Purpose Hypertensive patients often experience both cardiac and vascular function changes. Traditional ultrasonography has limitations. This paper applies carotid artery wave intensity (WI) technology combined with omni-directional M-mode echocardiography (OME) to evaluate integral cardiovascular function of patients with hypertension to assess the application of WI and OME in evaluating cardiovascular function. Materials and Methods Thirty healthy subjects were selected as control group; 61 patients with primary hypertension were selected as hypertension group, among which 30 cases were in non-cardiac hypertrophy group (group A), and 31 cases in cardiac hypertrophy group (group B). WI technique was adopted to measure parameters such as transient acceleration wave intensity (W1), transient deceleration wave intensity (W2), and instantaneous wave intensity negative area (NA) of carotid artery. OME was used to measure parameters such as velocity, accelerated velocity, and relative force of systolic endocardium of the six segments of left ventricular short-axis papillary muscles level. Results W1 and NA of hypertension group A and B were higher than those of the control group [W1: (9.918±1.853) mmHg·m/s3 vs. (11.710±3.188) mmHg·m/s3 vs. (8.223±1.450) mmHg·m/s3; NA: (31.684±9.109) mmHg·m/s3 vs. (36.889±10.221) mmHg·m/s3 vs. (23.673±6.629) mmHg·m/s3, P<0.01]. W1 in group B was greater than that in group A, the difference of which was statistically significant (P<0.05). The difference of NA between groups A and B was not statistically significant (P>0.05). The difference of W2 among the three groups was not statistically significant (P>0.05). The difference of peak velocity and accelerated velocity of systolic endocardium among the three groups was not statistically significant (P>0.05). The systolic relative forces of the six segments in group A and B were slightly larger than those in control group, except for the anterior wall of group B (80.33±13.00) cm2/s2, and the difference among other walls was not statistically significant (P>0.05); the sum of systolic relative force of the six segments in group A and B was greater than that in control group [(428.75±39.36) cm2/s2 ratio (451.70±33.83) cm2/s2] vs. (400.51±51.57) cm2/s2, P<0.05]; the sum of systolic relative force of the six segments in group B was greater than that in group A (P<0.05), the difference of which was statistically significant; W1 and the sum of systolic relative force of the six segments of left ventricular short-axis papillary muscle in three groups were correlated (r=0.239, P<0.05). Conclusion WI combined with OME can comprehensively evaluate cardiovascular function of hypertensive patients.