Objective: To observe the effect of Zhen′gan Xifeng decoction combined with mirror therapy on the recovery of upper limb function of stroke patients with syndrome of Yin deficiency and wind stirring. Methods: From January 2015 to October 2017, 90 stroke patients with syndrome of Yin deficiency and wind stirring complicated with hemiplegia of upper limbs in Wenzhou Hospital of Traditional Chinese Medicine were randomly divided into the combined treatment group, the mirror treatment group and the control group according to the digital table, with 30 cases in each group.All patients were treated with conventional western medicine, combined with limb function rehabilitation training; on this basis, the combined treatment group was given mirror therapy in conjunction with Zhen′gan Xifeng decoction, the mirror group was given mirror treatment, the control group only received routine treatment.The three groups were treated for 8 weeks.The recovery of upper limb function score(FMA), arm action test score(ARAT), functional independent measurement(FIM) were used to evaluate the curative effect, and the TCM syndrome scores of the patients before and after treatment were compared in the three groups. Results: After treatment, the FMA scores, ARAT scores and FIM scores of the three groups were higher than those before treatment(all P<0.01). The upper limb FMA score[(33.80±7.17)points], ARAT score[(13.57±4.62)points], FIM score[(69.54±19.23)points] in the combined treatment group were significantly higher than those in the mirror group[(25.90±6.47)points, (11.57±3.84)points and (59.89±22.56)points, P=0.001, 0.036, 0.001] and the control group[(21.90±4.87)points, (10.32±3.21)points, (49.80±23.51)points, P=0.001, 0.025, 0.000]. The Ashworth upper limb spasticity score in the combined treatment group[(1.23±0.34) points] was significantly lower than that in the mirror group[(1.91±0.46)points, P=0.048]and the control group[(1.72±0.51)points, P=0.043], compared with before treatment, the scores in the mirror group and the control group had no statistically statistical differences(t=0.58, P=0.290, t=1.21, P=0.079). The effectiveness of the combined treatment group was 24 cases after treatment of TCM syndrome, and 18 cases were effective in the mirror group, and 6 cases were effective in the control group. Conclusion The combination of Zhen′gan Xifeng decoction and mirror therapy can better improve the upper extremity motor function of the stroke patients with syndrome of Yin deficiency and wind stirring, promote the recovery of the motor function of the affected side and improve the daily living ability of the patients.The improvement of upper limb spasm is more effective, it is worthy of clinical promotion.