Recently, various modalities for noninvasive reduction of adipose tissue, including cryolipolysis, radiofrequency, low-level laser therapy, and high-intensity focused ultrasound, have become available. Among these modalities, cryolipolysisis can selectively target certain tissues rich in lipids. Many preclinical and clinical studies have established the safety and efficacy of cryolipolysis for noninvasive body contouring. However, it can lead to serious adverse effects when performed by untrained clinicians. Thus, to promote the proper and safe use of cyolipolysis, we have summarized the history, basic principles, and adverse effects of cyolipolysis.
Adipose Tissue ; Low-Level Light Therapy ; Ultrasonography

Low-level laser or light therapy (LLLT) was used to accelerate wound healing without the use of thermal effects in the early days. Although the exact mechanism of LLLT is still unclear, it has been recognized as a photobiomodulation process. Today, LLLT is being credited as a non-invasive treatment modality, and in particular, being widely applied in the field of dermatology. In this review, we summarize the basic principles and clinical applications of LLLT to provide an up-to-date guidance on its practical and safe uses. Further studies are needed to elucidate the mechanism of action of LLLT in various indications, and to determine the wavelength and dose for optimal clinical use.
Dermatology* ; Low-Level Light Therapy ; Phototherapy ; Wound Healing

In the present study, we evaluated the effect of CGM on osteogenic differentiation of cultured osteoblasts, and determined whether combination treatment with LLLT had synergistic effects on osteogenic differentiation. The results indicated that CGM promoted proliferation, differentiation, and mineralization of osteoblasts at the threshold concentration of 10 µg/ml; whereas, CGM showed cytotoxic properties at concentrations above 100 µg/ml. ALP activity and mineralization were increased at concentrations above 10 µg/ml. CGM in concentrations up to 10 µg/ml also increased the expression of osteoblast-activated factors including type I collagen, BMP-2, RUNX2, and Osterix. The CGM (50 µg/ml) and LLLT (80 mW for 15 sec) combination treatment group showed the highest proliferation levels, ALP activity, and mineralization ratios. The combination treatment also increased the levels of phosphorylated forms of p38, ATF2, PKD, ERK, and JNK. In addition, the osteoblast differentiation factors including type I collagen, BMP-2, RUNX2, and Osterix protein levels were clearly increased in the combination treatment group. These results suggested that the combination treatment of CGM and LLLT has synergistic effects on the differentiation and mineralization of osteoblastic cells.
Collagen Type I ; Gingiva* ; Low-Level Light Therapy* ; Miners ; Osteoblasts*

There are several methods for the treatment of herpetic neuralgia, but there is no method that results in complete remission. Laser has lately come into use to reduce several acute or chronic pains. In order to determine the degree of pain relief by lasers, 26 patients of herpetic neuralgia were irradiated with both He-Ne and Ga-Al-As lasers twice to theree times per week and the results were analysed using visual analogue scale. The results were as follows. 1) The improving rate after 15 irradiations of laser was 63% 2)The highest improving rate(24%) was shown after one irradiation of laser(p<0.05). 3) Only one patient above age 60(3.8%) developed postherpetic neuralgia. 4) There was no significant differenc of effects of LLLT between above and below age 60. These results suggest that LLLT is non-invasive and simple method which was effective not only in controlling the herpetic neuralgia but in perventing the postherpetic neuralgia.
Chronic Pain ; Humans ; Low-Level Light Therapy* ; Neuralgia* ; Neuralgia, Postherpetic

There are several methods for the treatment of herpetic neuralgia, but there is no method that results in complete remission. Laser has lately come into use to reduce several acute or chronic pains. In order to determine the degree of pain relief by lasers, 26 patients of herpetic neuralgia were irradiated with both He-Ne and Ga-Al-As lasers twice to theree times per week and the results were analysed using visual analogue scale. The results were as follows. 1) The improving rate after 15 irradiations of laser was 63% 2)The highest improving rate(24%) was shown after one irradiation of laser(p<0.05). 3) Only one patient above age 60(3.8%) developed postherpetic neuralgia. 4) There was no significant differenc of effects of LLLT between above and below age 60. These results suggest that LLLT is non-invasive and simple method which was effective not only in controlling the herpetic neuralgia but in perventing the postherpetic neuralgia.
Chronic Pain ; Humans ; Low-Level Light Therapy* ; Neuralgia* ; Neuralgia, Postherpetic

Low level laser therapy (LLLT) is a therapeutic method which regulates the biological behavior of cells with light. The effects of LLLT consist of promotion of tissue repair, inhibition of inflammation, and relief of pain by promoting or inhibiting the cell proliferation, increasing or decreasing the release of some bioactive substances. Therefore, LLLT is also known as photomodulation. At present, there are many relevant experimental studies of LLLT abroad, and they are also used clinically. This article reviews the effect of LLLT on wound healing.
Humans ; Low-Level Light Therapy ; methods ; Wound Healing

No abstract available.
Coronary Artery Bypass ; Coronary Vessels ; Low-Level Light Therapy

At present, current stimulation, ultra-sound, and light therapy have become effective methods to promote wound healing. Among them, infrared light is the most widely used method and is one of the important methods to promote wound healing. The therapeutic effect of infrared light on wounds is related to the effect of photobiomodulation on cells and molecules on the skin surface, but the mechanism by which photobiomodulation of infrared light promotes wound healing has not been fully elucidated. Therefore, it is necessary to study the action characteristics and the mechanism of photo-biomodulation of infrared light in promoting wound healing. This article reviews the effect of different types of infrared light on wound healing and the mechanism of infrared light in promoting wound healing.
Infrared Rays ; Low-Level Light Therapy/methods* ; Wound Healing/physiology*

OBJECTIVETo evaluate effectiveness of low-level laser therapy (LLLT) on temporomandibular joint (TMJ) pain.

METHODSThe patients with TMJ pain were randomly assigned laser group (n=21) or control group(n=21), once a day for 6 consecutive days of treatment. TMJ pain and function were measured at baseline, just after treatment course, 1 month and 2 months after the treatment.

RESULTSThe changes of visual analogue scale (VAS) were appearing over time in both groups but presented statistically significant differences between groups (P<0.001). VAS of laser group decreased faster than that of control group. The same tendency occurred for painless maximum vertical opening (MVO), left lateral excursion (LLE) and right lateral excursion (RLE), which increased faster in laser group. There were no statistically significant differences between groups and evaluation times for protrusion excursion (PE), but an interaction between group and evaluation times existed and should be explored further.

CONCLUSIONLLLT is an appropriate treatment for TMJ pain.

The development of TCM acupuncture represents a internationalized and modern trend. A recent study with the title of "Acupuncture for chronic knee pain: a randomized clinical trial" published in Journal of the American Medical Association on October 1st, 2014, which raised doubts on acupuncture efficacy as well as traditional manipulation and acupoint theory, makes some negative impact and challenges on the development of acupuncture. From the view of future development of acupuncture, the potential influence of this research on acupuncture development is proposed, and by combining acupuncture theory, some discussions and doubts on the research design and outcome explanations are made. Additionally, enlightenments of this research on further clinical research are summarized.
Acupuncture Therapy ; Chronic Pain ; therapy ; Female ; Humans ; Low-Level Light Therapy ; Male