1.comparative study of non-invasive fibrosis serological testing and liver biopsy diagnosis of liver
Lingdi WANG ; Ludan WU ; Weilin MAO
China Modern Doctor 2014;(24):90-92
Objective To compare the serological non-invasive liver fibrosis tests and pathological examination in the clinical diagnosis of chronic hepatitis B. Methods Selected 97 patients with chronic hepatitis B in our hospital as the research object and tested non-invasive liver fibrosis tests and liver biopsy pathological examination.Compare the test results of two kinds. Results The serum noninvasive hepatic fibrosis index(PⅢP,Ⅳ-C,HA,LN)showed good positive correlation with pathological stage. The correlation coefficient suggested that with the aggravation of hepatic fibrosis,liv-er fibrosis indexes tended to rise gradually,and the indicators differences were statistically significant (P<0.05). Con-clusion Liver biopsy in patients with chronic hepatitis B diagnosis detection is the "gold standard" with greater injury. Serological non-invasive liver fibrosis tests has high diagnostic value,can reduce the number of puncture biopsy.
2.Research progress of dental self-healing microcapsule materials
YAO Shuo ; ZHANG Xiaoran ; QIN Ludan ; WU Junling
STOMATOLOGY 2023;43(2):166-169
The self-healing microcapsule material is one of the smart materials that can self-identify and self-heal microcracks. Adding microcapsules to dental resin composites can resist generation of microcracks and prolong service life of resin restorations. In this literature, the overview of self-healing microcapsule materials, the combined application of self-healing microcapsule materials and other modified materials, the silanization treatment of dental self-healing microcapsules, the dynamic mechanics, fatigue and aging studies on self-healing dental resins were comprehensively presented and reviewed. In addition, prospects of dental self-healing microcapsule materials were also discussed.
3.Relationship between environmental tobacco smoke and lung cancer risk among nonsmokers in China: A meta-analysis.
Xin FU ; Tienan FENG ; Minfang WU ; Ludan ZHANG ; Chenghua JIANG ; Email: JCH@TONGJI.EDU.CN.
Chinese Journal of Preventive Medicine 2015;49(7):644-648
OBJECTIVETo investigate the relationship between the environmental tobacco smoke (ETS) and lung cancer by Meta-analysis.
METHODSWe used "lung cancer/lung neoplasm", "non-smoking/non-smoker", "China/Chinese", "case-control/case control", "risk factor", "environmental tobacco smoke/passive smoking" as key words, to search papers in databases including Chinese BioMedical Literature (CBM), China National Knowledge Internet (CNKI), Wanfang, Vip Citation Databases (VIP), PubMed and Web of Science databases, and collected the case-control studies on ETS and lung cancer among Chinese non-smokers from January 1999 to December 2013. A total of 129 research papers were collected. RevMan 5.2 software was used to calculate combined odds radio (OR) and 95% CI.
RESULTSQualified 18 literatures were included, total cases 6 145 and controls 8 132. Consolidated results showed that ETS exposure could increase the risk of lung cancer, combined OR (95% CI) = 1.52 (1.42-1.64). Stratified analysis showed that ETS exposure was found to be significantly associated with an increasing risk of the lung cancer on non-smoking women and men, and combined OR (95% CI) were 1.58 (1.42-1.75) and 1.34 (1.08-1.65), respectively; the ETS exposure from family or the working environment could increase the risk of lung cancer, and combined OR (95% CI) were 1.48 (1.20-1.82) and 1.38 (1.13-1.69) respectively; childhood exposure and adult exposure were no significant statistical significance, and combined OR (95% CI) were 1.37 (0.98-1.91), and 1.34 (0.97-1.85) respectively.
CONCLUSIONEnvironmental tobacco smoke exposure was a significant risk factor of lung cancer among non-smokers in China.
Adult ; Case-Control Studies ; China ; Female ; Humans ; Lung Neoplasms ; Male ; Risk Factors ; Tobacco Smoke Pollution