1.Unity of purpose-based medical information literacy education research
Chinese Journal of Medical Education Research 2011;10(8):1014-1016
In the process of the information literacy education, teachers, students and the society often have the conflict goals.Unity of purpose-based medical infornation literacy education research and emphasis on the decomposition of the different targets mean to extract the most important core object, so as to achieve social goals, teaching objectives and students target the greatest degree of uniformity, to achieve the maximization of the function of the information literacy education.
3.Intelligent library:Research and practice
Chinese Journal of Medical Library and Information Science 2014;(11):49-51,79
After a description of the elements in constructing an intelligent library, innovative service, and the role of intelligent librarians, the new ideas the intelligent librarians should have were pointed out with the hormonal development of intelligent library stressed .
4.Impact of celecoxib on prognosis of elderly patients with hip fracture
Yong WANG ; Yejing YANG ; Min LU
Chinese Journal of General Practitioners 2016;(2):147-150
One hundred and six patients with hip fracture admitted in hospital from 2011 to 2014 were randomly divided into two groups: 52 patients received celecoxib and parecoxib ( trial group ) and 54 patients received oxycodone hydrochloride and bucinnazine (control group).On d1 and d7 after the surgery, serum levels of C-reactive protein[(26.2 ±5.4) and (10.4 ±2.8) mg/L], tumor necrosis factor-α[(40.6 ±6.1) and (31.8 ±5.3)ng/L], interleukin-6 [(22.3 ±5.7) and (18.3 ±5.2) ng/L] and prostaglandin E2 [(181.1 ± 19.4) and (153.3 ±25.8) ng/L] in trial group were all significantly lower than those in control group [(46.1 ± 14.0) and (22.1 ±5.2)mg/L, (53.2 ±5.3) and (44.6 ±7.4) ng/L, (43.3 ±11.0) and (29.1 ±8.6)ng/L, (354.3 ±105.9) and (251.0 ±37.3)ng/L, all P<005].The length of hospital stay [(11.0 ±2.2) d], rate of lung infections (6/52) and neurological abnormality (3/52) in trial group were significantly lower than those in control group [(15.5 ±1.8) d, 15/54 and 11/54, all P <0.05].The expression of CD4 +CD45 + T cells [(34.9 ±3.7)% vs.(42.5 ±4.3)%] was reduced and CD4 +Foxp3 +T cells [(19.7 ±3.8)% vs.(6.9 ± 1.5)%] was increased at 24 h after surgery in trial group compared with control group( all P<0.05).The results indicates that calecoxib can reduce the inflammatory reaction by promoting CD4 + to Foxp3 + CD4+T cell differentiation and may improve the prognosis of elderly patients with hip fracture.
5.Effect of different angle of head on intracranial pressure and cerebral perfusion pressure in patients with severe traumatic brain injury
Lin LU ; Xinjuan DAI ; Min YANG
Chinese Journal of Practical Nursing 2016;32(35):2742-2745
Objective To investigate the effects of different angles of the head of bed on intracranial pressure (ICP) and cerebral perfusion pressure (CPP) in patients with severe traumatic brain injury. Methods A prospective self-controlled study was used. The parameters of mean arterial pressure (MABP) and cerebral blood flow on 43 patients with STBI, were measured at 0° , 10° , 20° and 30° respectively. The changes of ICP and CPP were calculated according to the formula. Results With the angles of head of bed was up from 0° to 30° , MABP gradually reduced, (102.57 ± 8.34) mmHg (1 mmHg=0.133kPa), (100.74 ± 8.12) mmHg, (97.32 ± 7.94) mmHg, (94.82 ± 8.38) mmHg, so was ICP, which were (24.50 ± 6.29) mmHg, (22.88 ± 6.18) mmHg, (19.57 ± 6.22) mmHg, (17.32 ± 6.77) mmHg, and the difference was statistically significant(F=13.38,F=14.03,P<0.01). CPP reduced slightly, (78.03 ± 5.47) mmHg, (77.86 ± 5.50) mmHg, (77.75 ± 5.61) mmHg, (75.51 ± 5.76) mmHg, but the difference was not statistically significant(F=2.09,P>0.05). For moderate increased intracranial pressure patients (ICP< 25 mmHg), when the angles of head of bed up to 20° , ICP decreased gradually to(27.46 ± 5.20)mmHg and the difference was statistically significant (F=5.97,P <0.05), however,CPP did not change significantly, which was(77.50±5.35)mmHg (F=5.03,P>0.05). Conclusions Elevating the head to 30 °can rapidly reduce the intracranial pressure and ensure enough cerebral perfusion. It is a safe and effective treatment for the similar patients in emergency rescue and nursing. At the same time, for the patients with moderate intracranial hypertension (ICP ≥25 mmHg), elevation the head of bed up to 20 ° can reduce the adverse effects of intracranial pressure adaptability shortage and the cerebral hypoperfusion, increase the safety of nursing care, and reduce the secondary brain injuries.
6.Investigation and analysis on cognition degree and behavior among medical students of professional bilingual teaching
Xianjie LU ; Min ZHOU ; Yang LI
Chinese Journal of Medical Education Research 2011;10(3):368-370
Objective To understand medical students on the awareness level, attitude , behavior and requirement of professional bilingual teaching, so as to provide reference for bilingual teaching. Methods A self- administered was conducted among medical students from different speciality. Results There was a significant difference in awareness level of professional bilingual teaching between nursing students and clinical medicine students (χ2=4.95, P<0.05). Majority students (81.3%) supported carring out bilingual teaching. Teachers and students' foreign language level, selection of bilingual textbook, teaching mode and environment of bilingual teaching are the main influencing factors on earring out professional bilingual teaching. Conclusion Professional bilingual teaching should be implemented designedly, selectively and systematically according to practice condition of different speciality and different subject.
7.Exploration and think of the tutorial system in clinical practice
Chinese Journal of Medical Education Research 2011;10(4):454-456
This paper discusses the meaning of the tutorial system on clinical practice;the qualifications,tasks and a responsibility of the tutors,expounds the role of tutors,and discusses the main problems of tutorial system of the undergraduate.
8.The establishment of audio medical English terminology corpus and its use in the terminology teaching to medical students
Fengxiang LU ; Bo YANG ; Nan MIN
Chinese Journal of Medical Education Research 2011;10(12):1511-1513
Medical students should study and enlarge their medical terminology from their medical English courses as well as bilingual courses. This ability is a key part in the cultivation of high-levelled medical talents.However,medical words are special from general English in three parts:long,great in numbers and difficult to read.These characteristics leave the medical students in a hard situation in their promotion of medical terminology.If the students are provided and guided with a convenient and efficient software based on modem education technology,they can achieve much better results.The audio medical English terminology corpus can help the medical students achieve their goal in promotion of medical termi-nology.
9.Application of subjective and objective assessment on fungal rhino sinusitis after endoscopic surgery
Lvyuan YANG ; Jiangju HUANG ; Min YANG ; Xue LU
Chongqing Medicine 2015;(16):2186-2188
Objective Study the useful effect of the subjective and objective assessmentscale in fungal‐rhino‐sinusitis (FRS) patients before and after endoscopic sinus surgery ,and thier transition rules .Methods Visual analog scale (VAS) ,sino‐nasal out‐come measures 20 (SNOT‐20) ,Lund‐Mackay CT score and Lund‐Kennedy nasal endoscopy score were used to prospective evaluate 130 cases of FRS patients at the time of before endoscopic sinussurgery ,the 3rd month and the6thmonth after survey ,and correla‐tion analysiswas took between the various scales .Results At the time ofbeforesurgery ,the 3rd month and the 6th month after the endoscopic sinus surgery ,the VAS ,SNOT‐20 ,Lund‐Mackay sinus CT scores and Lund‐Kennedy endoscopic score were significantly correlated (P< 0 .05) ,but At the time ofbeforesurgery ,VAS and Lund‐Kennedy nasal endoscopy scorehas no correlation(P>0 .05) .Except for SNOT‐20 scores at the time of 3rd month had relationship with preoperative scores(P<0 .05) ,there were no sig‐nificant relation of each scales that preoperative scores compared with 3rd month of 6th mouth(P> 0 .05) .The difference ofSNOT‐20 ,VAS ,Lund‐Kennedy nasal endoscopy scorewas statistically significant compared to each other at the time of 3rd month and the 6th month after surgery (P<0 .05) .Conclusion Subjective combined with objective scale can be a better response for patients be‐fore surgery ,which may be helpful for the choosing of operation time;combination of postoperative subjective evaluation with objec‐tive evaluation and following‐up ,may be a more effect way for patient to kmow the outcome after surgery .
10.Effects of bencycloquidium bromide on the expression of MUC5 AC induced by lipopolysaccharide in cultured human nasal epithelial cells
Min YANG ; Xue LU ; Jiangju HUANG ; Rui LONG ; Juan LI
Chinese Pharmacological Bulletin 2016;32(6):783-788
Aim Toinvestigatetheeffectofbencyclo-quidium bromide(BCQB)on mucus MUC5AC expres-sion induced by lipopolysaccharide in cultured human nasalepithelialcells(HNECs).Methods Primary culture of human nasal epithelial cells (HNECs)was randomly divided into control group (C,with no treat-ment),LPS group (LPS,with LPS 1 mg · L-1 added in),BCQB low dose group(BCQBL,with LPS 1 mg· L-1 and BCQB 10 -8 mol·L-1 added in),BCQB mid-dle dose group(BCQBM,with LPS 1 mg·L-1 and BC-QB 10 -7 mol·L-1 added in),BCQB high dose group (BCQBH,with LPS 1 mg·L-1 and BCQB 10 -6 mol· L-1 added in)and ipratropium bromide group(IB,with LPS 1 mg·L-1 and IB 10 -6 mol·L-1 added in).Af-ter incubation at 37 ℃with 5% CO2 for 24 h,the ex-pression of MUC5 AC mRNA was detected with Real-time PCR and the expression of MUC5 AC protein in HNECs was detected with Western blot,while the ex-pression of MUC5 AC protein in supernatant was detec-tedwithELISAineachgroup.Results Ascompared with control group,the expression of MUC5 AC mRNA and protein increased significantly in LPS group (each P<0. 01 ).As compared with LPS group,the expres-sion of MUC5 AC mRNA and protein decreased signifi-cantly in each group of BCQB(P<0. 01,P<0. 05), and there was no statistical difference between BCQB high dose group and control group (each P>0. 05 ). Conclusion Bencycloquidiumbromidecansuppress MUC5 AC expression induced by LPS in cultured hu-man nasal epithelial cells,indicating that BCQB may be a new drug for nasal mucous hypersecretion diseases.