OBJECTIVE To investigate distribution status and drug-resistance of pathogens from infected urinary tract and offer scientific evidence for reasonably clinical usage of antibiotics.METHODS A total of 336 strains of pathogenic bacteria isolated from urinary tract infection from 2003 to 2007 were identified,and antibiotic susceptibility test was performed by K-B methods.RESULTS The total isolating rate of Gram-negative bacilli was 78.3%.And that of Gram-positive cocci was 16.4%.Escherichia coli accounted for 64.9%,ranking the first.Except for 100% sensitive to vancomycin in Gram-positive cocci and 100% sensitive to imipenem in Gram-negative bacilli,all pathogens were resistant to the other antibiotics in different degrees.The detection rate of extensive-spectrum beta-lactamases(ESBLs) producers in E.coli and Klebsiella pneumoniae were 25.7% and 28.0%,respectively.CONCLUSIONS The drug-resistance of pathogenic bacteria from infected urinary tract emergs in Yinshan County.We should adopt effective measurement to prevent and control it.