2.Biomechanical study of single - level anterior cervical intervertebral decompression and fusion with plating uniplate and orion
Feng ZHANG ; Jianhua LU ; Jian ZHAO
Orthopedic Journal of China 2006;0(19):-
0.05).[Conclusion]The stability of the single - level anterior cervical intervertebral decompression and fusion with plating Uniplate is satisfactory.Uniplate is valuable in clinic,furthermore,it is relatively simple to operate.
3.The role of apoptosis in pancreatic cancer therapy
Xiangxuan ZHAO ; Feng WEN ; Zaiming LU
Practical Oncology Journal 2016;30(4):375-379
Pancreatic adenocarcinoma ( PAC) is still a refractory human digest malignancies due to multi-faceted causes ,late diagnosis and insensitive to traditional chemo -and radio-therapy .Resistance to apoptosis could be one of the most relevant mechanisms for PAC to escape any non -surgical therapy .This review aims to clear up the main deregulated apoptosis signal pathways over the years and to find out the abnormal molecule tar -get(s),and therefore,provide novel concepts for PAC molecular targeting therapy .
4.A giant solitary fibrous tumor of the pleura.
Lu-feng ZHAO ; Ying CHAI ; Li-jian HUANG
Chinese Medical Journal 2013;126(15):2999-2999
5.The clinical characteristics and coagulation parameters of the infants with placental abruption
Lu YANG ; Wenli ZHAO ; Qiuping LI ; Jing XU ; Zhichun FENG
Chongqing Medicine 2013;(28):3350-3352
Objective To analyze the clinical characteristics and coagulation parameters of the infants with placental abruption . Methods Analysis was made on clinical and laboratory indexes of the hospitalized children of the NICU of Bayi Clinical Medical College of South Medical University ,enrolled from August 2012 to January 2013 ,including 60 infants with placental abruption as observation group and 60 infants without placental abruption as the control group .Results From clinical manifestations and lab date ,significant differences were found in gestational age ,polyembryony ,premature rupture of membrane ,birth weight ,intrauterine growth retardation ,motherhood gestational hypertension ,mother gestational diabetes mellitus ,asphyxia ,APTT ,D-dimer on admis-sion between the observation group and control group (P<0 .05) .Conclusion Placental abruption is the result of placental insuffi-ciency ,which may cause coagulation disorder and thus show the pathological state of high condensation in infants .
6.Ultrasound-guided percutaneous lauromacrogol injection therapy for simple hepatic or renal cysts
Jianquan ZHANG ; Jianguo SHENG ; Feng LU ; Lulu ZHAO ; Tian YANG
Chinese Journal of Ultrasonography 2013;(6):505-507
Objective To make a comparative assessment on both the therapeutic effects and side effects between percutaenous lauromacrogol injection therapy(PLIT) and percutaenous ethanol injection therapy(PEIT) for simple hepatic or renal cyst.Methods In group A,55 patients with simple hepatic or renal cysts underwent ultrasound-guided aspiration and successive PLIT.The intra-operative side effects were investigated and the therapeutic effects assessment by using ultrasonography was conducted 3 months after the treatment.In group B,60 patients with simple hepatic or renal cysts had received ultrasound-guided aspiration and PEIT sometime before.The intra-operative side effects and therapeutic effects on the thirdmonth ultrasonography were independently reviewed according to their case records.Results In group A,3 patients(5.5 %) expressed slight discomfort but not pain while receiving lauromacrogol injection.Follow-up ultrasound examination at the end of third month demonstrated the cysts in 43 patients completely regressed,while cysts in rest 12 patients shrank over 50 % in size,showing the overall response rate(ORR) and completely cure rate(CCR) were 100% (55/55) and 78.2% (43/55) for PLIT respectively.In group B,12 patients(20%) suffered from slight to moderate irritating pain or drunk performance.The third-month ultrasound examination disclosed that cysts in 47 patients completely vanished,and cysts in the other 13patients shrank more than a half,indicating the ORR and CCR were 100% (60/60) and 78.3 % (47/60) for PEIT respectively.Conclusions Although their therapeutic efficacy are perfectly similar,PLIT is much more superior to PEIT in term of less and minor side effects.
7.Changes of argiuine vaso-pression in blood and cerebral spinal fluid(CSF)in patients with severe brain injury after treated with mild hypothermia
Hui ZHAO ; Weidong HANG ; Feng LU ; Weiming WANG ;
Chinese Journal of Emergency Medicine 2006;0(09):-
Objective To study the changes of blood arginine vaso-pression(AVP)levels in patients with severe brain injury after treated with mild hypotherima.Methods Seventy-eight patients with severe brain injury were divided into mild hypothermia(33~35℃)group and normothermia group.The blood AVP levels and CSF AVP levels were determined at the third and the seventh day after brain injury.Results The AVP levels in blood and CSF of mild hypothermia group were lower than those of the normothermia group at the third and seventh day after brain injury(P<0.05).According to GOS,prognosis of the mild hypothermia group was better than that of the nonnotbcrmia group(P<0.05).Conclusion The mild hypothermia treatment may have inhibitive effects on the production of blood AVP,CSF AVP,and brain edema.Mild hypothermia is an effective method in the treatment of acute severe brain iniury in reducing the mortality and in increasing the survival rate.
8.The relationship between TGF-?_1 mRNA and acute rejection of small intestinal allografts in rats
Feng ZHAO ; Lihong LU ; Jun SHAO ; Jinlin YIN
Chinese Journal of Current Advances in General Surgery 1999;0(02):-
Objective:To investigate the relationship between TGF-? 1mRNA and acute rejection of small intestinal allografts in rats.Methods:Rats were divided into two groups.Group Ⅰ:Wistar→SD Small intestinal transplantation,Group Ⅱ:Wistar→SD Small intestinal transplantation+CsA.The pathologic changes of allografts at 3 rdday,5 thday,7 thday after operation investigated and the transcription of IL-2,IFN- ?,and TGF-? 1mRNA was detected by semi-quantity RT-PCR.Results:Pathologic change:There was acute rejection at 3 rdday,and became severe at 7 thday in group Ⅰ,and there was only slight rejection at 7 thday in groupⅡ.TIFN-?、IL-2mRNA obviously increased after operation in groupⅠ.But they increased only a little in group Ⅱ.It had statistical significance between the two groups(P
9.Comparison of cerebral glucose metabolism between Alzheimer's disease and dementia with lewy bodies
Tao FENG ; Xingquan ZHAO ; Linlong LU ; Xuan ZHANG ; Yoagjun WANG
Clinical Medicine of China 2009;25(4):348-350
Objective To investigate the feature of cerebral glucose metabolism of Alzheimer's disease (AD)and dementia with lewy bodies (DLB).Methods 28 patients with AD and 25 patients with DLB underwent positron emission tomography (PET)with 18 F-fluorodeoxyglucose (18F-FDG)showing glucose metabolism.The region of interest (ROI)was selected from frontal cortex,temporal cortex,parietal cortex,occipital cortex,cerebellum cortex and corpora striata.The 18 F-FDG metabolism ratios between various cerebral regions and cerebellum cortex were compared as an indicator of regional cerebral glucose metabolic patterns.Results The FDG metabolism ratio of parietal cortex and temporal cortex decreased similarly in AD.The FDG metabolism ratio of frontal cortex,parietal cortex,temporal cortex,occipital cortex,dorsal caudate putamen and caudate nucleus in AD was [(0.861 ± 0.173),(0.625 ± 0.149),(0.598 ± 0.185 ),(0.914 ± 0.214),( 1.030 ± 0.084)and ( 0.997 ± 0.102 )].The FDG metabolism ratio of frontal cortex,parietal cortex,occipital cortex,temporal cortex and corpus striatum decreased similarly in DLB.The FDG metabolism ratio of frontal cortex,parietal cortex,temporal cortex,occipital cortex,dorsal caudate putamen and candate nucleus in DLB was [ (0.538 ±0.147),(0.615 ±0.138),( 0.587 ±0.142),(0.415 ±0.107 ),(0.685 ± 0.094)and (0.547 ± 0.103 )].The FDG metabolism ratio of frontal cortex,occipital cortex and corpus striatum decreased more significantly in DLB than in AD (P<0.01 ).Conclusion There are discrepancies in cerebral glucose metabolism between AD and DLB.These features may be useful in differential diagnosis of these two kinds of dementia.
10.CTLA-4 gene polymorphism and protein expression and apoptosis of peripheral blood lymphocytes from idiopathic nephrotic syndrome children with the pathologic type of mesangial proliferative glomerulonephritis.
Feng-ying WANG ; Si-guang LU ; Tong ZHAO
Chinese Journal of Pediatrics 2007;45(8):633-634
Antigens, CD
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genetics
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metabolism
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Apoptosis
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genetics
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CTLA-4 Antigen
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Child
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Female
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Glomerulonephritis
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genetics
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pathology
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Humans
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Male
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Nephrosis, Lipoid
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genetics
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pathology
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Polymorphism, Genetic