Objective To investigate the application value of breathing machine noninvasive positive pressure ventilation in acute myocardial infarction patients with left ventricular failure.Methods 70 acute myocardial infarction patients with left ventricular failure were randomly divided into observation group and control group,the control group received conventional treatment,on the basis of the control group,patients in the observation group were treated with noninvasive positive pressure ventilation.The treatment indicators and the proportion of converted to endotracheal intubation,mortality and length of hospital stay were compared between the two groups.Results Compared with the control group,the PaCO2,RR,HR and SBP of observation group reduced more significantly,PaO2 and SaO2 increased more significantly(t =4.2588,5.144,7.127,4.2814,6.4719,6.2629,all P ＜ 0.05).Compared with the control group,the SV and EF of observation group increased more significantly,CVP decreased more significantly (t =12.0527,14.0937,14.6425,all P ＜0.05).The patients converted to endotracheal intubation and mortality ratio were significantly lower than the control group,the average length of stay was significantly shorter than the control group(x2 =4.6289,4.2000,t =6.3892,all P ＜ 0.05).Conclusion In the treatment of acute myocardial infarction patients with left ventricular failure,noninvasive positive pressure ventilation can significantly improve cardiac function,lung ventilation and ventilatory function,increase the therapeutic effect.

Fetal heart rate (FHR) baseline estimation is of significance for the computerized analysis of fetal heart rate and the assessment of fetal state. In our work, a fetal heart rate baseline correction algorithm was presented to make the existing baseline more accurate and fit to the tracings. Firstly, the deviation of the existing FHR baseline was found and corrected. And then a new baseline was obtained finally after treatment with some smoothing methods. To assess the performance of FHR baseline correction algorithm, a new FHR baseline estimation algorithm that combined baseline estimation algorithm and the baseline correction algorithm was compared with two existing FHR baseline estimation algorithms. The results showed that the new FHR baseline estimation algorithm did well in both accuracy and efficiency. And the results also proved the effectiveness of the FHR baseline correction algorithm.
Algorithms ; Female ; Heart Rate, Fetal ; Humans ; Pregnancy ; Reference Values

A computerized fetal ECG(FECG)system is presented,w hi ch is composed of two components.One is the data collection device with a PIC m icrocomputer as the main hardware,which has low power consumption and gets power supply through serial port.The other is a software platform based on PC,which i s built through LabView6.1,a graphic programming language.Plenty of modules prov ided by LabView6.1utilized,it is efficient to develop the software platform.In particular,the implementation of the matched filtering algorithms is introduced ,which is the core of the software platform.A new method of updating templates o f matched filter is described.

In recent years, 40Hz auditory steady state response (ASSR) has been paid more attention when the depth of anaesthesia monitored because its same source with the middle latency auditory evoked potential (MLAEP), strong anti-jamming ability and close relationship with consciousness level. This article brings forward some effective and steady methods for extracting ASSR according to its characteristics. The results of these methods are analyzed and compared based on the actual records from clinical practice. And thus an extraction method fit for monitoring the depth of anaesthesia is determined.

Objective: Cervical smear screening for abnormal cells plays an important role in reducing the mortality of cervical cancer. However, all smears must be approved by the naked eyes using microscopes, and there has been a higher false-positive rate and false-negative rate. Methods: To solve this problem, the thin-layer cytology assistant screening system was developed. On the hardware side, the traditional computer-aided analysis system was improved; and on the software side, gray level transformation, edge detection, image mosaic, and some other image processing methods were introduced; and by the use of neural network, the system could realize the function of acquisition, mosaic, process, measure and recognition of the liquid-based cytology image. Results: This system was brought into the test of 150 thin-layer cytology technology(TCT) cervical cell samples, and the agreement between the results of computer-aided analysis and the manual analysis by pathology experts exceeded 90%. Conclusion: Both the traditional Pap smear and TCT preparation smear can be diagnosed by this system. As a result, the false-positive rate and false-negative rate of the cervical smear screening will be significantly reduced, meanwhile, work efficiency of pathologist can be greatly improved.

LEEP electro-scalpel is a type of cervical disease device. It belongs to the high frequency electro-knife in medical apparatus category. There is no domestic LEEP electro-scalpel at present. It is significant and important for the study group to resolve the safety and EMC problem and develop domestic LEEP electro-scalpel which is safe, stable and competitive in price while has the same surgery effect as the imported one.

ObjectiveTo investigate the effects of budesonide inhaled on the levels of interleukin-8 (IL-8), C-reactive protein (CRP) and procalcitonin (PCT) in bronchoalveolar lavage fluid (BALF) of patients with AECOPD treated by using inhalation of budesonide in different doses or by using injection of dexamethasone. MethodsNinety AECOPD patients with mechanical ventilation in ICU ward were enrolled from Jan. 2008 through Sep. 2010. All patients were selected in this study as per the criteria of AECOPD set by the Chinese Medical Association. Ninety AECOPD patients treated with routine therapy were randomly (random number) divided into 3 groups. The patients of group A were given budesonide 2 mg inhaled 1 time/d. The patients of group B was given budesonide 4 mg inhaled 1 time/d. The patients of group C had dexamethasone 2. 5 mg injected 1 time/12h. The changes of IL-8, PCT and CRP in both BALF and serum were respectively detected in three groups at the beginning of treatment, and 3 days and 7days after treatment. The detected data of variables were analyzed by SPSS 13.0 package. ResultsThe level of IL-8 in BALF declined in 3days and 7days after treatment, and the magnitude of decrease in the following order:Group B ( budesonide 4mg/d) ＞ Group A ( budesonide 2 mg/d) ＞ Group C ( intravenous dexamethasone)with significant differences among them ( P ＜ 0. 05 ). The decrease in IL-8 in serum showed the similar trend, but there were no statistical differences among them. The CRP and PCT in both BALF and serum had no significant changes. There was a correlation between the concentration of IL-8 in BALF and the duration of mechanical ventilation.Conclusions The treatment with the inhalation of budesonide could more significantly reduced the IL-8 level in BALF compared with intravenous dexamethasone, whereas the CRP and PCT were not changed. The dynamic changes of IL-8 in BALF might be used as an indicator of prognosis in AECOPD patients with mechanical ventilation.

Transcuataneous electrical nerve stimulation (TENS) analgesia as a non-drug method has received people's more and more attention recently. Considering problems of existing products, such as unstable performance and unsatisfied effectiveness, we developed a new analgesia therapy system for delivery based on bio-feedback TENS in our laboratory. We proposed a new idea for stimulation signal design, that is, we modulated a middle frequency signal by a traditional low frequency TENS wave in the new system. We designed different prescription waves for pain relief during a uterine contraction or massage between contractions. In the end, a bio-feedback TENS method was proposed, in which the waveforms of stimulation signals were selected and their parameters were modified automatically based on feedback from uterine pressure, etc. It was proved through quality tests and clinical trials that the system had good performance and satisfied analgesia effectiveness.
Analgesia ; methods ; Biofeedback, Psychology ; methods ; Female ; Humans ; Pain Management ; Transcutaneous Electric Nerve Stimulation ; methods ; Uterine Contraction

Objective To study the effect of endoscopic devascularization of perforating vein(EDPV)on the treatment of varicose veins with perforating vein insufficiency in lower limbs. Methods Clinical data of 40 patients (53 limbs) with lower limbs varicose veins underwent EDPV were retrospectiely analyzed. Results All patients lower limb ulcers healed in 5～25 days after operation.All patients were followed up for 14 (5～19)months,and no reccurence was found yet. The pigmentation of leg greatly decreased. Conclusions The EDPV is an effective procedure with fewer complications in treating the patients with varicose veins with perforating vein insufficiency in the lower limbs,EDPV has great value of clinical application.

The ambulatory EEG recorder designed in this paper can continuously record 24-hour EEG signals on 18 channels. C8051F020, a kind of mixed-signal ISP FLASH MCU, controls all the functions such as sampling, storage and many others. The 12-bit ADC in C8051F020 samples the EEG signal amplified by the preamplifier. At the same time, the EEG signal of every channel can be selected through the keyboard to be displayed on LCD so that the working status can be detected. After the system is ready, the signals sampled during 24 hours are stored into the CompactFlash card as FAT16 files.