1.Managing breast cancer diagnosed in first trimester pregnancy: a case report.
Ramesh WIJAYA ; Wei Sean YONG ; Allen W Y YEO ; Diana T H SEE
Annals of the Academy of Medicine, Singapore 2007;36(12):1024-1027
INTRODUCTIONBreast cancer is the most common malignancy in pregnant women, occurring at a rate of about 1 in 3000 pregnancies. Unfortunately, this will sometimes occur during the first trimester of pregnancy and this situation warrants discussion of management options with regard to the mother and child, especially with the current trend of deferring child bearing to a later age.
CLINICAL PICTUREWe present a 34-year-old primigravida who had a breast lump prior to confirmation of her pregnancy and received her diagnosis of invasive breast cancer at 7 weeks' amenorrhoea. The oncologic management options of this pregnant patient with breast cancer are discussed.
TREATMENTThe patient eventually opted to undergo wide excision of the breast cancer with sentinel lymph node biopsy and possible axillary clearance together with termination of her pregnancy.
RESULTSThe patient successfully underwent surgery for her breast cancer and was subsequently treated with adjuvant therapy as per normal protocol for a non-pregnant patient.
CONCLUSIONThe management of breast cancer and pregnancy occurring concurrently is a complex problem fraught with many dilemmas for both the medical team, the patient and her family. The option chosen must involve a multidisciplinary team and have full informed consent of the patient.
Abortion, Induced ; Adult ; Breast Neoplasms ; diagnosis ; drug therapy ; surgery ; Female ; Humans ; Pregnancy ; Pregnancy Trimester, First ; Sentinel Lymph Node Biopsy
2.Ministry of Health Clinical Practice Guidelines: Hypertension.
Jam Chin TAY ; Ashish Anil SULE ; E K CHEW ; Jeannie S TEY ; Titus LAU ; Simon LEE ; Sze Haur LEE ; Choon Kit LEONG ; Soo Teik LIM ; Lip Ping LOW ; Vernon Min Sen OH ; K Y PHOON ; Kian Wee Kenneth TAN ; Akira WU ; Loo See YEO
Singapore medical journal 2018;59(1):17-27
The Ministry of Health (MOH) has updated the clinical practice guidelines on hypertension to provide doctors and patients in Singapore with evidence-based treatment for hypertension. This article reproduces the introduction and executive summary (with recommendations from the guidelines) from the MOH clinical practice guidelines on hypertension, for the information of SMJ readers. Chapters and page numbers mentioned in the reproduced extract refer to the full text of the guidelines, which are available from the Ministry of Health website: http://www.moh.gov.sg/content/moh_web/healthprofessionalsportal/doctors/guidelines/cpg_medical.html. The recommendations should be used with reference to the full text of the guidelines. Following this article are multiple choice questions based on the full text of the guidelines.
Antihypertensive Agents
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therapeutic use
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Blood Pressure
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Evidence-Based Medicine
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Health Promotion
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Humans
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Hypertension
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diagnosis
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therapy
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Life Style
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Risk Factors
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Singapore