1.Pulmonary tuberous sclerosis - a case report.
Yap Piang KIAN ; J SINGH ; R MURUGASU
Singapore medical journal 1979;20(3):402-405
Adult
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Female
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Hemangioma
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complications
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Humans
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Kidney Neoplasms
;
complications
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Lipoma
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complications
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Lung Diseases
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complications
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diagnosis
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Tuberous Sclerosis
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complications
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diagnosis
2.Lymphangiomyomatosis Arising in the Pelvic Cavity: A Case Report.
Hun Soo KIM ; Moon Il PARK ; Kwang Sun SUH
Journal of Korean Medical Science 2005;20(5):904-907
Lymphangioleiomyomatosis (LAM) is a rare disease usually occurring in young women of child-bearing age. It is characterized by a distinctive proliferation of lymphatic smooth muscle cells, especially occurring in the pulmonary parenchyme. The majority of primary LAM occurs in the lung, but there are a few reports of extrapulmonary cases. We report a case of a 21-yr-old female who first complained of low abdominal pain and was referred from a local clinic with the impression of an ovarian cyst. Gynecologic ultrasonography revealed a large posterior pelvic mass with an irregular echogenicity measuring 9.7x4.2 cm in size. Pelviscopy showed a large, thin walled, partly cystic, pelvic mass. The mass was partly removed. Microscopically, the mass was characterized by a haphazard proliferation of smooth muscle cells arranged in fascicular, trabecular, and papillary patterns around a ramifying network of endothelium-lined spaces. The cells were plump or epithelioid with abundant eosinophilic cytoplasm and showed a positive reaction for both alpha-smooth muscle actin and HMB-45 antigen. Surgical and pathological findings were consistent with pelvic retroperitoneal LAM. Despite the numerous treatment attempts, the patient suffered from intractable chylous ascites and developed pulmonary LAM and died due to severe respiratory distress.
Abdominal Pain/diagnosis/etiology
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Adult
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Diagnosis, Differential
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Female
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Humans
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Lung Neoplasms/complications/*diagnosis
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Lymphangioleiomyomatosis/complications/*diagnosis
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Pelvic Neoplasms/complications/*diagnosis
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Rare Diseases/complications/diagnosis
3.Lung squamous cell carcinoma combined with tuberculous pleurisy.
Yi ZHANG ; Shu-Yang YAO ; Yuan-Bo LI ; Jian ZHANG
Chinese Medical Journal 2012;125(20):3755-3756
Carcinoma, Squamous Cell
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complications
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diagnosis
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surgery
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Humans
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Lung Neoplasms
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complications
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diagnosis
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surgery
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Male
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Middle Aged
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Tuberculosis, Pleural
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complications
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diagnosis
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surgery
5.Analysis of the clinical diagnosis of asbestosis complicated with malignant mesothelioma.
Yan LIANG ; Yan WANG ; Songquan ZHANG ; Juan LIU ; Yanxia CHEN ; E-mail: CHENYXQD@126.COM.
Chinese Journal of Industrial Hygiene and Occupational Diseases 2015;33(5):380-382
OBJECTIVETo discuss the clinical characteristics, diagnosis and treatment of the clinical characteristics and prognosis of asbestosis complicated with malignant mesothelioma patients.
METHODSIn 3 cases of asbestosis complicated with malignant mesothelioma were retrospectively analyzed.
RESULTSIn the 3 patients, 2 cases of pleural mesothelioma, with chest tightness, chest and back pain as initial symptom; 1 case of peritoneal mesothelioma, with abdominal distention, abdominal pain, dysuria as initial symptom. One case of the pleural mesothelioma misdiagnosed as tuberculous pleurisy. 3 patients were in CT or B ultrasound guided biopsy pathology confirmed to be malignant mesothelioma. 2 patients received systemic chemotherapy, another received symptomatic and supportive treatment. Up till now, 3 patients have died.
CONCLUSIONThe disease is a high degree of malignant, the early clinical manifestations are not specific, easily missed diagnosis and misdiagnosis. The treatment effect is not ideal, the prognosis is poor. Biopsy is a reliable method for diagnosis of MM.
Abdominal Pain ; Asbestosis ; complications ; diagnosis ; Back Pain ; Biopsy ; Diagnostic Errors ; Humans ; Lung Neoplasms ; complications ; diagnosis ; Mesothelioma ; complications ; diagnosis ; Peritoneal Neoplasms ; Pleural Neoplasms ; Prognosis ; Retrospective Studies ; Tuberculosis, Pleural
6.Application of percutaneous needle aspiration biopsy by the simulator guided to the diagnosis for pulmonary focus in coal miners' pneumoconiosis.
Si-hai LIU ; Cheng-dong QI ; Wen-shou XU ; Rui-xia ZHU ; Qin YAN ; Wen FENG ; Rong-xia SUN ; Yan-fang ZHANG ; Xiao-fu WU ; Zheng-chuan FU
Chinese Journal of Industrial Hygiene and Occupational Diseases 2004;22(1):72-73
Aged
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Biopsy, Needle
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methods
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Coal Mining
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Humans
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Lung
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pathology
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Lung Neoplasms
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complications
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diagnosis
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Middle Aged
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Pneumoconiosis
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complications
7.Pulmonary metastases 12 years after a mastectomy for borderline phyllodes tumor.
Xiao-Meng NIE ; Yang WANG ; Xiao-Peng YAO
Chinese Medical Journal 2011;124(24):4376-4377
Phyllodes tumor is a rare breast tumor. A 45-year-old woman who underwent left mastectomy 12 years ago was found to have infiltrates in both lungs in a health examination. Combining histological examinations of the lung and breast samples, the diagnosis of borderline phyllodes tumor metastases to the lung was made. It is the longest interval to our knowledge that the metastases occurred 12 years after primary phyllodes tumor.
Breast Neoplasms
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complications
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surgery
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Female
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Humans
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Lung Neoplasms
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secondary
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Middle Aged
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Phyllodes Tumor
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diagnosis
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secondary
8.Endobronchial Metastases after Radical Resection of a Primary Lung Cancer.
Xue-Ming HE ; Guo-Xing CHEN ; Zhi-Jun LIU ; Yong-Yong WU ; Zhong-Liang HE
Chinese Medical Journal 2017;130(3):372-373
Bronchial Neoplasms
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diagnosis
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secondary
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surgery
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Humans
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Lung Neoplasms
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complications
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surgery
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Male
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Middle Aged
9.Analysis of Small Cell Lung Cancer with Paraneoplastic Limbic Encephalitis.
Chinese Journal of Lung Cancer 2019;22(3):132-136
BACKGROUND:
The aim of this study was to investigate the clinical features of paraneoplastic limbic encephalitis (PLE) with small cell lung cancer (SCLC) and improve clinical diagnosis and treatment.
METHODS:
The clinical data of 15 patients with SCLC combined with PLE from January 1980 to May 2017 were collected from Beijing Union Hospital. Their symptoms and laboratory data were analyzed and the prognosis of the patients was followed.
RESULTS:
PLE is a rare disease, the incidence rate in SCLC is about 0.842%. The data may be underestimated because of misdiagnose or missed diagnosis; High incidence crowd of the disease is the middle-aged male smoker, the tumor-node-metastasis (TNM) stages of them are later than others; Typical neurological symptoms include varying degrees of short-term memory loss, seizures and varying degrees of mental disorders; neurological symptoms usually occur before the onset of cancer or respiratory symptoms appear, an average of about 2 months be taken from onset to diagnosis; Serum antibody (anti-Hu, GABA-R-Ab), cerebrospinal fluid, head magnetic resonance imaging (MRI) and electroencephalogram (EEG) of the patients has abnormalities; Videography, especially computed tomography (CT) is a good means of screening the primary tumor, pathology diagnosis mainly rely on bronchoscopy; The treatment of primary tumors can be more effective in alleviating the nervous system symptoms than immunotherapy.
CONCLUSIONS
Paraneoplastic limbic encephalitis is a rare paraneoplastic syndrome in nervous system caused by malignant neoplasms often characterized by facial neurological symptoms. The disease are usually associated with lung cancer (especially SCLC). Its nervous system symptoms occur earlier than the tumor diagnosis. Early diagnosis and treatment for primary tumors will increase the benefit.
Adult
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Aged
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Female
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Follow-Up Studies
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Humans
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Limbic Encephalitis
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complications
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Lung Neoplasms
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complications
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diagnosis
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therapy
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Male
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Middle Aged
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Prognosis
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Retrospective Studies
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Small Cell Lung Carcinoma
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complications
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diagnosis
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therapy
10.A Case of Lambert-Eaton Myasthenic Syndrome Associated with Atypical Bronchopulmonary Carcinoid Tumor.
Jae Hyeok LEE ; Jin Hong SHIN ; Dae Seong KIM ; Dae Soo JUNG ; Kyu Hyun PARK ; Min Ki LEE ; Jee Yeon KIM
Journal of Korean Medical Science 2004;19(5):753-755
The Lambert-Eaton myasthenic syndrome (LEMS) is typically recognized as a paraneoplastic syndrome associated with a small cell lung carcinoma (SCLC), whereas LEMS with other neuroendocrine lung tumors, including carcinoids or large cell lung carcinoma, are highly unusual. Here, we report a rare case of LEMS with atypical bronchopulmonary carcinoid tumor: A 65-yr-old man presented with progressive leg weakness and a diagnosis of LEMS was made by serial repetitive nerve stimulation test. Chest CT revealed a lung nodule with enlargement of paratracheal lymph nodes, and surgically resected lesion showed pathological features of atypical carcinoid tumor. We concluded that LEMS could be associated with rare pulmonary neuroendocrine tumor other than SCLC, which necessitates pathologic confirmation followed by aggressive treatment for optimal management in these rare cases.
Aged
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Carcinoid Tumor/*complications/pathology/surgery
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Electromyography
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Humans
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Lambert-Eaton Myasthenic Syndrome/*complications/diagnosis
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Lung Neoplasms/*complications/pathology/surgery
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Male