Objective To evaluate the efficacy and safety of modified technique of ureteral stent placement during transurethral resection of bladder tumor.Methods Seventeen patients with muscle invasive bladder cancer invading the ureteral orifice from March 2014 to June 2016 in Beijing Friendship Hospital were randomly divided into two groups.In the modified technique group (group A,n =10),tumor was resected until the ureteral orifice was exposed.Then,a guide wire was placed through the tunnel of Electrode loop and the ureteral stent was placed along the guide wire.In control group (group B,7 cases),after ureteral orifice exposed,the guide wire and ureteral stent was placed with cystoscopy.The demographic,oncological baseline and operative factors were evaluated between two groups.Results There was no difference in tumor grade and maximum diameter between two groups (P ＞ 0.05).The operation time in group A was significantly shorter than that in group B [(39.5 ± 14.8)min vs (59.3 ± 16.2) min,P =0.020],and the intraoperative vision clarity score was better in group A as well [(7.7 ± 1.3) vs (5.9± 1.2),P =0.010].There was no statistical difference between the two groups in the complication.Conclusions The modified technique can improve the efficiency of ureteral stent placement during transurethral resection of bladder tumor without any risk enhancement.

Objective: To determine the rationality of prescription of Xiaoyu tablets. Methods: The effects of Xiaoyu tablets and its single constituents on endothelin-1(ET-1) and nitric oxide(NO) in atherosclerotic rabbits were observed. Results: Xiaoyu tablets showed stronger actions than its single constituents (extract of radix salviae miltiorrhizae or fructus crataegi) in decreasing the contents of ET-1 in plasma and atherosclerotic vessel wall and increasing the contents of NO in serum and atherosclerotic vessel wall. Conclusion: There was the obvious synergism on reduction of ET-1 and elevation of NO in atheroscleerotic rabbits when both extracts of the Chinese herbal medicines were simultaneously used.

Object To determine the rationality of prescription of XIAOYU TABLETS. (Tablet for the elimination of blood stasis). Methods The effects of XIAOYU TABLETS and its individual constituents on endothelin 1 and nitric oxide in atherosclerotic rabbits were observed and compared. Results XIAOYU TABLETS showed stronger actions than its individual constituents (extract of Radix Salviae Miltiorrhizae or Fructus Crataegi) in decreasing the contents of endothelin 1 in plasma and atherosclerotic vessel wall and increasing the contents of nitric oxide in serum and atherosclerotic vessel wall. Conclusion The combine use of Radix Salviae Miltiorrhizae and Fructus Crataegi extracts showed an obvious synergistic effect on reduction of endothelin 1 and elevation of nitric oxide in atherosclerotic rabbits.

Objective To investigate the clinical characteristics and strategy of prophylaxis and treatment of rabies.Methods Two recipients and their donors with rabies were reviewed to confirm the transmission through kidney transplantation.Saliva,urine,and sputum samples from recipients were collected for the detection of rabies virus by reverse transcription PCR (RT-PCR).Results The donor was a 6-year old boy,died of viral encephalitis of unknown cause.His kidneys and corneas were donated for transplantation.Two recipients who received the donor kidneys had neurological symptoms associated with rabies successively.Both of the two recipients died 44 days and 34 days after onset of post-transplant symptoms.Saliva,urine,and sputum samples were positive for rabies virus nucleic acid.The epidemiological investigation revealed that the boy had a history of close contact with his dog.The parents denied the history of animal bites or rabies prophylaxis.Conclusion The rabies virus can be transmitted through organ transplantation.Incubation period of rabies transmitted from donor is shorter than general population and the mortality rate is up to 100％ after onset of symptoms.So,both coordinators and doctors should deeply understand the rabies.The evaluation and supervision of donor derived diseases should be strengthened.The donors should not be donated whenever the rabies is not completely excluded,especially those died of encephalitis of unknown cause.Furthermore,post-exposure prophylaxis of rabies should be administered as soon as possible before onset of symptoms after transplant from a donor with rabies.

In the present study we explored the different patterns of volumetric atrophy in hippocampal subregions of patients with left and right mesial temporal lobe epilepsy with hippocampal sclerosis (TLE-HS). Meanwhile, the memory impairment patterns in Chinese-speaking TLE-HS patients and potential influencing factors were also determined. TLE-HS patients (21 left and 17 right) and 21 healthy controls were recruited to complete T2-weighted imaging and verbal/nonverbal memory assessment. The results showed that both left and right TLE-HS patients had overall reduced hippocampal subregion volumes on the sclerotic side, and cornu ammonis sectors (CA1) exhibited maximum atrophy. The verbal memory of left TLE-HS patients was significantly impaired (P < 0.001) and was not associated with the volumes of the left hippocampal subregions. Verbal or nonverbal memory impairment was not found in the patients with right TLE-HS. These results suggested that the atrophy of hippocampal subregion volumes cannot account for the verbal memory impairment, which might be related to the functional network.
Adult ; Asian Continental Ancestry Group ; Atrophy ; pathology ; Epilepsy, Temporal Lobe ; complications ; pathology ; Female ; Functional Laterality ; Hippocampus ; pathology ; Humans ; Male ; Memory Disorders ; etiology ; pathology ; Sclerosis ; pathology ; Young Adult