Objective To explore the effect and utilization of comprehensive treatment on intrahepatic recurrence after hepatic resection for hepatocellular carcinoma.Methods One and two year recurrent rate of 60 patients with hepatocellular carcinoma who underwent hepatic resection in a two-year follow up were analyzed retrospectively,control group 30 cases,comprehensive treatment group 30 cases.Results One and two year intrahepatic recurrent rate of comprehensive treatment is 13％(4/30)and 40％(12/30)respectively.The difference was statistically singnificant(x2=4.176,4.310,all P＜0.05).Conclusion The effect of comprehensive treatment on postponing intrahepatic recurrence after hepatic resection for hepatocellular carcinoma is obvious.

BACKGROUND:Osseous deformity is one of the most common Jaw deformities in clinic, which give patients serious impact on functionality and aesthetics, so patients want to cure it strongly. Recently, Functional Magnetic System has played an increasingly important role in correcting osseous deformity because of its advantages, so it is gradual y known by people.
OBJECTIVE:This article wil give a summary of Functional Magnetic System in the progress and deficiencies, in order to have a greater development in the field of correct osseous deformity.
METHODS:We searched the PubMed database, from January 1990 to June 2013 with the key words of“magnetic, orthodontics”in English. An online search of CNKI database, Wanfang database, Chongqing VIP database from January 1990 to June 2013 was also conducted with the key words of“magnetic, orthodontics”in Chinese.
RESULTS AND CONCLUSION:Functional Magnetic System is the combination of magnetic force and the traditional function correcting device, with the aid of attraction and repulsion, we could make up for the inadequacy in the treatment of Jaw osseous deformity, including the problems of length, width and height. With the development of magnetic materials and the research of magnetic materials, Functional Magnetic System wil have a bigger development.

[Objective] To investigate the effects of the Sheng Jing Tang, one of tonyfing kidney and promoting blood circulation recipes,on female rats anovulatory due to testosterone and to study the mechanism of action of the recipe. [Methods] The rat models of anovulatory disease were established by injecting the immature female SD rat with testosterone and treated with TCM and herbs to observe estrous cycle level of sex hormone of blood and the change of pathological histology of ovary. [Results] Sheng Jing Tang could improve the level of sex hormone, contract the expanded oxarian vesicles obviously and increase the quantity of luteum. [Conclusions] Sheng Jing Tang had the effect of improving the syndromes of Polycystic Ovary, inducing ovulation and recovering the function of ovary.

In China, fall ranks the top 3 among adverse events in hospital and it is the first cause of death in the elderly aged 65 and above. Fall risk factors and characteristics, nursing assessment and nursing care interventions are reviewed in this paper to explore risk factors and further improve the nursing care interventions for falls in hospitalized elderly patients.

BACKGROUND: Imported self-locking brackets cost much. So it is necessary to develop low-cost and easy-to-operate domestic self-locking brackets.OBJECTIVE: To introduce a newly developed self-locking brackets, and investigate the frictional forces of the brackets. DESIGN, TIME AND SETTING: Biomechanical controlled analysis was performed in the Laboratory of Harbin Medical University in January 2004. MATERIALS: Self-made self-locking brackets and domestic conventional tie-wing stainless steel brackets; domestic Ni-Ti round wire, Australian stainless steel round wire, and domestic stainless steel rectangular wire. METHODS: Two kinds of brackets were combined with three kinds of arch wires. Under the drive of micromotor, pull sensor moved at 1 mm/min. An arch wire, which was ligated in the bracket, was dragged. Thus, teeth's shift was imitated.MAIN OUTCOME MEASURES: Waveshape was observed through the use of storage oscillograph and corresponding data were recorded. Frictional force was determined and compared.RESULTS: Under the same other conditions, no matter which kind of arch wires were combined with, tie-wing brackets produced greater frictional force than self-locking brackets (P < 0.001). Under the same other conditions, no matter which kind of brackets were combined with, Ni-Ti wire produced greater frictional force than Australian stainless steel round wire and domestic stainless steel rectangular wire (P < 0.001). In addition, domestic stainless steel rectangular wires produced greater frictional force than Australian stainless steel round wires (P < 0.001). CONCLUSION: Self-locking bracket produces low frictional force, so it is fit for orthodontic doctors to use the corrective force.

Objective:Discussion MKK4 protein expression in nasopharyngeal carcinoma and -1044 A/T polymorphism correlation.Methods:90 patients with nasopharyngeal carcinoma , MKK4 protein expression was determined by immunohistochemical staining,polymerase chain reaction-restriction fragment length polymorphism ( PCR-RFLP ) to detect the gene -1044A/T sites monocytes nucleotide polymorphism.Results:MKK4 protein expression in nasopharyngeal carcinoma (-) was 24.4%(22/90),(+) was 15.6%(14/90),(++) was 34.4%(31/90),(+++) was 25.6% (23/90).Low expression (-/+) patients with a total of 36 cases,-1044AA genotype accounted for 22 cases (61.11%),AT genotype accounted for 12 cases (33.33%),TT genotype accounted for two cases (5.56%),AT+TT gene type accounted for 14 cases (38.89%).The patients with high MKK4 expression of 54 cases,of which accounted for 38 cases of AA genotype (70.37%),AT genotype accounted with 15 cases (27.78%),TT genotype accounted for one case (1.85%),AT +TT genotype accounted for 16 cases (29.63%).Low expression and high expression of T gene mutation occurs no significant ( Z=0.323 , P=0.747 ) .Conclusion: MKK4 protein expression correlated with -1044 A/T gene promoter polymorphisms was no significant correlation .

The transfection efficiency of oligonucleotide and plasmid to the HL-60 cell line with lipofectaminePLUS was compared through observing the transfection rate and the expression duration of exogenous gene in the target cells. The results showed that the transfection rate of oligonucleotide to the HL-60 was about 90% - 95% and it had no obvious attenuation within 84 h. However, the plasmid transfection rate was only 5% -25% and it was decreased significantly within 60 h. It was suggested that the transfection of oligonucleotide with liposomes was better than that of plasmid.
Green Fluorescent Proteins/genetics ; HL-60 Cells ; Liposomes ; Oligonucleotides/*genetics ; Plasmids/*genetics ; Transfection

Modern medical record management is becoming more and more integrated with medical information management and computerization.With the changes in the content and mode of medical record management,the modernization of its means and the extension of its services,the managerial personnel must have such qualities as active service idea,multiple knowledge,a high sense of information,strengthened awareness of law,and abilities of communication and coordination,so as to meet the requirement of modern medical record management.

Objectives To establish an evaluation index system for general hospital's sustainable innovation ability of science and technoloby and determine the index weight. Methods Firstly, the theory of scientific and technological innovation was discussed based on the systematic analysis of the related facts from the documents. Secondly, a set of targets was drafted with methods of work breakdown structure (WBS), classification and combination from references to many other studies of science and technology evaluation, and then revised by experts who are familiar with the subject. Thirdly, the weight of each target was decided through Analytical Hierarchy Process (AHP) and questionnaires. Results A systematic and comprehensive evaluation system of the general hospital's sustainable innovation ability of science and technology, comprised 3 first-level indicators, 15 second-level indicators and 37 third-level indicators, which were proved reliable by consistency check. The weights of each indicator were also defined. Conclusions The evaluation system comprises both qualitative and quantitative indicators. The indicators not only reflect the performance of a period, but also reflect the sustainability of large general hospitals' scientific and technological innovation ability. By using the scientific consultation, analysis and statistics, the evaluation system is proved to be valid and reliable.

ays revealed that the-(167-111)bp region Was the minimal promoter of the human IRF3 gene.These results suggested that transcriptional factors such ag E2F might be involved in the transcriptional regulation of IRF3 gene.