagnosis is difficult.In this paper,the characteristics of the ascites,the procedure of diagnosis and treatment are discussed.
3.Clinical application of 3-D surface reconstruction by multislice spiral CT in the diagnosis of impacted teeth in maxilla
Journal of Practical Stomatology 2001;0(01):-
Objective:To evaluate the feasibility of the 3-D surface reconstruction by multislice spiral CT(MSCT) technique in the diagnosis of impacted teeth in maxilla.Methods:Eighty two cases with impacted teeth in maxilla were examined with volumetric CT scan using MSCT,the dental reconstruction images were obtained with multiplanar reformation technique and 3D-reconstruction technique.Results:Dental surface 3D-reconstruction image could display the shape,location and eruption orientation of the impacted teeth clearly.Conclusion:3-D surface reconstruction by MSCT can provide valuable diagnostic and anatomic information of the impacted teeth in maxilla.
4.A primary study on the antimutagenesis activity of fruit-vegetable beverage(carrot juice)
Cancer Research and Clinic 1997;0(03):-
Objective To detect the antimutagenesis of carrot juice and to provide necessary data for the development of fruit-vegetable beverage. Methods Revised rat salmonella mutagenicity test was used, strains had been cultured for 48 hours at a constant temperature of 37 ℃. We counted the anaphysis strains produced in the paper circle, and judged whether there was a antimutagenesis effect according to the difference of the anaphysis strain number between the samples and the dissolvent controls. We also judged the mutagensis effect of the samples based on the anaphysis strains outside the paper circle. Results TA98-TA100 strains were all inside the normal scope, mutagenesis effect of all samples had not been observed. Conclusion Under our laboratory conditions, the inhibition rate of sample Ⅰ,Ⅳ on the induction of N-methy1-N/-nitroso-N-nitrosoguanidine(MNNG) to TA100-S9 and of sample Ⅱ, Ⅲ on the induction of aflatoxin B1( AFB1) to TA+S9 was high, and dose-response effect was obvious, also the inhibition effect of both sample Ⅰ,Ⅱ on the induction of AFB1 and that of sample Ⅰ on the Benzo(a)pyrene (BAP) to TA100+S9 was relatively high, but there was no dose-response effect exist.
5.Study on PBR expression in telencephalon of schistosomiasis mice with liver fibrosis
Chinese Journal of Schistosomiasis Control 1989;0(02):-
Objective To explore the change of peripheral benzodiazepine receptors (PBR) expression in the telencephalon of mice with schistosomiasis. Methods The changes of PBR mRNA in the telencephalon of schistosomiasis mice were observed by the real-time FQ-PCR method. The results were judged with circle number of times (C_T) when the level of amplification exponent achieved detecting liminal value. Results Comparing the experiment group (n=10) with the healthy control (n=10) at the 8th、12th、20th week, the changes of C_T were significant(P
6.The experiences of reconstruction for the digestive tract after total gastrectomy by interposition jejunum
Chongqing Medicine 2001;(1):29,32-
Objective To investigate ideal procedure of reconstruction for the digestive tract after total gastrectomy.Methods:After total gastrectomy,the 25 centimeters length jejunum with vessel pedicle was dissociated and was inosculated between esophagus distal and duodenum proximal end.This procedure is simple and meet the physiological need.Results:28 cases of patients were curved recently without complications and death.All patients wre followed-up long term survey that they had no intestinal symptoms,reverse esophagitis and nutritional deficiency.Their body weights were increased significantly and could take part in labor.Conclusion:This procedure is the ideal reconstruction operation for the digestive tract after total gastrectomy.
7.Cooperative learning in European medical education
Chinese Journal of Medical Education Research 2006;0(12):-
To analyze and summarize the connotation,elements,procedure and efficacy of cooperative learning in European medical education and provide reference to innovate our medical education.
8.Comparison of acute ischaemic stroke adult patients with atrial fibrillation to without atrial fibrillation in the effect on renal dysfunction
The Journal of Practical Medicine 2017;33(7):1040-1043
Objective To find out whether inpatients with acute ischaemic stroke and atrial fibrillation (AF) have higher rate of renal dysfunction than without AF,and analyze risk factors associated with renal dysfunction.Method 374 patients with acute ischaemic stroke and AF were enrolled,which cases have complete data.500 patients were randomly selected as the non-AF group.To compare the prevalence of renal dysfunction [eGFR < 60 mL/(min· 1.73 m2)] of two groups.Non-conditional Logistic regression analysis was used to detemmine the factors associated with renal dysfunction.Results 374 patients in AF group,114 (30.5%) were renal dysfunction;500 patients in non-AF group,75 (15%) were renal dysfunction (P =0.000,OR =2.485).The eGFR of AF and non-AF group was (77.75 ± 39.89) mL/(min· 1.73 m2) and (96.93±39.14) mL/(min · 1.73 m2).In Logis tic regression analysis,heart dysfunction (OR =2.057),hypertension (OR =1.826),diabetes (OR =1.897),hypevuricemia (OR =3.161) were found to be associated with renal dysfunction.Conclusions Adult patients with acute ischaemic stroke and AF have a higher rate of renal dysfunction than acute ischaemic stroke without AF.Heart dysfunction,hypertension,diabetes,hyperuricemia were factors associated with renal dysfunction.
9.Optimize Clinic Management with Clinical Appointment
Journal of Zhejiang Chinese Medical University 2015;(6):490-493
Objective] To study the impact of outpatient appointment supposed on the management of outpatient department and whole hospital. [Methods] Survey and research the average outpatient registration volume, patients' registration waiting time and the patients' satisfaction monthly during May 2011 to May 2014 when outpatient appointment was applied, and analyze the impact of outpatient appointment supposed on the management of outpatient department and whole hospital by comparing the results 3 years ago(during April 2008 to April 2011) when outpatient appointment was not applied. [Results] The number of patients with an appointment was on the rise, the total number of outpatients increased with the increase of outpatient appointment, and patients' registration waiting time was significantly shortened with higher satisfaction. The difference had statistical significance( P<0.05). [Conclusion] By outpatient appointment services, outpatient management has been optimized, with the increase of outpatients; the hospital benefits grow, and meanwhile the patients' satisfaction is improved.
10.Crosstalk of autophagy and ROS in multiple myeloma cells stimulated with doxorubicin
Chinese Journal of Pathophysiology 2016;32(4):665-670
AIM:To investigate the relationship of autophagy and reactive oxygen species ( ROS) in multiple myeloma cell line RPMI-8226 stimulated with doxorubicin.METHODS:The RPMI-8226 cells were stimulated with doxo-rubicin at different doses, and untreated cells were used as control.The protein expression of beclin 1 and LC3 was detec-ted by Western blot.ROS production was analyzed by DCFH-DA fluorescence staining.After treated with or without 3-methyladenine (3-MA), the ROS production and apoptosis in RPMI-8226 cells were determined by DCFH-DA and flow cy-tometry, respectively.After treated with or without antioxidants tempol and N-acetyl-L-cysteine ( NAC) , the expression of beclin 1 and LC3 in RPMI-8226 cells was determined by Western blot.RESULTS:The protein levels of beclin 1 and LC3Ⅱ/LC3Ⅰwere increased in the RPMI-8226 cells stimulated with doxorubicin compared with untreated group.The ROS production was increased in the RPMI-8226 cells stimulated with 2 mg/L doxorubicin compared with untreated group.After treated with 3-MA, the ROS production and apoptosis in the RPMI-8226 cells stimulated with doxorubicin were increased compared with doxorubicin group.After treated with antioxidant NAC or tempol, the expression of beclin 1 and LC3 II/I in the RPMI-8226 cells stimulated with doxorubicin was decreased compared with doxorubicin group.CONCLUSION:The autophagy and ROS levels are increased in RPMI-8226 cells stimulated with doxorubicin.Inhibition of autophagy increases the ROS production and apoptosis of RPMI-8226 cells stimulated with doxorubicin.Inhibition of ROS production reduces doxorubicin-induced autophagy in multiple myeloma cells.