1.The application of hedging in academic medical English papers
Chinese Journal of Medical Education Research 2015;14(10):1012-1015
Hedging is an important component of vague language. This paper retrieves high frequency expressions of hedgingby using medical English corpus. Pragmatic functions of hedging are analyzed, which can be summarized as politeness principle, authors' self-protection, avoidance of the absolute, pursuit of objectiveness as well as conversational implication. To medical researchers, it is necessary to cultivate the awareness of hedging and learn how to adopt it in their research papers.
2.Progress of methotrexate combined with other drugs for treatment of primary central nervous system lymphoma
Journal of Leukemia & Lymphoma 2017;26(6):375-379
Primary central nervous system lymphoma (PCNSL) is a rare type of extranodal lymphoma, and its incidence rate is increasing nowadays. Chemotherapy is the main means for treatment of PCNSL and the efficacy of high-dose methotrexate (HD-MTX) has been confirmed among those chemotherapeutics. Treatments of HD-MTX combined with other drugs have been studied extensively. Progress of HD-MTX and other drugs for PCNSL are reviewed in this article.
3.Application of permanent needle of deep venipuncture to first aid of extensive burn
Chinese Medical Equipment Journal 2003;0(10):-
Objective:To explore the clinical application of permanent needle of deep venipuncture in early management of extensive burn.Methods:88 patients with extensively burn are analyzed.Results:The success rate of venipuncture was 96%.The effect was satisfactory,while the complication was less.Conclusion:The permanent needle of deep venipuncture shows an important role in early management of extensive burn.
4.The analysis of the risk factors of the pulmonary fibrosis patients with pulmonary fungal infection
Chinese Journal of Primary Medicine and Pharmacy 2011;18(18):2485-2486
ObjectiveTo investigate the risk factors,prevention measures and treatment methods of the pulmonary fibrosis patients with nosocomial pulmonary fungal infection. Methods50 pulmonary fibrosis patients with nosocomial pulmonary fungal infection were chosen as the observation group. In the same time,50 pulmonary fibrosis patients without nosocomial pulmonary fungal infection were chosen as the control group. The following factors were compared: hospital stay, corticosteroid use, antibiotic use, invasive procedures, a merger of the underlying disease.ResultsThere were 46% (23/50) patients had long-term use of antibiotics in the observation group, much more than the control group(26% ,13/50) ,the difference was statistically significant( P <0.05) ;More than half of patients in both groups using glucocorticoids, the ratio in the observation group was 84% (42/50), which was significantly higher than the control group( P < 0.05) ; In the observation group, the rates of patients with long time hospitalization ( ≥30 days), received invasive procedures, and associated with underlying diseases were much higher than the control group( all P < 0.05). ConclusionMultiple risk factors could lead to the occurrence of pulmonary fibrosis patients with nosocomial pulmonary fungal infection,and the positive and effective preventions and standard treatment should be taken.
6.Study of correlation between blast lung injury and acute posttraumatic stress disorder
Chinese Journal of Behavioral Medicine and Brain Science 2012;21(5):399-402
ObjectiveTo study the correlation between blast lung injury (BLI) and acute posttraumatic stress disorder(PTSD) through the establishment of the model about blasting injury of rats.Methods84 SD male rats were randomly divided into four groups:the normal control group( A),the model groups ( B,C) and the sham model group(D).21 rats in each group.The chest of the model group and sham model group rats,respectively,were exposed to 8# instantaneous electric detonator at different distances.Then,emotion and behavior of rats was observed through open field test and elevated plus maze test,at day 1,14,28 after blasting.Group A was not given the explosion of stress treatment.After testing,each group was randomly picked up seven rats for succumbing to draw blood which was used to detecting the level of plasma corticosterone by radioimmunoassay,respectively.Results( 1 ) On day 1,it was a significant difference that the latency time ( LT),crossing frequency (CF),rearing frequency(RF) and modification frequency(MF) which were both group B( (25.34 ± 4.50)s,( 19.73 ± 11.10 ),(0.52±0.11),(0.53±0.21) respectively)and group C((22.13 ±6.54)s,(28.67 ±7.22),(1.07 ±0.26),( 0.89 ± 0.15 ) respectively ) were compared with group A,including LT,CF and RF of group D ( ( 23.71 ± 3.9 ) s,(25.13 ± 12.35 ),( 1.26 ± 0.74 ) respectively ) (P < 0.05 ).Then,on day 28,although there was a significant difference which both the LT,CF and RF of group B,and the CF and RF of group C were compared with group A(P < 0.05 ),no significant discrepancy was observed between group B and C (P > 0.05 ).( 2 ) In the elevated plus maze test,the result was similar to the open field test.(3)On day 1 after blasting injury,it was significant distinction that the level of serum corticosterone of group B,C and D (( 153.15 ± 44.50) ng/ml,( 132.72 ±78.77)ng/ml,(96.16 ±8.96)ng/ml respectively)were higher than group A(P<0.05).Finally,the level of serum corticosterone of group B,C and D were lower than group A on day 28 (P < 0.05 ).ConclusionBLI model successfully induces acute stress disorder(ASD) of rots which behaved like anxiety,fear,hyperarousal and avoidance,and promots furtherly the development of ASD to PTSD,and establishes the modle of acute PTSD.
7.Associations of metabolism of lipid,calcium and phosphate in endometriosis
Chinese Journal of Obstetrics and Gynecology 2008;43(3):185-188
Objective To investigate the metabolism of lipid,calcium and phosphorus in women with endometriosis.Methods Clinical data of 223 patients with endometriosis and 200 patients without endometriosis were retrospectively analyzed.Electrochemiluminoimmunoassay was used to detect the levels of serum luteinizing hormone(LH),follicle-stimulating hormone(FSH),testosterone(T),estradiol(E2)and progesterone(P),and photoelectric colorimetry was used to determine the concentrations of serum triglyceride ( TG), total cholesterol ( TC ), low density lipoprotein ( LDL), high density lipoprotein (HDL), calcium and phosphorus in the patients with and without endometriosis. Results The levels of serum P were 2. 0 nmol/L and 1.8 nmol/L in endometriosis patients with age≤35 years old (case group A)and >35 years old (case group B), and 1.6 nmol/L and 1.2 nmol/L in patients without endometriosis at age≤35 years old (control group A) and > 35 years old (control group B), respectively. A significant difference was found between case group A and control group A, and between case group B and control group B. The levels of serum LH was significantly higher in case group B (7. 2 U/L) than that in control group B (6. 1 U/L), however, there was no significant difference between case group A (7. 0 U/L) and control group A (6. 5 U/L). Also no significant difference in serum FSH, T and E2 levels was found between case group A (respectively, 6.2 U/L,1.1 nmol/L and 269 pmol/L) and control group A (respectively, 6.3 U/L, 1.1nmol/L and 264 pmol/L), also between case group B (respectively, 6.6 U/L, 1.0 nmol/L and 345pmol/L) and control group B (6. 6 IU/L, 0. 9 nmol/L and 279 pmol/L). The concentrations of serum TG in case group A and B (0. 71 mmol/L and 0. 72 mmol/L) were significantly lower than in control group A and B (0. 92 mmol/L and 1.08 mmol/L), respectively. The concentrations of serum LDL in case group A and B [ (2. 2 ± 0. 5) mmol/L and (2.4 ± 0. 6) mmol/L]were also significantly lower than in control group A and B[ (2. 4 ± 0. 7) mmol/L and (2. 62 ±0. 63) mmol/L], respectively. However, the concentrations of serum HDL in case group A and B [ (1.62 ± 0. 31) mmol/L and(1.53 ± 0. 32) mmol/L] were significantly higher than in control group A and B [ ( 1.48 ± 0. 21 ) mmol/L and ( 1.37 ± 0.22) mmol/L], respectively.In addition, the concentrations of serum TC were not significantly different between case group A and control group A [ (4. 2 ± 0. 7) mmol/L and (4. 29 ± 0. 71 ) mmol/L], and between case group B and control group B [ (4. 4±0. 8) mmol/L and (4. 5±0. 7) mmol/L]. The levels of serum phosphorus in case group A and B [ (1.01 ± 0. 22) mmol/L and (0. 89 ± 0. 18 ) mmol/L] were significantly lower than in control group A and B [ ( 1.23 ± 0. 24) mmol/L and ( 1.10 ±0. 13 ) mmol/L ] , respectively. But the levels of serum calcium had no significant difference between case group A and control group A [ (2. 39 ± 0. 23 ) mmol/and (2.41 ± 0. 12) mmol/L], and between case group B and control group B [(2.40 ± 0.28) mmol/L and (2. 42 ±0. 20) mmol/L]. Conclusion The abnormal metabolism of lipid and phosphorus, and the higher levels of serum P may playing a role in the pathogenesis of endometriosis.
8.A review of medical image compression techniques
International Journal of Biomedical Engineering 2008;31(2):77-81
As the increasing of digital imagilag modalities,a close-at-hand challenge to deal with is the storage and transmission requirement of enormous data of medical images.Compression is one of the indispensable techniques to solve this problem.A comprehensive review and discussions are made in this paper over the medial image compression techniques applied in medical image domain,including the latest achievements in this field.Different compression algorithm including ROI-based coding,lossless compression,DWT,neural net are introduced and some quality evaluation methods are introduced.Foreground of the field is given from our point of view.
9.The cost-effect iveness analysis of patients with urinary tract infection treated with moxifloxacin and gatifloxacin
Chinese Journal of Postgraduates of Medicine 2009;32(18):17-19
Objective To estimate the curative effect and cost-effectiveness of moxifloxacin and gatifloxacin for treatment of urinary traet infection. Methods Eighty patients with urinary tract infection were randomly divided into treatment group (40 cases) and control group (40 cases). The patients in treatment group were given 400 mg moxifloxacin once a day for 7 d, while in control group were given 400 mg gatifloxacin once a day for 7d. Results The total clinical effective rate of treatment group and control group were 95.0%(38/40) and 92.5%(37/40) respectively, and the bacterial eliminating rate were 77.50% (31/40) and 76.92% (30/39), and the rate of adverse reaction were 5.0% ( 2/40 ) and 7.5% (3/40) respectively. There was no significant difference between two groups (P>0.05). The cost-effectiveness ratio of moxifloxacin was 2296 and 779 for gatifloxacin (P<0.01). Conclusion The therapeutic scheme of gatifloxacin seems to be the best one for treating urinary tract infection.
10.Treatment of Tossy Ⅱ & Ⅲ dislocation of acromioclavicular joint using rivets with thread
Chinese Journal of Orthopaedics 2011;31(7):744-748
Objective To study the treatment effect of rivet with thread,instead of clavicular hook plate,for Tossy Ⅱ & Ⅲ dislocation of acromioclavicular joint.Methods From January 2008 to February 2009,totally 31 patients with Tossy Ⅱ or Ⅲ dislocation of acromioclavicular joint were treated using rivets with thread,including 19 males and 12 females at the age of 33-49 years(mean,41 years).Among these patients,19 suffered fresh acromioclavicular joint dislocation,9 suffered old acromioclavicular joint dislocation,and 3 did a failed fixation by clavicular hook plate.None of them was combined fracture.Mitek 3.0 mm rivet with thread was embedded to coracoid,with nonabsorbable thread connected with the rivet passing through the clavicle for fixation,and meanwhile ligament coracoclaviculare was restored or acromiocoracoid ligament displaced.Among them,12 patients assisted Kieschner wire fixation.The treatment effect was evaluated using Japanese Orthopaedic Association(JOA)scoring system and acromioclavicular joint dislocation scoring system.Results All patients were followed up 11-23 months(mean,17 months).In the patients without Kieschner wire fixation,JOA shoulder score was 65-95,excellent for 8 cases,good for 9,fine for 1,poor for 1,excellent and good rate was 89.47%(17/19);In the patients with Kieschner wire assisted fixation,JOA shoulder score was 74-97,excellent for 5,good for 4,fine for 3; the excellent and good rate was 75.00%(9/12).With acromioclavicular joint dislocation scoring system,the overall excellent and good rate was 94.74%(18/19),and 91.67%(11/12)respectively.No complication that affected joint function was found.Conclusion Rivets with thread can be used for treating Tossy Ⅱ & Ⅲ dislocation of acromioclavicular joint.This surgical technique is characterized by small operation wound,fewer complications,no secondary operation,and satisfactory treatment effect.