1.Correlative analysis in emotional distress and coping style during acute stage in patients following a-cute traumatic injury
Chinese Journal of Practical Nursing 2009;25(17):42-44
Objective To investigate the emotional distress and coping style during acute stage in patients following acute traumatic injury, and the relationship in different coping patterns and emotional distress. Methods A total of 118 patients with acute traumatic injury were included in our investigation.Emotional distress was assessed with the Hospital Anxiety and Depression scale. Coping style was measured with the Medical Modes Questionnaire. Descriptive analysis, independent samples t test and multiple linear regression analysis were used. Results Emotional distress occurred in 50.00% of the patients with acute traumatic injury,22.40% patients only presented anxiety, 17.30% patients only presented depression, and 10.20% patients presented both anxiety and depression. Yielding and avoidance coping styles were more frequently used in patients with depression. Conclusions Incidence of emotional distress was highly fre-quently, many factors were associated with patients" affection reaction.
2.Yin-yang Chi-pulse diagnosis and its application
International Journal of Traditional Chinese Medicine 2012;34(5):426-428
Chi-pulse diagnosis is a kind of pulse diagnosis by only feeling Chi part of pulse.This method focuses on inborn Yin-yang,fire-water,and growth and decline of kidney essence,emphasizes on the physiological and pathological changes of eight extra meridians and extra viscera,clarifies and expands the content of narrow sense of yin-yang method.Chi-pulse diagnosis is prone to guided by the spot pulse feeling,do not limited by regular pulse name,and has special pulse diagnose experience and fixed knowledge of formula prescription.
3.Development and management of talents with high potentials
Chinese Journal of Hospital Administration 2012;28(9):702-704
The paper described the nature of talents with high potentials as a source of leaders,highlighting their features of uncertainty,relativity and opportunity.Authors presented their insights and experiences in developing such talents into leaders of the hospital,and hold that nurturing of such talents calls for systematic emphasis,competence models to identify them,building an environment for them to stand out,and building of an appraisal and incentive mechanism that is scientific and efficient.
4.Tumor cell invasion and angiogenesis in the mechanism of liver metastasis in gastric cancer
International Journal of Surgery 2012;39(9):622-625
The most common site of hematogenous metastasis of gastric is liver,its prognosis is bad.It is a common cause of death in patients with gastric cancer.In the past few years,along with the development of molecular biology,the mechanism of tumor metastasis has been known gradually.Tumor metastasis is multistep process,the most important condition is cell invading and angiogenesis.Here the author summarize the mechanism of cell invasion and angiogenesis.
5.Cranial defect repair with coralline hydroxyapatite scaffolds in combination with concentrated growth factors in rabbits
Journal of Medical Postgraduates 2017;30(4):376-379
Objective Bone defect repair remains a challenge in regenerative medicine, which has triggered a research upsurge on improving the bone repairing effect using heterogeneous bone combined with growth factors.The aim of this study was to evaluate local bone formation following surgical implantation of coralline hydroxyapatite (CHA), a heterogeneous bone, in combination with the concentrated growth factor (CGF).Methods This randomized prospective study included 24 New Zealand rabbits, which were equally divided into a CHA/CGF+CHA, a CHA/CGF+autograft and a CHA+autograft group.A defect 10 mm in diameter was made in the parietal bone of each animal and filled with CHA/CGF, CHA or autograft.At 6 and12 weeks after the operation, we observed the bone formation by micro-CT and histological examination.Results The bone volume (BV) was significantly higher in the CHA/CGF+CHA than in the CHA+autograft group both at 6 weeks ([39.00±7.61] vs [32.12±6.55] mm3, P<0.05) and at 12 weeks after the operation ([49.75±2.36] vs [39.45±7.02] mm3, P<0.05), and so was the bone mineral density (BMD) ([308.30±29.82] vs [256.85±151.25] mg/mL, P<0.05;[389.00±31.87] vs [302.53±127.05] mg/mL, P<0.05).Histological examination showed that the new bone was distributed throughout the CHA scaffold in the CGF/CHA group at 6 weeks, and the new bone was observed only in the periphery region of the CHA scaffold in the CHA group.The bone defects in the CGF/CHA group were fully repaired at 12 weeks, while those in the CHA group were partly repaired with bone and fibrous tissue in the central region of the defects.Conclusion Combination of CHA with CGF could effectively enhance bone healing.CHA/CGF compound artificial bone is an ideal substitute in bone transplantation.
6.Mechanisms of chronic injury in a model of heart allograft chronic rejection
Chinese Journal of Immunology 2001;0(07):-
Objective:To study the mechanisms of chronic injury in heart allograft with chronic rejection.Methods:A model of cardiac chronic rejection in the rat based on tolerance induced through donor specific blood transfusions was used.The subpopulation and the distribution of infiltrating cells and the expression of adhesion molecule and growth factors were studied by immunohistochemistry and Northern blot analysis in the chronic rejection model.Results:Infiltrating cells were predominantly T lymphocytes and macrophages,mostly evident in the interstitial,subendocardial and perivascular areas.Allografts were demonstrated significantly elevated number of CD45+,CD4+,CD8+,TCR+,CD45RB+ cells,macrophages(ED_1) and NK cells at both 3 and 6 months compared with normal rat hearts and isografts at 3 months.Damaged areas also were observed expression of the adhesion molecules ICAM-1,LFA-1,basic fibroblast growth factor (bFGF) and transforming growth factor(TGF-?1).Northern blot analysis of total RNA,showed 5 to 6 fold upregulation of TGF-?1 mRNA in the chronic rejection model compared with normal rat hearts.Conclusion:These results suggest that T lymphocytes and macrophages play a central role in the development on chronic rejection and the increased expression of ICAM-1,LFA-1,bFGF and TGF-?1 in this model supports the involvement of these adhesion molecules and growth factors in the development of cardiac allograft vasculopaphy.
7.Noninfectious pulmonary complications following hematopoietic stem cell transplantation
Chinese Journal of Tissue Engineering Research 2015;(10):1630-1634
BACKGROUND:Hematopoietic stem cel transplantation is a promising treatment for a variety of malignant and nonmalignant disorders. But noninfectious pulmonary complications folowing hematopoietic stem cel transplantation are a major cause of morbidity and mortality in these patients. And the diagnosis and treatment are difficult. OBJECTIVE: To review the noninfectious pulmonary complications after hematopoietic stem cel transplantation in terms of onset time, risk factors, clinical manifestations, characteristics of the high-resolution CT, histopathological measurement, related genes and treatment options. METHODS: A computer-based search of VIP, PubMed and Sciencedirect databases was performed for articles related to noninfectious pulmonary compli cations after hematopoietic stem cel transplantation published from January 2005 to October 2014. The key words were “HSCT, pulmonary complications, non-infectious, pirfenidone” in Chinese and English in the title and abstract. Finaly, 31 articles were included in result analysis. RESULTS AND CONCLUSION: The incidence of noninfectious pulmonary complications after hematopoietic stem cel transplantation has become more and more, with atypical clinical manifestations and limited diagnosis and treatments. According to the different clinical onset time, diagnostic criteria, clinical manifestations and the appropriate laboratory tests, clinicians can make early diagnosis and early intervention. Especialy, the usage of high-resolution chest CT and bronchofiberscope for bronchoalveolar lavage as wel as the timely drug administration can improve the survival rate of patients with noninfectious pulmonary complications after hematopoietic stem cel transplantation.
8.Extended resection for pancreatic carcinoma.
Chinese Journal of Practical Surgery 2001;21(1):54-56
ObjectiveIn order to enhance the curative resectability rate of pancreatic carcinoma. MethodsSixteen consecutive patients received an extended resection, which is referred to systemic dissection of regional lymph nodes and combined resection of the diseased PV/SMV based on traditional Whipple operation or the distal pancreatectomy. ResultsMean operation time was 8.5 hours. Mean intraoperative blood infusion was 1250mL. The procedure was considered curative in 11 (68.8 % ) and palliative in the other five. Postoperative complications occurred in 7 (43.8% ). Perioperative death occurred in one patient(6.25% ). Median length of hospital stay was 35 days. In nine patients undergoing curative resection,two cases survived for 1/2~1 year, six patients survived for 1~2 year and another patient has survived for more than 32 months without evidence of recurrence. ConclusionExtended resection for pancreatic cancer is technically feasible and two- third of pancreatic carcinoma invading PV/SMV alone can be expected to obtain curative resecetion.
9.Determination of Baicalin in Xiaochaihu Tablet by HPLC
Traditional Chinese Drug Research & Clinical Pharmacology 1993;0(04):-
Objective: To establish a HPLC method for determination of Baicalin in Xiaochaihu Tablet. Method: HPLC was used with C18 column, CH3OH - H2O - H3 PO4 (42: 58: 0. 2) as mobile phase and detection wavelength at 280nm. Results: Baicalin showed a good linear relationship at the range of 0. 2 - 1. 0ug. The average recovery was 98. 01% and RSD was 1. 07 %. Conclusion: This method is simple and accurate, and can be used for the quality conltrol of Xiaochaihu Tablets.
10.Situation and Development of Technology Literacy of Physical Therapist in China
Chinese Journal of Rehabilitation Theory and Practice 2009;15(2):199-200
The field of rehabilitation medicine physical therapist (PT) training and education has been relatively weak links in China, how to build a rehabilitation therapist team, we constantly explore and get a greater progress. However, most of the time is still confined to empty the contents of most theoretical level, and some basic steps and the specific contents are lacked. How to stabilize therapists team? How to position therapists? It deserves to pay more attentions.