1.Eosinophilic gastroenteritis in children
Chinese Journal of Applied Clinical Pediatrics 2016;31(7):484-486
Eosinophilic gastroenteritis (EGE) is a rare disorder characterized by eosinophilic infiltration of the bowel wall with various gastrointestinal manifestations.The etiology of the disease is not clear.EGE can affect the growth and development in children,and can cause a variety of complications.Through the elaborate discussion to the pathogenesis,clinical manifestations,diagnostic criteria and treatment principles of EGE,can strengthen identification to EGE,and improve the level of diagnosis and treatment.
2.The relationship between metabolic syndrome and nonalcoholic fatty liver disease in non-obese hypertensive patients
Ying LU ; Yanxa HUANG ; Xiaomei LI
Journal of Chinese Physician 2009;11(3):329-331
Objective To investigate the relationship between metabolic syndrome(MS)and nonalcoholic fatty liver disease (NAFLD)in non-obese and non-diabetic hypertensive patients.Method 84 non-obese and non-diabetic hyperlensive patients were divided into 42 hypertensive patients with NAFLD and 42 hypertensive patients without NAFLD by abdominal ultrasonography examination.Body mass index(BMI),blood pressure,fast and OGGT 2 hour plasma glucose,fast and OGGT 2 hour plasma insulin,plasma lipids and aminotransferase were measured in the two groups.Multivariate logistic regression analysis was used to identify the variables independently associated with MS.Result BMI,triglycerides,fast insulin,2 hour insulin,aminotransferase,HOMA-IB and MS prevalence rate in the group with NAFLD were significantly higher than these in the group without NAFLD.Multivariate logistic regression analysis(forward LR)showed NAFLD:were independently associated with MS.Conclusion MS play a role not only in occurrence of NAFLD but also in liver injury.
3.Effect of Shenqi Fuzheng injection on immune function and quality of life in patients with advanced gastric cancer chemotherapy
Beina LU ; Feifang WANG ; Ying HUANG
Chinese Journal of Biochemical Pharmaceutics 2017;37(7):136-137
Objective To study the effect of Shenqi Fuzheng injection on immune function and quality of life in patients with advanced gastric cancer.Methods 100 Patients with advanced gastric cancer treated from July 2014 to April 2017 in our hospital were randomly divided into two groups.The patients in the control group were treated with conventional FOLTOX regimen.The patients in the experimental group received Shenqi Fuzheng injection.The immunological function and quality of life of the two groups were analyzed and analyzed.Results Compared with the control group, the content of CD3+ was significantly improved in the patients treated with Shenqi Fuzheng Injection, the content of CD8+ was effectively decreased and the CD4+ / CD8+ ratio was effectively improved.Shenqi Fuzheng injection can effectively improve the immune function of patients, the difference was statistically significant(P<0.01).The number of patients in the treatment group was 39, and the control group was 26, the difference was statistically significant(x2 =7.43, P<0.01).There were 40 patients with sleep improvement in the treatment group and 25 patients in the control group, the difference was statistically significant(x2 =9.89, P<0.01).Conclusion Applying Shenqi Fuzheng Injection on FOLTOX can effectively improve the immunity of patients and improve the quality of life.Shenqi Fuzheng injection in clinical worthy of promotion.
4.CD_4~+ CD_(28)~(null) T cell numbers of peripheral blood in patients with coronary heart diseases
Li-Juan HUANG ; Ying CUI ; Wen-Ying SUN ; Gui-Qin DU ; Lu-Lu LI ;
Chinese Journal of Laboratory Medicine 2001;0(04):-
Objective To investigate changes in CD_4~+ CD_(28)~(null)T cell numbers of peripheral blood and the expression of perforin in patients with coronary heart disease.Methods Sixty-eight patients with acute coronary syndromes,56 with stable angina and 65 healthy subjects were enrolled in the study.CD_4~+ CD_(28)~(null)T lymphocytes were measured by flow cytometric analysis.Results The numbers of CD_4~+ CD_(28)~(null)T lymphocytes in patients with acute coronary syndromes were higher than those in patients with stable angina and in the control subjects(11.6 % vs 2.84% and 0.59%,P
5.Subintimal angioplasty for the treatment of chronic ischemia with arteriosclerosis occlusions in the lower extremity
Xinwu LU ; Weimin LI ; Ying HUANG ; Min LU ; Xintian HUANG ; Xiaobing LIU ; Minyi YIN ; Mier JIANG
Chinese Journal of General Surgery 2009;24(6):448-450
Objective To assess the technical feasibility, patency and outcomes of subintimal angioplasty (SIA) for treatment of the lower extremity arteriosclerosis occlusions. Methods During the period from December 2003 to August 2008, 122 lower extremities with arteriosclerosis occlusions (median length, 10.25 cm;range, 4.5 to 28 cm) were treated on an intention-to-cure basis with SIA. Twenty-three lower extremities had disabling claudication and ninety-nine had limb-threatening ischemia. Patient history, demographics, procedural details, complications, and follow-up information were collected and analyzed. Patency, limb salvage, sustained improvement in claudication was determined by Kaplan-Meier analysis. Results The technical success rate of SIA was 83%. Following successful SIA, the mean ankle-brachial index increased from 0.19±0.11 to 0.67±0.29 (P<0.01). Primary patency at 12 and 24 months was 54%±5% and 45%±4% respectively, the clinical effective rates (rates of limb salvage and improvement in claudication) at 12 and 24 months were 82%±5% and 79%±4% respectively. No serious complications occurred. Conclusion In a selected group of patients, SIA is feasible with a high technical success rate and the clinical effective rates are satisfactory, there were no severe complications. SIA is a good treatment alternative in patients suffering from chronic ischemia with arteriosclerosis occlusions in the lower extremity.
6.Revascularization of Severely Ischemic Limbs by Staged Arteriovenous Reversal.
Mier Jiang ; Ying Huang ; Min Lu ; Xintian Huang ; Xinwu Lu ; Wengxia Zhu ; Weimin Li ; Peihua Zhang
Japanese Journal of Cardiovascular Surgery 1999;28(4):215-220
Purpose: To apply staged arteriovenous reversal in the treatment of extensive and diffuse arterial occlusive disease of the limb. To avoid amputation of the limb or to limit it to necrosed segments.
Methods: Exactly 138 patients (a total of 153 severely ischemic limbs) were applied staged arteriovenous reversal (AVR) from January 1984 to December 1995. Generic-specific involvement totaled 106 men and 32 women. Their ages ranged from 24 to 71, averaging 48.7 years. The duration of symptoms ranged from 15 days to 17 years. A total of 112 patients were diagnosed as having Buerger's disease, and 25 had arteriosclerosis. In one patient, the popliteal artery was completely obstructed by acute emboli of atheromatous plaques. Three patients with Buerger's disease had not benefited from lumbar sympathectomy or partial adrenalectomy done several years ago. According to different levels of extensive and diffuse arterial occlusion, arteriovenous reversal was formed at three different sites: (1) high-deep reversal, produced between the external iliac, common femoral, or superficial femoral artery and the superficial femoral vein; (2) low-deep reversal between the distal popliteal artery and tibioperoneal venous trunk; (3) superficial reversal, established between the distal popliteal artery and distal portion of the long saphenous vein.
Results: Until June 1996, a total of 132 patients were followed up for 0.5-12 years, averaging 6.5 years. The postoperative results of all limbs except 12 in this series are excellent or good. Cardiac dysfunction does not occur, nor does the marked elevation of venous pressure of the limb.
Conclusion: We consider that if the deep venous trunks are patent, the limbs with extensive arterial occlusion are indicated for staged AVR if severe ischemia is present and all other therapeutic methods have failed. Even with necrotic limbs, this operation may lower the level of amputation. The authors suggest that staged arteriovenous reversal is a new and effective approach in the treatment of extensive arterial occlusive disease of the limb.
8.A giant solitary fibrous tumor of the pleura.
Lu-feng ZHAO ; Ying CHAI ; Li-jian HUANG
Chinese Medical Journal 2013;126(15):2999-2999
9.Identification of pelvic dose-volumetric parameters that predict acute bone marrow suppression in concurrent chemoradiotherapy for cervical cancer
Wei HUANG ; Ying LI ; Wenli LU ; Benxu TAN
Chinese Journal of Radiological Medicine and Protection 2016;36(3):207-210
Objective To identify the dose-volumetric parameters associated with acute bone marrow suppression in concurrent chemoradiotherapy for cervical cancer,and provide the reference standard for the radiotherapy planning.Methods In total,155 patients concurrently receiving chemoradiotherapy for cervical cancer were enrolled in this study.The pelvis was contoured for each patient in radiotherapy treatment planning system and divided into three subsites:lumbosacral spine,ilium,and lower pelvis.The pelvic dose volume parameters were analyzed using univariate analysis (Chi-Square and t test),and multivariate analysis (Logistic regression model).Dose volume parameters include V5,V10,V15,V20,V25,V30,V35,V40,V45,V50 and the average dose (D).Results The percentage of patients that developed acute bone marrow suppression (≥ grade 2) was 87.7% (136/155).The univariate analysis revealed that pelvic V5,V10,V15,V,0,ilium V15,lower pelvis V15 of patients with acute bone marrow suppression (≥ grade 2) were significantly higher than those of < grade 2 patients (t =-2.277,-2.142,-3.475,-2.018,-2.963,-2.741,P <0.05).Multiple regression analysis indicated that pelvic V15 was associated with acute bone marrow suppression (OR =1.728.P < 0.05).The threshold of pelvic V15 was 88% as determined by receiver operating curve (ROC).Conclusions The results show that Pelvic V15 is associated with acute bone marrow suppression in concurrent chemoradiotherapy for cervical cancer and is thus an independent risk factor.To better predict and control acute bone marrow suppression,pelvic V15 should be carefully controlled below 88% in treatment planning to reduce the incidence of acute bone marrow suppression.
10.Determination of Paraquat Adsorbability to Four field Soils of Guangxi Province by High Performance Liquid Chromatography Method
Hua LU ; Zong NING ; Daohai CHENG ; Ying QIU ; Junjie HUANG
Herald of Medicine 2015;(7):938-941
Objective To study paraquat adsorbability of different field soils in Guangxi province of China. Methods HPLC method was adopted to measure the peak area of paraquat in three different media of four types of soils. Chromatographic column was Kromasil C18 column (4. 6 mm×200 mm, 5 μm); mobile phase was acetonitrile-water (including 0. 03 mol·L-1 sodium heptanesulfonate and 0. 24 mol·L-1 phosphoric acid) at a ratio of 397 (pH adjusted to 2. 0 by triethylamine). Detection wave length was 258 nm; column temperature was 25 ℃; the injection volume was 20 μL; flow rate was 0. 8 mL·min-1 . The peak areas of paraquat before and after being adsorbed were compared to calculate the adsorption rate of paraquat in different soils. Results All tested soil samples possessed the adsorption rate of paraquat over 99. 0%. Conclusion Four common field soils in Guangxi province can be used as temporary effective absorbents for the first-aid of paraquat poisoning.