Objective To establish the scientific, rational and standard librarian performance appraisal index system in academic library in order to adjust their working behaviors, improve their service quality and increase the overall performance of library.Methods The current librarian performance appraisal situation was investigated according to the literature and on the field inspection.The appraisal indexes and their weight were established by Delphi and step analysis.Results The 3-scale appraisal index system was established, which include 4 No.1 indexes, 10 No. 2 indexes, and 59 No.3 indexes with their weight and score displayed.Conclusion The performance appraisal index system we established can effectively arouse the enthusiasm of librarians in scientific research innovation, manage-ment or social work.

The study of tumors' proteomics is a research hotspot in China and abroad in recent years.The development of theory and technology in proteomics has provided new ideas and research field for cancer research.This paper reviewed the commonly used technical means of proteomics and its research progress on diagnosis,therapy and other aspects of pancreatic carcinoma.

With the improvement of clinical and scientific research level of pediatric retinal diseases in China,teaching in pediatric retinal diseases for medical students and residents has become increasingly important.Because infants cannot cooperate in ophthalmic examinations,this part becomes a difficult point in clinical teaching and practice.By using the RetCam,a wide-field retinal imaging system,infant's retinal images can display in real time on screen and images and videos can be recorded and reviewed after examination finished.By setting up teaching target reasonably,arranging teaching contents scientifically,and using teaching method properly,we applied multimedia-assisted instruction in teaching pediatric retinal diseases based on RetCam and enhanced teaching effect.

Objective To analyze the National Natural Science Foundation-supported papers on oncology published by domestic authors from 2013 to 2015 and existed problems. Methods The key words in the National Natural Sci-ence Foundation-supported papers on oncology published by domestic authors from 2013 to 2015 and SCI-covered journals and Chinese institutions that published the National Natural Science Foundation-supported papers on on-cology from 2013 to 2015 were analyzed by bibliometrics. Results The number of the National Natural Science Foundation-supported scientific projects and funds, the number of the National Natural Science Foundation-sup-ported papers on oncology published by domestic authors, and the academic level of SCI-covered journals that pub-lished the National Natural Science Foundation-supported papers on oncology from Chinese authors increased year by year from 2013 to 2015 . General and medical colleges and universities with affiliated hospitals or national key laboratories were the leading force in oncology. The hot spots in oncology were focused on basic research and malig-nant tumors. Conclusion The National Natural Science Foundation plays an active role in promoting the develop-ment of oncology in China. Although it-supported papers on oncology published by domestic authors increase year by year, problems are still existed, such as imbalance of institutions that publish papers on oncology and insuffi-cient influencing power of papers published by domestic authors.

Objective To study the enlightenments of precision medicine, personalized medicine, stratified medi-cine, individualized medicine, P4 medicine on the medical cause in China. Methods Core papers on precision medicine, personalized medicine, stratified medicine, individualized medicine, and P4 medicine were retrieved from SCI core collection and PubMed. The concepts of precision medicine, personalized medicine, stratified medi-cine, individualized medicine, P4 medicine were analyzed by the VOSviewer. Results The concept of personalized medicine and individualized medicine can be used alternatively and is a coverage concept. The concept of stratified medicine and precision medicine is similar and is an inclusive concept. P4 medicine is a participatory medical model for patients. Tumor, chemotherapy, cells, diabetes mellitus, pharmacogenomics, and variants are the hot spots in precision medicine. Tumor, genomics, and public policy have a tendency to be integrated. Conclusion The develop-ment of precision medicine in China needs the design at the national top level, scientific policy-making, integration of scientific research system and resources, implementation of step by step strategy, overcoming of medical difficul-ties in order to realize personalized medicine at last.

Objective To compare the conventional marrow collection with new marrow collection, in the number of cell, other tissues pollution and the background of the smear, providing the reference for future micronucleus test. Methods The mice was enthanasia and the sternums were taken.One group, using the conventional method of marrow collection, squeezing the marrow to the slide with fetal bovine serum;the other group, using 1-mL injector extracting fetal bovine serum 100μL, injecting into mice sternums and rushing out the bone marrow for circle smear.Results Two methods can meet the requirement of test, but the new marrow collection can acquire more number of cells, less the tissues pollution and more clear in the background of smear.Conclusions Comparing with the conventional marrow collection, the new method has more superiority to simplify the next cell counting.

After a description of the 6 types of reference management software ( EndNote, Mendeley, F1000Workspace, NoteExpress, King of medical literature and NoteFirst), their basic functions were comparatively analyzed.

Objective To compare the clinical effect of C3F8 and air tamponade after vitrectomy for the treatment of idiopathic macular hole (IMH).Methods A total of 54 eyes of 54 patients with IMH that had undergone 23G pars plana vitrectomy with internal limiting membrane peeling were retrospectively studied.All patients received optical coherence tomography ()CT) examination and the best corrected visual acuity (BCVA).They were divided into 2 groups.26 eyes in group A were filled with air and 28 eyes in group B were filled with C3F8.In group A,6 eyes at stage Ⅱ,20 eyes at stage Ⅲ,the minimum diameter (Dmin) of macular hole in 14 eyes was less than 400 μm,and in the other eyes was larger than 400 μm.In group B,10 eyes at stage Ⅱ,18 eyes at stage Ⅲ,the Dmin of macular hole in 15 eyes was less than 400 μm,and in the other eyes was larger than 400 μm.The differences of age,course of the disease,BCVA,fundus diameter,Dmin,height,index,diameter of outer retina diameter (Dord) between the two groups were not significant (P＞0.05).The basic data before surgery and the closure rate,BCVA,Dord 1 month after surgery between two groups were compared.Results At 1 month after surgery,the IMH closure rate was 100.0％ in group A and 92.9％ in group B,the difference between these two groups was not significant (P=0.491).The closure rate of eyes with Dmin＜400 μm were both 100.0％ in two groups,and the closure rate of eyes with Dmin＞400 μm were 100.0％ in group A and 84.6％ in group B.There was no statistically significant differences between two groups (P =0.480).The mean BCVA of two groups were 0.35±0.22 and 0.33 ±0.16 respectively.The mean Dord were (782.2 ± 478.0) μm and(792.1 ± 432.7) μm respectively.All cases got better BCVA (t=-7.310,-10.506;P＜0.01) and shorter Dord (t=6.704,7.770;P＜0.01).But there was no statistically significant differences between groups 1 month after surgery in BCVA and Dord (t =0.381,0.800;P =0.705,0.937).Conclusion Air tamponade after vitrectomy has the same efficacy as C3 F8 tamponade in the treatment of IMH.

The practicability for local hospitals to take part in bidding for research contracts is re- viewed.Four favorable conditions are pointed out.The administrative process for research contract bid- ding is divided into two aspects:one is the organization and coordination in the course of contract bid- ding;the other is the eight requirements for filling up tenders brought forth from the viewpoint of ad- ministrators.

Objective To explore the effect of family health management on community type 2 diabetes medication compliance.Methods Totally 123 patients with type 2 diabetes who live in Shanghai City Qingpu District Xujing Town An Ju Wei Hao Xiao Qu and met the WHO diagnostic criteria for type 2 diabetes were enrolled into this study.The patients' age was 50-75 years,including 60 male,63 female cases,mean age was (63.9 ± 6.9),(10.0 ± 7.4) years,course of disease,a family health file,making personalized home health management measures of community were analyzed.The effects of the 2 years of intervention on the compliance of the patients before and after the intervention as well as the blood pressure,blood glucose,blood lipid control were evaluated.Results The treatment compliance rate was (77.1％,94/122,intervention 1 cases died) significantly higher after intervention than that before intervention (62.6％,77/123) (x2=6.06,P＜0.05).After the intervention,the rate of target achievement in blood pressure (51.6％,63/122),blood glueose (44.3％,54/122),total cholesterol (72.1％,88/122),triglyceride (61.5％,75/122) low density lipoprotein (75.4％,92/122) were higher than those before intervention [blood pressure standard rate of 36.6％ (45/123),blood glucose standard rate of 28.5％ (35/123),total cholesterol standard rate of 59.3％ (73/123),triglyceride standard rate of 47.9％ (59/123),low density lipoprotein standard rate of 65.0％ (80/123)],the differences were statistically significant (x2=5.63,6.61,4.44,4.51,3.97,P＜0.05).Conclusion Community and family health management can improve the medication compliance in patients with type 2 diabetes.